Gram-positive cocci surface proteins LPxTG domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein uL6 alpha-beta
Plays an important role in substrate specificity
CobB/CobQ-like glutamine amidotransferase
Sporulation transcription regulator WhiA N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Inner membrane protein YgaP-like transmembrane
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
BAAT/Acyl-CoA thioester hydrolase C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Reversibly protonated during proton transport
Helix-hairpin-helix DNA-binding motif class 1
Glycosyltransferase subfamily 4-like N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Trigger factor ribosome-binding bacterial
Type II secretion system protein GspF domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cytochrome C biogenesis protein transmembrane
N6 adenine-specific DNA methyltransferase N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Major facilitator superfamily (MFS) profile
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
ABC-type glycine betaine transport system substrate-binding domain-containing protein
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
RNA 2-O ribose methyltransferase substrate binding
Phosphocysteine intermediate; for EIIB activity
Cysteine sulfenic acid (-SOH) intermediate
Translation elongation factor P/YeiP central
TAXI family TRAP transporter solute-binding subunit
Peptidase M1 membrane alanine aminopeptidase
Important for beta-aspartyl-AMP intermediate formation
O-(5'-phospho-DNA)-tyrosine intermediate
L,D-transpeptidase catalytic domain-containing protein
Fe/B12 periplasmic-binding domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Solute-binding protein family 5 domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Thymidylate synthase/dCMP hydroxymethylase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Phosphatidic acid phosphatase type 2/haloperoxidase
Heat-inducible transcription repressor HrcA C-terminal
Essential for prephenate dehydratase activity
Resolvase/invertase-type recombinase catalytic
O-(3'-phospho-DNA)-tyrosine intermediate
Polymerase/histidinol phosphatase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
6-phosphogluconate dehydrogenase C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Penicillin-binding protein transpeptidase
RNA polymerase sigma factor 70 region 4 type 2
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Alanyl-transfer RNA synthetases family profile
Formamidopyrimidine-DNA glycosylase catalytic
Carbohydrate-binding domain-containing protein
Bacterial Ig-like domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein uL15/eL18
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Phenol hydroxylase C-terminal dimerisation
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Important for substrate specificity; cannot use PPi as phosphoryl donor
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
DNA replication/recombination mediator RecO N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Pyruvate dehydrogenase E1 component middle
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Inosine/uridine-preferring nucleoside hydrolase
YbaK/aminoacyl-tRNA synthetase-associated
SsuA/THI5-like domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Methionine ABC transporter substrate-binding protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Tryptophan synthase beta chain-like PALP
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Phosphomannose isomerase type I catalytic
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
RNA binding; important for wobble base 34 recognition
4'-phosphopantetheinyl transferase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Type I restriction modification DNA specificity
Cytochrome b/b6 N-terminal region profile
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
Resuscitation-promoting factor core lysozyme-like domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Phosphotransferase system enzyme I N-terminal
Small ribosomal subunit protein uS4 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Aminoacyl-tRNA synthetase class I anticodon-binding
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
Schiff-base intermediate with acetaldehyde
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Release factor glutamine methyltransferase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Peptidase S9 prolyl oligopeptidase catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Alpha-D-phosphohexomutase alpha/beta/alpha
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Membrane fusion protein biotin-lipoyl like
Ribosome maturation factor RimP N-terminal
Anthranilate synthase component I N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Interaction with polymerase core subunit RpoC