Aminoacyl-transfer RNA synthetases class-II family profile
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Myo-inositol-1-phosphate synthase GAPDH-like
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
RNA binding; important for wobble base 34 recognition
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Major facilitator superfamily (MFS) profile
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Translation elongation factor P/YeiP central
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
6-phosphogluconate dehydrogenase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Shikimate dehydrogenase substrate binding N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Putative exodeoxyribonuclease 8 PDDEXK-like
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Phosphomannose isomerase type I catalytic
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Sporulation transcription regulator WhiA N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
S-adenosyl-L-homocysteine hydrolase NAD binding
Ribosomal RNA adenine methylase transferase N-terminal
Thiamin pyrophosphokinase thiamin-binding
Essential for prephenate dehydratase activity
DNA-directed DNA polymerase family A palm
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
RNA polymerase sigma factor 70 region 4 type 2
Glycoside hydrolase family 42 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Penicillin-binding protein transpeptidase
Tryptophan synthase beta chain-like PALP
Alpha-L-rhamnosidase six-hairpin glycosidase
Peptidase S9 prolyl oligopeptidase catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Transcription regulator AsnC/Lrp ligand binding
Peptidase M1 membrane alanine aminopeptidase
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
O-(5'-phospho-DNA)-tyrosine intermediate
Proton acceptor; for glutaminase activity
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
O-(3'-phospho-DNA)-tyrosine intermediate
tRNA pseudouridylate synthase B C-terminal
NIF system FeS cluster assembly NifU N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Polymerase/histidinol phosphatase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Anthranilate synthase component I N-terminal
Small ribosomal subunit protein uS4 N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Helix-hairpin-helix DNA-binding motif class 1
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glycosyl transferase family 3 N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Release factor glutamine methyltransferase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Chromosomal replication initiator DnaA C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Putative Flp pilus-assembly TadG-like N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Important for beta-aspartyl-AMP intermediate formation
Interaction with polymerase core subunit RpoC
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Membrane iron-sulfur containing protein FtrD-like
Thymidylate synthase/dCMP hydroxymethylase
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Protein O-mannosyl-transferase C-terminal four TM
Pyridoxamine 5'-phosphate oxidase putative
DNA replication/recombination mediator RecO N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Large ribosomal subunit protein uL2 C-terminal
Pseudouridine synthase I TruA alpha/beta
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Gram-positive cocci surface proteins LPxTG
Type I restriction modification DNA specificity
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Plays an important role in substrate specificity
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Putative regulatory protein FmdB Zinc ribbon
Membrane insertase YidC/Oxa/ALB C-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
RNA 2-O ribose methyltransferase substrate binding
Glycoside hydrolase family 31 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein uL15/eL18
Reversibly protonated during proton transport
Phosphatidic acid phosphatase type 2/haloperoxidase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Alanyl-transfer RNA synthetases family profile
Gly-cisPro motif, important for rejection of L-amino acids
Anti-bacteriophage protein A/HamA C-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Inosine/uridine-preferring nucleoside hydrolase
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Methionyl-tRNA synthetase anticodon-binding