Major facilitator superfamily (MFS) profile
Exonuclease VII large subunit C-terminal
TonB-dependent receptor-like beta-barrel
Peptidase S9 prolyl oligopeptidase catalytic
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Cysteine sulfenic acid (-SOH) intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
S-adenosyl-L-homocysteine hydrolase NAD binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Glycosyl hydrolases family 2 sugar binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Disulphide bond isomerase DsbC/G N-terminal
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
RlpA-like protein double-psi beta-barrel
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Glucan biosynthesis periplasmic MdoG C-terminal
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Glycosyltransferase subfamily 4-like N-terminal
Signal transduction histidine kinase dimerisation/phosphoacceptor
Hydroquinone 1,2-dioxygenase large subunit N-terminal
Penicillin-binding protein transpeptidase
Essential for prephenate dehydratase activity
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Bacterial type II secretion system protein E
Poly-beta-hydroxybutyrate polymerase N-terminal
Polysaccharide biosynthesis protein C-terminal
Glycoside hydrolase family 42 N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Endolytic peptidoglycan transglycosylase RlpA
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Membrane fusion protein biotin-lipoyl like
Translation elongation factor P/YeiP central
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Acyl-CoA dehydrogenase/oxidase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Outer membrane protein assembly factor BamD
N-end rule aminoacyl transferase C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein
Phosphoribosylformylglycinamidine synthase linker
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
AraC-type arabinose-binding/dimerisation
Type IV secretion system coupling protein TraD DNA-binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Solute-binding protein family 3/N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Large ribosomal subunit protein uL6 alpha-beta
Terminase large subunit gp17-like C-terminal
Polypeptide-transport-associated ShlB-type
RNA polymerase sigma factor 70 region 4 type 2
Signal recognition particle SRP54 helical bundle
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Heavy metal-binding domain-containing protein
Molybdopterin cofactor biosynthesis C (MoaC)
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Alanyl-transfer RNA synthetases family profile
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycosyl hydrolase family 98 putative carbohydrate-binding module
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
O-(5'-phospho-DNA)-tyrosine intermediate
Antitoxin Xre/MbcA/ParS-like toxin-binding
Flagellar motor switch protein FliN-like C-terminal
Putative auto-transporter adhesin head GIN
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Heme-copper oxidase subunit III family profile
Tetrahydrodipicolinate-N-succinyltransferase chain A
Pseudouridine synthase I TruA alpha/beta
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase-like C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
YbgF trimerisation domain-containing protein
Gamma-glutamylcyclotransferase AIG2-like
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
O-(3'-phospho-DNA)-tyrosine intermediate
TonB-dependent receptor plug domain-containing protein
Prepilin type IV endopeptidase peptidase
Putative regulatory protein FmdB Zinc ribbon
Glycosyl transferase family 28 C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Plays an important role in substrate specificity
Tryptophan synthase beta chain-like PALP
DNA-directed DNA polymerase family A palm
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Type I restriction enzyme HindI endonuclease subunit-like C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Aminoacyl-transfer RNA synthetases class-II family profile
Glucose-methanol-choline oxidoreductase N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Saccharopine dehydrogenase-like C-terminal
Glycosyltransferase family 28 N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Probable periplasmic serine endoprotease DegP-like
Superoxide dismutase copper/zinc binding
Methionyl-tRNA synthetase anticodon-binding
Acetyl-CoA dehydrogenase-like C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
DNA topoisomerase I catalytic core eukaryotic-type
Resolvase/invertase-type recombinase catalytic
Heat-inducible transcription repressor HrcA C-terminal
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
Peptide methionine sulphoxide reductase MsrA
Flagellar assembly protein FliH/Type III secretion system HrpE
ABC-type transport auxiliary lipoprotein component
NADH:flavin oxidoreductase/NADH oxidase N-terminal
CobB/CobQ-like glutamine amidotransferase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Histidine-specific methyltransferase SAM-dependent
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-100)
S-adenosylmethionine-dependent methyltransferase
DNA mismatch repair proteins mutS family
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Peptidase M1 membrane alanine aminopeptidase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Polymerase/histidinol phosphatase N-terminal
Beta-lactamase-related domain-containing protein
Putative oxidoreductase/dehydrogenase Rossmann-like
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
General stress protein FMN-binding split barrel
Proton acceptor; for glutaminase activity
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Peptide methionine sulfoxide reductase MsrA
Important for beta-aspartyl-AMP intermediate formation
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
ATP synthase F1 complex delta/epsilon subunit N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Putative exodeoxyribonuclease 8 PDDEXK-like
PhoD-like phosphatase metallophosphatase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glucosamine/galactosamine-6-phosphate isomerase
Right handed beta helix domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Polysaccharide chain length determinant N-terminal
Glycine cleavage T-protein C-terminal barrel
Cobaltochelatase subunit CobS N-terminal
Rap1a immunity protein domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
TtsA-like Glycoside hydrolase family 108
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Interaction with polymerase core subunit RpoC
Anthranilate synthase component I N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Putative Flp pilus-assembly TadG-like N-terminal
Sodium/calcium exchanger membrane region
Chromosomal replication initiator DnaA C-terminal
Nitrite/Sulfite reductase ferredoxin-like
N6 adenine-specific DNA methyltransferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Prokaryotic-type class I peptide chain release factors
YbaK/aminoacyl-tRNA synthetase-associated
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Outer membrane protein beta-barrel domain-containing protein
Important for autoinhibition of adenylyltransferase activity
Release factor glutamine methyltransferase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Transposase IS116/IS110/IS902 C-terminal
Spore coat protein U domain-containing protein
Alpha-glycerophosphate oxidase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Membrane protein 6-pyruvoyl-tetrahydropterin synthase-related
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Organic solvent tolerance-like N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DNA replication/recombination mediator RecO N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Dienelactone hydrolase domain-containing protein
Acyl-CoA dehydrogenase N-terminal bacteria
Ribosomal RNA adenine methylase transferase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
RNA binding; important for wobble base 34 recognition
Helix-hairpin-helix DNA-binding motif class 1
Cob(I)alamin adenosyltransferase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Large ribosomal subunit protein uL2 C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Glycosyl transferase family 3 N-terminal
Glycoside hydrolase family 31 N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
BREX system Lon protease-like BrxL N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Pili assembly chaperone N-terminal domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type