Cyclophilin-like domain-containing protein
TonB-dependent receptor-like beta-barrel
Beta-lactamase-related domain-containing protein
3-keto-disaccharide hydrolase domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Neutral/alkaline non-lysosomal ceramidase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Polysaccharide chain length determinant N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Cellulose-binding Sde182 nucleoside hydrolase-like
SusD/RagB family nutrient-binding outer membrane lipoprotein
Major facilitator superfamily (MFS) profile
Pyrroline-5-carboxylate reductase catalytic N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Large ribosomal subunit protein uL2 C-terminal
Glycoside hydrolase family 13 N-terminal
Lipocalin-like domain-containing protein
NIF system FeS cluster assembly NifU C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Tryptophan synthase beta chain-like PALP
Alanyl-transfer RNA synthetases family profile
DNA topoisomerase I catalytic core eukaryotic-type
Gfo/Idh/MocA-like oxidoreductase C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Mandelate racemase/muconate lactonizing enzyme C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Carbamoyl-phosphate synthase small subunit N-terminal
TonB C-terminal domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Gliding motility-associated C-terminal domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
PBCV-specific basic adaptor domain-containing protein
Lipoprotein SmpA/OmlA domain-containing protein
N-sulphoglucosamine sulphohydrolase C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Peptidase M1 membrane alanine aminopeptidase
ATP-grasp fold succinyl-CoA synthetase-type
Inner membrane protein YgaP-like transmembrane
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
SGNH hydrolase-type esterase domain-containing protein
Curlin associated repeat-containing protein
Small ribosomal subunit protein uS4 N-terminal
Penicillin-binding protein transpeptidase
Signal transduction histidine kinase internal region
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Tail specific protease domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Polysaccharide biosynthesis protein C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Gluconate 2-dehydrogenase subunit 3 family protein
Thiamin pyrophosphokinase thiamin-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Peptidase M14 carboxypeptidase A domain-containing protein
Calcium/calmodulin-dependent protein kinase II association-domain domain-containing protein
Membrane fusion protein biotin-lipoyl like
Gamma-glutamylcyclotransferase AIG2-like
Fibronectin type-III domain-containing protein
Chlamydial protease/proteasome-like activity factor PDZ
Glycosyltransferase subfamily 4-like N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Activator of Hsp90 ATPase homologue 1-like C-terminal
Inosine/uridine-preferring nucleoside hydrolase
Conserved virulence factor B-like winged helix
Phosphatidic acid phosphatase type 2/haloperoxidase
tRNA pseudouridylate synthase B C-terminal
General stress protein FMN-binding split barrel
Secretion system C-terminal sorting domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Thiopeptide-type bacteriocin biosynthesis
Anthranilate synthase component I N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Antitoxin Xre/MbcA/ParS-like toxin-binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Oxidoreductase molybdopterin-binding domain-containing protein
SD-repeat containing protein B domain-containing protein
Type I restriction enzyme R protein N-terminal
Phage terminase large subunit C-terminal
Phage terminase large subunit N-terminal
Beta-hexosaminidase bacterial type N-terminal
peptide-methionine (R)-S-oxide reductase
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
RNA polymerase sigma factor 70 region 4 type 2
Carboxypeptidase regulatory-like domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Histidine kinase domain-containing protein
Lysidine-tRNA(Ile) synthetase C-terminal
Large ribosomal subunit protein uL6 alpha-beta
DNA mismatch repair proteins mutS family
Homogentisate 1,2-dioxygenase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glycine cleavage T-protein C-terminal barrel
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Integral membrane protein YccS N-terminal
Positions MEP for the nucleophilic attack
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Peptidase C14 caspase domain-containing protein
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Pyruvate phosphate dikinase AMP/ATP-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Heme-copper oxidase subunit III family profile
Beta-lactamase class A catalytic domain-containing protein
Translation elongation factor EFTs/EF1B dimerisation
Gliding motility protein SprA N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-118)
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Type 1 periplasmic binding fold superfamily protein
Moybdenum cofactor oxidoreductase dimerisation
Peptidase M43 pregnancy-associated plasma-A
Glucosamine/galactosamine-6-phosphate isomerase
Alpha-D-phosphohexomutase alpha/beta/alpha
SUF system FeS cluster assembly SufBD N-terminal
Copper type II ascorbate-dependent monooxygenase C-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Cationic amino acid transporter C-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Proton acceptor; for glutaminase activity
Glutathionylspermidine synthase pre-ATP-grasp-like
Pseudouridine synthase I TruA alpha/beta
AMP-activated protein kinase glycogen-binding
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Thiamine pyrophosphate enzyme TPP-binding
Haem-binding uptake Tiki superfamily ChaN
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Aconitase A/isopropylmalate dehydratase small subunit swivel
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
RagB/SusD family nutrient uptake outer membrane protein
Pectate lyase superfamily protein domain-containing protein
Urease accessory protein UreH-like transmembrane
Alpha-glycerophosphate oxidase C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Gly-cisPro motif, important for rejection of L-amino acids
Plays an important role in substrate specificity
Phosphomannose isomerase type I catalytic
ATP synthase F1 complex delta/epsilon subunit N-terminal
Trigger factor ribosome-binding bacterial
Electron transfer via tryptophanyl radical
Phosphoadenosine phosphosulphate reductase
Saccharopine dehydrogenase-like C-terminal
Prokaryotic-type class I peptide chain release factors
Xylose isomerase-like TIM barrel domain-containing protein
Large ribosomal subunit protein uL15/eL18
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Curli production assembly/transport component CsgF
T9SS type A sorting domain-containing protein
Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Cobalamin-independent methionine synthase MetE N-terminal
PhoD-like phosphatase metallophosphatase
Peptide methionine sulphoxide reductase MsrA
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Cytochrome C biogenesis protein transmembrane
Thiol:disulfide interchange protein DsbD N-terminal
Release factor glutamine methyltransferase N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
40-residue YVTN family beta-propeller repeat protein
Membrane insertase YidC/Oxa/ALB C-terminal
Type IX secretion system protein PorV domain-containing protein
Important for interaction with partner proteins
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Polysaccharide biosynthesis protein CapD-like
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Chitobiase/beta-hexosaminidases N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
NADH:flavin oxidoreductase/NADH oxidase N-terminal
RNA binding; important for wobble base 34 recognition
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Molybdopterin cofactor biosynthesis C (MoaC)
O-(3'-phospho-DNA)-tyrosine intermediate
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Right handed beta helix domain-containing protein
Calcineurin-like phosphoesterase domain-containing protein
Putative oxidoreductase/dehydrogenase Rossmann-like
Peptide methionine sulfoxide reductase MsrA
S-adenosylmethionine-dependent methyltransferase
N-end rule aminoacyl transferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Essential for prephenate dehydratase activity
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Putative exodeoxyribonuclease 8 PDDEXK-like
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Phosphoribosylformylglycinamidine synthase linker
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
TtsA-like Glycoside hydrolase family 108
Restriction system protein Mrr-like N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycoside hydrolase GH146 substrate-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Bacterial transcription activator effector binding
Cell division protein FtsQ/DivIB C-terminal
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Beta-galactosidase trimerisation domain-containing protein
Carboxypeptidase-like regulatory domain-containing protein
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
O-(5'-phospho-DNA)-tyrosine intermediate
Aromatic amino acid beta-eliminating lyase/threonine aldolase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Aromatic hydrocarbon degradation membrane protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Water stress and hypersensitive response
Formamidopyrimidine-DNA glycosylase catalytic
Glycosyl-hydrolase 97 C-terminal oligomerisation
DNA replication/recombination mediator RecO N-terminal
Glycosyl transferase family 3 N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Curli production assembly/transport component CsgE
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Schiff-base intermediate with acetaldehyde
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Pyrroline-5-carboxylate reductase dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aminoacyl-tRNA synthetase class I anticodon-binding
AraC-type arabinose-binding/dimerisation
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Translation elongation factor P/YeiP central
Inward rectifier potassium channel C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Phosphatidate phosphatase APP1 catalytic
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Putative adhesin domain-containing protein
Putative beta-lactamase-inhibitor-like PepSY-like
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Cytochrome b561 bacterial/Ni-hydrogenase
RlpA-like protein double-psi beta-barrel
Cytochrome b561 domain-containing protein
High potential iron-sulfur proteins family profile
ABC-type uncharacterised transport system
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Chromosomal replication initiator DnaA C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
DNA-directed DNA polymerase family A palm