non-reducing end alpha-L-arabinofuranosidase
Solute-binding protein family 3/N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Release factor glutamine methyltransferase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glucosamine/galactosamine-6-phosphate isomerase
Major facilitator superfamily (MFS) profile
N,N-dimethylformamidase beta subunit-like C-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Tryptophan synthase beta chain-like PALP
Diacylglycerol glucosyltransferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Pyridoxamine 5'-phosphate oxidase putative
Penicillin-binding protein transpeptidase
TrbL/VirB6 plasmid conjugal transfer protein
Methionyl-tRNA synthetase anticodon-binding
Cytochrome C biogenesis protein transmembrane
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glutathionylspermidine synthase pre-ATP-grasp-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Ribose-phosphate pyrophosphokinase N-terminal
Involved in allosteric activation by GTP
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Formamidopyrimidine-DNA glycosylase catalytic
Mycothiol-dependent maleylpyruvate isomerase metal-binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Exonuclease VII large subunit C-terminal
Terminase large subunit-like endonuclease
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Cell wall-active antibiotics response LiaF-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
YbaK/aminoacyl-tRNA synthetase-associated
DNA replication/recombination mediator RecO N-terminal
Signal recognition particle SRP54 helical bundle
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Peptidase M43 pregnancy-associated plasma-A
Alpha-glycerophosphate oxidase C-terminal
Putative regulatory protein FmdB Zinc ribbon
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Acyltransferase MbtK/IucB-like conserved
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
N6 adenine-specific DNA methyltransferase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Schiff-base intermediate with D-ribose 5-phosphate
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
ABC-type glycine betaine transport system substrate-binding
Thiopeptide-type bacteriocin biosynthesis
DNA primase/polymerase bifunctional N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Small ribosomal subunit protein uS4 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL6 alpha-beta
Peptide methionine sulphoxide reductase MsrA
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Capsule polysaccharide biosynthesis protein
Myo-inositol-1-phosphate synthase GAPDH-like
Erythromycin biosynthesis protein CIII-like central
L,D-transpeptidase catalytic domain-containing protein
Threonine/serine exporter-like N-terminal
Glycosyltransferase subfamily 4-like N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Styrene monooxygenase StyA putative substrate binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Prokaryotic-type class I peptide chain release factors
Thiamine pyrophosphate enzyme TPP-binding
Cytochrome b/b6 N-terminal region profile
Membrane insertase YidC/Oxa/ALB C-terminal
Cell envelope-related transcriptional attenuator
Translation elongation factor P/YeiP central
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Alanyl-transfer RNA synthetases family profile
Alpha-D-phosphohexomutase alpha/beta/alpha
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Cytochrome bc1 complex cytochrome c subunit
Schiff-base intermediate with substrate; via pyruvic acid
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Leucine-binding protein domain-containing protein
Bacterial bifunctional deaminase-reductase C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycine cleavage T-protein C-terminal barrel
Peptidase M1 membrane alanine aminopeptidase
RNA polymerase sigma factor 70 region 4 type 2
Aminoacyl-transfer RNA synthetases class-II family profile
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Glycosyl transferase family 3 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Nicotinate phosphoribosyltransferase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
SUF system FeS cluster assembly SufBD N-terminal
PhoD-like phosphatase metallophosphatase
Could be important to modulate the pK values of the two catalytic cysteine residues
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Sporulation transcription regulator WhiA N-terminal
Phosphoribosylformylglycinamidine synthase linker
Peptidoglycan recognition protein family
NADH:ubiquinone oxidoreductase 30kDa subunit
Quercetin 2,3-dioxygenase C-terminal cupin
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Gamma-glutamylcyclotransferase AIG2-like
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
vWA-MoxR associated protein middle region 2
Pyruvate phosphate dikinase AMP/ATP-binding
N-acetylneuraminic acid synthase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
S-adenosyl-L-homocysteine hydrolase NAD binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Tat pathway signal sequence domain protein
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glycoside hydrolase family 31 N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
PknH-like extracellular domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Histidine-specific methyltransferase SAM-dependent
Large ribosomal subunit protein uL2 C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Reversibly protonated during proton transport
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Phosphatidic acid phosphatase type 2/haloperoxidase
Phosphoadenosine phosphosulphate reductase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Plays an important role in substrate specificity
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Large ribosomal subunit protein uL15/eL18
Pyrroline-5-carboxylate reductase catalytic N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Important for beta-aspartyl-AMP intermediate formation
Gram-positive cocci surface proteins LPxTG
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Cation-transporting P-type ATPase N-terminal
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Transcription regulator AsnC/Lrp ligand binding
Bacterial type II secretion system protein E
Cytochrome oxidase subunit II copper A binding
O-(5'-phospho-DNA)-tyrosine intermediate
CobB/CobQ-like glutamine amidotransferase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Heat-inducible transcription repressor HrcA C-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Essential for prephenate dehydratase activity
Polymerase/histidinol phosphatase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B domain-containing protein
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Anthranilate synthase component I N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
RNA 2-O ribose methyltransferase substrate binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Ribosomal RNA adenine methylase transferase N-terminal
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Fibronectin type-III domain-containing protein
ABC transporter substrate-binding protein PnrA-like
Putative glycogen debranching enzyme N-terminal
Pyruvate dehydrogenase E1 component middle
Phosphomannose isomerase type I catalytic
Molybdopterin cofactor biosynthesis C (MoaC)
Beta-hexosaminidase bacterial type N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Positions MEP for the nucleophilic attack
6-phosphogluconate dehydrogenase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
ATP synthase F1 complex delta/epsilon subunit N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Ionotropic glutamate receptor C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Inosine/uridine-preferring nucleoside hydrolase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Lactate utilization protein B C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Endoribonuclease L-PSP/chorismate mutase-like