Dihydroneopterin aldolase MtpD C-terminal
Tryptophan synthase beta chain-like PALP
DNA polymerase alpha/delta/epsilon subunit B
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Bacterial type II secretion system protein E
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
6-hydroxymethylpterin diphosphokinase MptE-like
Probable transposase IS891/IS1136/IS1341
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Bacterial bifunctional deaminase-reductase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Heme-copper oxidase subunit III family profile
MPBQ/MBSQ family SAM-binding methyltransferase profile
Schiff-base intermediate with acetaldehyde
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Alpha-D-phosphohexomutase alpha/beta/alpha
Mandelate racemase/muconate lactonizing enzyme C-terminal
Archaeal glycosylation protein B peripheral
Polymerase/histidinol phosphatase N-terminal
Pseudouridine synthase I TruA alpha/beta
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Major facilitator superfamily (MFS) profile
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Could be important to modulate the pK values of the two catalytic cysteine residues
Phosphoadenosine phosphosulphate reductase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Carbamoyl-phosphate synthase small subunit N-terminal
6-phosphogluconate dehydrogenase C-terminal
DR2241 4Fe-4S iron-sulfur cluster binding
Large ribosomal subunit protein uL10-like insertion
DNA mismatch repair proteins mutS family
Small zinc finger protein HVO-2753-like zinc-binding pocket
Helix-hairpin-helix DNA-binding motif class 1
Peptidase S9 prolyl oligopeptidase catalytic
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycosyltransferase subfamily 4-like N-terminal
Plays an important role in substrate specificity
NADH:ubiquinone oxidoreductase 30kDa subunit
Exonuclease VII large subunit C-terminal
NIF system FeS cluster assembly NifU C-terminal
Water stress and hypersensitive response
YbaK/aminoacyl-tRNA synthetase-associated
Bacterioopsin transcriptional activator GAF and HTH associated
Small ribosomal subunit protein eS4 N-terminal
Small ribosomal subunit protein eS4 central region
Archaetidylserine decarboxylase alpha chain
Archaetidylserine decarboxylase beta chain
Cleavage (non-hydrolytic); by autocatalysis
Schiff-base intermediate with substrate; via pyruvic acid
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Large ribosomal subunit protein uL15/eL18
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DNA-directed DNA polymerase family B multifunctional
Periplasmic copper-binding protein NosD beta helix
Nitrite/Sulfite reductase ferredoxin-like
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Transcription factor NikR nickel binding C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Shikimate dehydrogenase substrate binding N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Glycosyl transferase family 3 N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Sodium/calcium exchanger membrane region
Peptide methionine sulphoxide reductase MsrA
Spo11/DNA topoisomerase VI subunit A N-terminal
DNA-directed RNA polymerase M/15kDa subunit
Siroheme decarboxylase AsnC-like ligand binding
Aminoacyl-transfer RNA synthetases class-II family profile
Quinolinate phosphoribosyl transferase C-terminal
Small ribosomal subunit protein uS15 N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ribosomal RNA adenine methylase transferase N-terminal
Cytochrome b/b6 N-terminal region profile
16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal
RNase L inhibitor RLI-like possible metal-binding
Glycine cleavage T-protein C-terminal barrel
Removed in mature form; by autocatalysis
Cytochrome b561 bacterial/Ni-hydrogenase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
ABC transporter substrate-binding protein PnrA-like
Large ribosomal subunit protein uL30-like ferredoxin-like fold
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Succinate dehydogenase/fumarate reductase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Alanyl-transfer RNA synthetases family profile
Actinobacteria/chloroflexi VLRF1 release factor
NIF system FeS cluster assembly NifU N-terminal
SUF system FeS cluster assembly SufBD N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Aconitase A/isopropylmalate dehydratase small subunit swivel
DNA-directed RNA polymerase subunit 2 hybrid-binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
SAM-dependent methyltransferase TRM5/TYW2-type
Electron transfer via tryptophanyl radical
Survival protein SurE-like phosphatase/nucleotidase
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Cobalamin-independent methionine synthase MetE N-terminal
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Transcription factor CBF/NF-Y/archaeal histone
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
DNA-directed DNA polymerase family B exonuclease
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Inosine monophosphate cyclohydrolase-like
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL2 C-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Sodium symporter small subunit predicted
DNA-directed RNA polymerase RBP11-like dimerisation
Cytochrome b/b6 C-terminal region profile
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Anti-bacteriophage protein A/HamA C-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
Schiff-base intermediate with dihydroxyacetone-P
Ribose-phosphate pyrophosphokinase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
TRAP C4-dicarboxylate transport system permease DctM subunit
RNA polymerase subunit H/Rpb5 C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Signal recognition particle SRP54 helical bundle
Phosphoribosylformylglycinamidine synthase linker
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Polysaccharide biosynthesis protein C-terminal
Prepilin type IV endopeptidase peptidase
tRNA nucleotidyltransferase substrate binding
RNA 3'-terminal phosphate cyclase insert
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal