Major facilitator superfamily (MFS) profile
Phosphoadenosine phosphosulphate reductase
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
TonB-dependent receptor-like beta-barrel
Secretion system C-terminal sorting domain-containing protein
DNA replication/recombination mediator RecO N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Penicillin-binding protein transpeptidase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Polysaccharide biosynthesis protein CapD-like
Pyrroline-5-carboxylate reductase catalytic N-terminal
Outer membrane protein beta-barrel domain-containing protein
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Peptidase S9 prolyl oligopeptidase catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pyruvate phosphate dikinase AMP/ATP-binding
Histidine-specific methyltransferase SAM-dependent
NIF system FeS cluster assembly NifU N-terminal
Putative exodeoxyribonuclease 8 PDDEXK-like
Tryptophan synthase beta chain-like PALP
Glycosyl transferase family 3 N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Resolvase/invertase-type recombinase catalytic
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Sodium/calcium exchanger membrane region
Putative auto-transporter adhesin head GIN
Haem-binding uptake Tiki superfamily ChaN
Plays an important role in substrate specificity
Important for beta-aspartyl-AMP intermediate formation
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Terminase large subunit gp17-like C-terminal
Trigger factor ribosome-binding bacterial
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Mandelate racemase/muconate lactonizing enzyme C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
RND efflux pump membrane fusion protein barrel-sandwich
Cationic amino acid transporter C-terminal
Long-chain fatty acid transporter permease
S-adenosylmethionine-dependent methyltransferase
Beta-lactamase-related domain-containing protein
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
O-(3'-phospho-DNA)-tyrosine intermediate
Phosphatidic acid phosphatase type 2/haloperoxidase
Alginate export domain-containing protein
Gylcosyl hydrolase 115 C-terminal domain-containing protein
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Lysidine-tRNA(Ile) synthetase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
SusC/RagA family TonB-linked outer membrane protein
Peptidase M1 membrane alanine aminopeptidase
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Glycosyl hydrolase family 30 beta sandwich
Polysaccharide biosynthesis protein C-terminal
RagB/SusD family nutrient uptake outer membrane protein
BAAT/Acyl-CoA thioester hydrolase C-terminal domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
Signal transduction histidine kinase internal region
PBCV-specific basic adaptor domain-containing protein
Tat (Twin-arginine translocation) pathway signal sequence containing protein
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
SusD/RagB family nutrient-binding outer membrane lipoprotein
Putative adhesin domain-containing protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Alpha-glycerophosphate oxidase C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
YMGG-like Gly-zipper domain-containing protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Right handed beta helix domain-containing protein
N-acetylneuraminic acid synthase N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Aminoacyl-transfer RNA synthetases class-II family profile
Carbamoyl-phosphate synthase small subunit N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glycoside hydrolase family 42 N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Reversibly protonated during proton transport
Fibronectin type-III domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyrroline-5-carboxylate reductase dimerisation
Rhamnogalacturonan I lyase beta-sheet domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
General stress protein FMN-binding split barrel
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
Carboxypeptidase-like regulatory domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
Saccharopine dehydrogenase-like C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Alpha-D-phosphohexomutase alpha/beta/alpha
N6 adenine-specific DNA methyltransferase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Type I restriction enzyme R protein N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phosphoribosylformylglycinamidine synthase linker
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
3-hydroxyacyl-CoA dehydrogenase C-terminal
Heme-copper oxidase subunit III family profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Phospholipase C/D domain-containing protein
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Type IX secretion system membrane protein PorP/SprF
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Integral membrane protein YccS N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glutathionylspermidine synthase pre-ATP-grasp-like
Oligogalacturonate lyase domain-containing protein
Positions MEP for the nucleophilic attack
Inner membrane protein YgaP-like transmembrane
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Translation elongation factor EFTs/EF1B dimerisation
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Cytochrome b561 bacterial/Ni-hydrogenase
Gly-cisPro motif, important for rejection of L-amino acids
3-hydroxyacyl-CoA dehydrogenase NAD binding
Proton acceptor; for glutaminase activity
Phosphatidate phosphatase APP1 catalytic
Inward rectifier potassium channel C-terminal
NIF system FeS cluster assembly NifU C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
AB hydrolase-1 domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Sphingolipid delta4-desaturase N-terminal
Small ribosomal subunit protein uS4 N-terminal
DNA topoisomerase I catalytic core eukaryotic-type
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
ABC-type uncharacterised transport system
Glucose/Sorbosone dehydrogenase domain-containing protein
Translation elongation factor P/YeiP central
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Lipocalin-like domain-containing protein
Alpha-2-macroglobulin domain-containing protein
Large ribosomal subunit protein bL9 C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Bacterial surface antigen (D15) domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Prokaryotic-type class I peptide chain release factors
Peptidase M14 carboxypeptidase A domain-containing protein
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Transcription elongation factor GreA/GreB C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Conserved virulence factor B-like winged helix
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Fibronectin type III-like domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein uL15/eL18
TonB-dependent receptor plug domain-containing protein
Biopterin-dependent aromatic amino acid hydroxylase family profile
DNA mismatch repair proteins mutS family
Release factor glutamine methyltransferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Shikimate dehydrogenase substrate binding N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Schiff-base intermediate with acetaldehyde
Amidohydrolase-related domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Type IX secretion system protein PorV domain-containing protein
Histidine kinase domain-containing protein
Tetrahydrodipicolinate-N-succinyltransferase chain A
Exonuclease VII large subunit C-terminal
Anthranilate synthase component I N-terminal
Mannose-6-phosphate isomerase type II C-terminal
PsbP C-terminal domain-containing protein
Serine aminopeptidase S33 domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Aromatic hydrocarbon degradation protein
Transcription elongation factor GreA/GreB N-terminal
Bacterial transcription activator effector binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Putative oxidoreductase/dehydrogenase Rossmann-like
TonB C-terminal domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
PLD phosphodiesterase domain-containing protein
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Chromosomal replication initiator DnaA C-terminal
Transposase IS116/IS110/IS902 C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
RNA binding; important for wobble base 34 recognition
Polymerase/histidinol phosphatase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Pseudouridine synthase I TruA alpha/beta
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
NADH:ubiquinone oxidoreductase chain 4 N-terminal
YVTN family beta-propeller domain-containing protein
Peptidase M43 pregnancy-associated plasma-A
Peptidase M43 pregnancy-associated plasma-A domain-containing protein
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
VPDSG-CTERM protein sorting domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Homogentisate 1,2-dioxygenase N-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Thymidylate synthase/dCMP hydroxymethylase
SusE outer membrane protein domain-containing protein
DNA-directed DNA polymerase family A palm
Alanyl-transfer RNA synthetases family profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal