Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Pyruvate phosphate dikinase AMP/ATP-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
RNA polymerase sigma factor 54 DNA-binding
Prokaryotic-type class I peptide chain release factors
Peptidase MA-like domain-containing protein
Resolvase/invertase-type recombinase catalytic
Schiff-base intermediate with substrate; via pyruvic acid
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Pseudouridine synthase I TruA alpha/beta
SUF system FeS cluster assembly SufBD N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Peptidase S9 prolyl oligopeptidase catalytic
Large ribosomal subunit protein uL15/eL18
Pyruvate/ketoisovalerate oxidoreductase catalytic
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Chromosomal replication initiator DnaA C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Release factor glutamine methyltransferase N-terminal
Major facilitator superfamily (MFS) profile
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
DNA-directed DNA polymerase family A palm
Exonuclease VII large subunit C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Formiminotransferase C-terminal subdomain
Formiminotransferase N-terminal subdomain
Dinitrogenase iron-molybdenum cofactor biosynthesis
Outer membrane protein beta-barrel domain-containing protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Molybdopterin cofactor biosynthesis C (MoaC)
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Plays an important role in substrate specificity
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Solute-binding protein family 5 domain-containing protein
Na+/H+ antiporter MnhB subunit-related protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Bacterial transcription activator effector binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
t-SNARE coiled-coil homology domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Sigma 54 modulation/S30EA ribosomal protein C-terminal
ABC transporter substrate-binding protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Thiamine pyrophosphate enzyme TPP-binding
2,4-diaminopentanoate dehydrogenase C-terminal
Dihydrodipicolinate reductase N-terminal
Peptidase M1 membrane alanine aminopeptidase
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Tryptophan synthase beta chain-like PALP
Alpha-D-phosphohexomutase alpha/beta/alpha
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Fibronectin type-III domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
ABC transporter substrate-binding protein PnrA-like
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Positions MEP for the nucleophilic attack
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Bacterial DNA polymerase III alpha subunit NTPase
Aldehyde ferredoxin oxidoreductase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Polymerase/histidinol phosphatase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Damage-control phosphatase ARMT1-like metal-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Interchain (with Cys-209); in linked form
Interchain (with Cys-48); in linked form
Glycoside hydrolase family 31 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Prepilin type IV endopeptidase peptidase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
MucB/RseB N-terminal domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Membrane insertase YidC/Oxa/ALB C-terminal
Penicillin-binding protein transpeptidase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
RNA 2-O ribose methyltransferase substrate binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Translation elongation factor P/YeiP central
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
FAD-dependent oxidoreductase 2 FAD binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Calcineurin-like phosphoesterase domain-containing protein
Polysaccharide biosynthesis protein CapD-like
Proteinase inhibitor I42 chagasin domain-containing protein
Trigger factor ribosome-binding bacterial
Cell envelope-related transcriptional attenuator
Pyrimidine nucleoside phosphorylase C-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Secretin/TonB short N-terminal domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Sugar ABC transporter substrate-binding protein
RNA binding; important for wobble base 34 recognition
Helix-hairpin-helix DNA-binding motif class 1
Cycloisomaltooligosaccharide glucanotransferase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Phosphomannose isomerase type I catalytic
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Alanyl-transfer RNA synthetases family profile
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glycine cleavage T-protein C-terminal barrel
Bacterial type II secretion system protein E
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Proton acceptor; for glutaminase activity
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Putative glycogen debranching enzyme N-terminal
Reversibly protonated during proton transport
NIF system FeS cluster assembly NifU N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
RNA polymerase sigma factor 70 region 4 type 2
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Putative regulatory protein FmdB Zinc ribbon
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Polysaccharide chain length determinant N-terminal
Thiamin pyrophosphokinase thiamin-binding
Small ribosomal subunit protein uS4 N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal