RND efflux pump membrane fusion protein barrel-sandwich
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyruvate phosphate dikinase AMP/ATP-binding
O-(3'-phospho-DNA)-tyrosine intermediate
Formamidopyrimidine-DNA glycosylase catalytic
Solute-binding protein family 3/N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
NADH:ubiquinone oxidoreductase 30kDa subunit
Alpha-D-phosphohexomutase alpha/beta/alpha
Gamma-glutamylcyclotransferase AIG2-like
Glycosyltransferase subfamily 4-like N-terminal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Membrane fusion protein biotin-lipoyl like
N6 adenine-specific DNA methyltransferase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Glycoside hydrolase family 57 N-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Dinitrogenase iron-molybdenum cofactor biosynthesis
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Anthranilate synthase component I N-terminal
Reversibly protonated during proton transport
DNA replication/recombination mediator RecO N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Release factor glutamine methyltransferase N-terminal
Saccharopine dehydrogenase-like C-terminal
Ion-translocating oxidoreductase complex subunit B
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein uL2 C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
ABC transporter substrate-binding protein PnrA-like
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Flagellar basal-body/hook protein C-terminal
Pseudouridine synthase I TruA alpha/beta
HicB-like antitoxin of toxin-antitoxin system
tRNA (guanine-N(1)-)-methyltransferase C-terminal
Polymerase/histidinol phosphatase N-terminal
Major facilitator superfamily (MFS) profile
Carbamoyl-phosphate synthase small subunit N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
AB hydrolase-1 domain-containing protein
Damage-control phosphatase ARMT1-like metal-binding
Mannose-6-phosphate isomerase type II C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Tryptophan synthase beta chain-like PALP
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Glycosyl transferase family 28 C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Flagellar basal body rod protein N-terminal
Schiff-base intermediate with dihydroxyacetone-P
ABC-type glycine betaine transport system substrate-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Phospholipase/carboxylesterase/thioesterase domain-containing protein
Resolvase/invertase-type recombinase catalytic
Transglutaminase-like domain-containing protein
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
Thiamine pyrophosphate enzyme TPP-binding
Polypeptide-transport-associated ShlB-type
Type I restriction enzyme R protein N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Phosphatidic acid phosphatase type 2/haloperoxidase
Polysaccharide biosynthesis protein CapD-like
Cytochrome c-type biogenesis protein CcmF C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Pyruvate/ketoisovalerate oxidoreductase catalytic
Phospholipase C/D domain-containing protein
Small ribosomal subunit protein uS4 N-terminal
Protein-PII uridylyltransferase N-terminal
Trigger factor ribosome-binding bacterial
Flagellar motor switch protein FliN-like C-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Thiamine pyrophosphate enzyme N-terminal TPP-binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Nickel transport complex, NikM subunit, transmembrane
Aminoacyl-tRNA synthetase class I anticodon-binding
CobB/CobQ-like glutamine amidotransferase
Phosphotransferase system enzyme I N-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
L-seryl-tRNA selenium transferase N-terminal
Acetylserotonin O-methyltransferase dimerisation
Right handed beta helix domain-containing protein
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
S-adenosyl-L-homocysteine hydrolase NAD binding
Glutamate synthase alpha subunit C-terminal
Glycine cleavage T-protein C-terminal barrel
Survival protein SurE-like phosphatase/nucleotidase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Transcription factor NikR nickel binding C-terminal
Interaction with polymerase core subunit RpoC
RNA 2-O ribose methyltransferase substrate binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
PEP-CTERM protein-sorting domain-containing protein
Increases nucleophilicity of active site Cys
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Ribose-phosphate pyrophosphokinase N-terminal
N-acetylneuraminic acid synthase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Involved in ionization of N3 of dUMP, leading to its activation
Glucosamine/galactosamine-6-phosphate isomerase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Phosphoribosylformylglycinamidine synthase linker
Bacterial type II secretion system protein E
Gly-cisPro motif, important for rejection of L-amino acids
NIF system FeS cluster assembly NifU C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Peptidase S9 prolyl oligopeptidase catalytic
Important for beta-aspartyl-AMP intermediate formation
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Ribosomal RNA adenine methylase transferase N-terminal
Flagellar Assembly Protein A N-terminal region
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
TonB system biopolymer transport component
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Flagellar hook-length control protein-like C-terminal
Arginine decarboxylase C-terminal helical
Bacterial OB-fold domain-containing protein
DNA mismatch repair proteins mutS family
Type II restriction enzyme and methyltransferase RM.Eco57I-like
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Cysteine sulfenic acid (-SOH) intermediate
UDP N-acetylglucosamine O-acyltransferase C-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Trehalose-6-phosphate phosphatase helical bundle
Thioredoxin-like fold domain-containing protein
Shikimate dehydrogenase substrate binding N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Phosphoadenosine phosphosulphate reductase
O-(5'-phospho-DNA)-tyrosine intermediate
D,L-carboxypeptidase peptidase domain-containing protein
Chromosomal replication initiator DnaA C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Guanylate kinase/L-type calcium channel beta subunit
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NIF system FeS cluster assembly NifU N-terminal
Heme-copper oxidase subunit III family profile
6-hydroxymethylpterin diphosphokinase MptE-like
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Sodium/calcium exchanger membrane region
RsbT co-antagonist protein RsbRD N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Glycosyltransferase family 28 N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Translation elongation factor P/YeiP central
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Penicillin-binding protein transpeptidase
DNA-directed DNA polymerase family A palm
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Alanyl-transfer RNA synthetases family profile
Nitrite/Sulfite reductase ferredoxin-like
RNA polymerase sigma factor 70 region 4 type 2
Abortive infection protein-like C-terminal
ABC transporter substrate binding protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Putative regulatory protein FmdB Zinc ribbon
Type I restriction modification DNA specificity
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Polysaccharide chain length determinant N-terminal
Urease accessory protein UreH-like transmembrane
Large ribosomal subunit protein uL6 alpha-beta
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Outer membrane protein beta-barrel domain-containing protein
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
6-phosphogluconate dehydrogenase C-terminal
Plays an important role in substrate specificity
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Exonuclease VII large subunit C-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
F420-non-reducing hydrogenase iron-sulfur subunit D
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Large ribosomal subunit protein uL15/eL18
Flagella basal body P-ring formation protein FlgA C-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Ion-translocating oxidoreductase complex subunit G
Prepilin type IV endopeptidase peptidase
Homocysteine biosynthesis enzyme sulfur-incorporation
Signal recognition particle SRP54 helical bundle
Important for substrate specificity; cannot use PPi as phosphoryl donor
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal