Heme-copper oxidase subunit III family profile
Mandelate racemase/muconate lactonizing enzyme C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Cation-transporting P-type ATPase N-terminal
Major facilitator superfamily (MFS) profile
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Lipocalin-like domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
RND efflux pump membrane fusion protein barrel-sandwich
TonB-dependent receptor-like beta-barrel
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Peptidase M14 carboxypeptidase A domain-containing protein
Mannose-6-phosphate isomerase type II C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Outer membrane protein beta-barrel domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Polymerase/histidinol phosphatase N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Helix-hairpin-helix DNA-binding motif class 1
Phosphodiester glycosidase domain-containing protein
N6 adenine-specific DNA methyltransferase N-terminal
Putative auto-transporter adhesin head GIN
Transcription elongation factor GreA/GreB C-terminal
Tryptophan synthase beta chain-like PALP
NADH:flavin oxidoreductase/NADH oxidase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
RagB/SusD family nutrient uptake outer membrane protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
TonB-dependent receptor plug domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Could be important to modulate the pK values of the two catalytic cysteine residues
Peptidase S9 prolyl oligopeptidase catalytic
4'-phosphopantetheinyl transferase N-terminal
Peptide methionine sulphoxide reductase MsrA
Polysaccharide biosynthesis protein C-terminal
Peptidase S8/S53 domain-containing protein
Type I restriction enzyme R protein N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Anthranilate synthase component I N-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Integral membrane protein YccS N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Curli production assembly/transport component CsgF
Type IX secretion system PorP/SprF family membrane protein
Pyruvate phosphate dikinase AMP/ATP-binding
L,D-transpeptidase catalytic domain-containing protein
Beta-xylosidase C-terminal Concanavalin A-like
Sodium/calcium exchanger membrane region
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
SGNH hydrolase-type esterase domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycosyltransferase subfamily 4-like N-terminal
Important for beta-aspartyl-AMP intermediate formation
Glycoside hydrolase GH146 substrate-binding
Large ribosomal subunit protein uL2 C-terminal
Membrane fusion protein biotin-lipoyl like
Type IX secretion system membrane protein PorP/SprF
Penicillin-binding protein transpeptidase
Type I restriction modification DNA specificity
Beta-lactamase class A catalytic domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Signal transduction histidine kinase internal region
Translation elongation factor P/YeiP central
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Sialate O-acetylesterase domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
DNA-directed DNA polymerase family A palm
UDP N-acetylglucosamine O-acyltransferase C-terminal
Glycosyl hydrolase family 13 catalytic domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Schiff-base intermediate with acetaldehyde
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
LPS export ABC transporter periplasmic protein LptC
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Gliding motility-associated lipoprotein GldH
Quercetin 2,3-dioxygenase C-terminal cupin
Alginate export domain-containing protein
Putative auto-transporter adhesin head GIN domain-containing protein
Secreted protein (Por secretion system target)
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
TonB-linked SusC/RagA family outer membrane protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Two component regulator with propeller domain
Polysaccharide biosynthesis protein CapD-like
Release factor glutamine methyltransferase N-terminal
Transcription elongation factor GreA/GreB N-terminal
Glycine cleavage T-protein C-terminal barrel
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Proton acceptor; for glutaminase activity
Pyrroline-5-carboxylate reductase dimerisation
Chromosomal replication initiator DnaA C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
SusC/RagA family TonB-linked outer membrane protein
General stress protein FMN-binding split barrel
Secretion system C-terminal sorting domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gylcosyl hydrolase 115 C-terminal domain-containing protein
Conserved virulence factor B-like winged helix
Cysteine sulfenic acid (-SOH) intermediate
Alpha-2-macroglobulin domain-containing protein
NAD(P) transhydrogenase alpha subunit C-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Alanyl-transfer RNA synthetases family profile
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Urease accessory protein UreH-like transmembrane
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
NADH:ubiquinone oxidoreductase 30kDa subunit
Positions MEP for the nucleophilic attack
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Carboxypeptidase-like regulatory domain-containing protein
Aconitase A/isopropylmalate dehydratase small subunit swivel
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Plays an important role in discriminating NADH against NADPH
NIF system FeS cluster assembly NifU C-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Glycosyl transferase family 3 N-terminal
Small ribosomal subunit protein uS4 N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
RNA binding; important for wobble base 34 recognition
GTA TIM-barrel-like domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Shikimate dehydrogenase substrate binding N-terminal
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Saccharopine dehydrogenase-like C-terminal
DNA replication/recombination mediator RecO N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Beta-lactamase-related domain-containing protein
Biopterin-dependent aromatic amino acid hydroxylase family profile
Chitobiase/beta-hexosaminidases N-terminal
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
S-adenosylmethionine-dependent methyltransferase
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Peptide methionine sulfoxide reductase MsrA
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Alpha galactosidase C-terminal beta sandwich
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Prokaryotic glutathione synthetase ATP-binding
Outer membrane protein transport protein (OMPP1/FadL/TodX)
Peptidase M1 membrane alanine aminopeptidase
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Large ribosomal subunit protein uL15/eL18
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Lipocalin/cytosolic fatty-acid binding domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Cell wall-active antibiotics response LiaF-like C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
NADH:ubiquinone oxidoreductase-like 20kDa subunit
DNA topoisomerase I catalytic core eukaryotic-type
Glucosamine/galactosamine-6-phosphate isomerase
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
DNA mismatch repair proteins mutS family
T9SS C-terminal target domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Transition state stabilizer; via amide nitrogen
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Beta-hexosaminidase bacterial type N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Glycosyl-hydrolase 97 C-terminal oligomerisation
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
RNA 2-O ribose methyltransferase substrate binding
Peptide methionine sulfoxide reductase MsrB
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Heavy metal binding domain-containing protein
Glutathionylspermidine synthase pre-ATP-grasp-like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Solute-binding protein family 3/N-terminal
Xylose isomerase-like TIM barrel domain-containing protein
SusD/RagB family nutrient-binding outer membrane lipoprotein
Iron dependent repressor metal binding and dimerisation
Translation elongation factor EFTs/EF1B dimerisation
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Formamidopyrimidine-DNA glycosylase catalytic
Homogentisate 1,2-dioxygenase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Acetyl xylan esterase domain-containing protein
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Prokaryotic-type class I peptide chain release factors
Pyrimidine nucleoside phosphorylase C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Replication-associated protein G2P N-terminal
Tellurite resistance methyltransferase TehB-like
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
ATP-grasp fold succinyl-CoA synthetase-type
Trigger factor ribosome-binding bacterial
Phosphoadenosine phosphosulphate reductase
tRNA pseudouridylate synthase B C-terminal
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
NIF system FeS cluster assembly NifU N-terminal
Reversibly protonated during proton transport
Tetrahydrodipicolinate-N-succinyltransferase chain A