Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Pseudouridine synthase I TruA alpha/beta
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Outer membrane protein beta-barrel domain-containing protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
DNA-directed RNA polymerase RpoA/D/Rpb3-type
TRAP C4-dicarboxylate transport system permease DctM subunit
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Bacterial type II secretion system protein E
Thymidylate synthase/dCMP hydroxymethylase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Survival protein SurE-like phosphatase/nucleotidase
Gamma-glutamylcyclotransferase AIG2-like
Pyruvate phosphate dikinase AMP/ATP-binding
Cytochrome b561 bacterial/Ni-hydrogenase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aminoacyl-transfer RNA synthetases class-II family profile
Flagellar assembly protein FliH/Type III secretion system HrpE
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Acyl-CoA dehydrogenase C-terminal bacterial-type
RND efflux pump membrane fusion protein barrel-sandwich
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Penicillin-binding protein transpeptidase
Quercetin 2,3-dioxygenase C-terminal cupin
TonB-dependent receptor-like beta-barrel
Outer membrane protein assembly factor BamA
Peptide methionine sulphoxide reductase MsrA
Prokaryotic-type class I peptide chain release factors
Alginate export domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Helix-hairpin-helix DNA-binding motif class 1
RND type efflux pump involved in aminoglycoside resistance
SUF system FeS cluster assembly SufBD N-terminal
HTH-type transcriptional repressor KstR2 C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Recombination protein RecR C4-type zinc finger
Gamma-butyrobetaine hydroxylase-like N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Electron transfer via tryptophanyl radical
TonB-dependent receptor plug domain-containing protein
Sodium symporter small subunit predicted
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Release factor glutamine methyltransferase N-terminal
Sugar fermentation stimulation protein C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Tryptophan synthase beta chain-like PALP
ATP synthase F1 complex delta/epsilon subunit N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Major facilitator superfamily (MFS) profile
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Proton acceptor; for glutaminase activity
Outer membrane lipoprotein-sorting protein
Polysaccharide biosynthesis protein C-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Outer-membrane lipoprotein carrier protein
Resolvase/invertase-type recombinase catalytic
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG middle
Glycosyl transferase family 3 N-terminal
Exonuclease VII large subunit C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Polysaccharide biosynthesis protein CapD-like
Glycoside hydrolase family 42 N-terminal
Glycoside hydrolase family 42 N-terminal domain-containing protein
Alpha-glycerophosphate oxidase C-terminal
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Translation elongation factor P/YeiP central
Type II secretion system protein GspI C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Cysteine sulfenic acid (-SOH) intermediate
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Important for interaction with partner proteins
Required for zinc-mediated homotetramerization and catalytic activity
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Interaction with polymerase core subunit RpoC
Interacts with tRNA; defines subfamily-specific binding signature
Alpha-D-phosphohexomutase alpha/beta/alpha
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Beta-lactamase hydrolase-like protein phosphatase-like
Chromosomal replication initiator DnaA C-terminal
Manganese/iron superoxide dismutase C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cob(I)alamin adenosyltransferase N-terminal
Thiol:disulfide interchange protein DsbD
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Important for substrate binding and specificity
TonB system biopolymer transport component
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Pyridoxamine 5'-phosphate oxidase putative
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
DNA-directed DNA polymerase family A palm
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Membrane dipeptidase (Peptidase family M19)
RNA 2-O ribose methyltransferase substrate binding
Membrane insertase YidC/Oxa/ALB C-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Urea ABC transporter substrate-binding protein
Transcription elongation factor GreA/GreB N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Large ribosomal subunit protein uL6 alpha-beta
Anti-bacteriophage protein A/HamA C-terminal
Polysaccharide chain length determinant N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Inosine/uridine-preferring nucleoside hydrolase
Secretin/TonB short N-terminal domain-containing protein
Peptidase M6-like domain-containing protein
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycoside-hydrolase family GH114 TIM-barrel
Flagellar motor switch protein FliN-like C-terminal
Erythronate-4-phosphate dehydrogenase dimerisation
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Small ribosomal subunit protein uS4 N-terminal
PhoD-like phosphatase metallophosphatase
Translation elongation factor EFTs/EF1B dimerisation
Gp5/Type VI secretion system Vgr protein OB-fold
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
NIF system FeS cluster assembly NifU C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL15/eL18
Gly-cisPro motif, important for rejection of L-amino acids
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Divergent polysaccharide deacetylase family protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Membrane fusion protein biotin-lipoyl like
Type I restriction enzyme R protein N-terminal
Lytic transglycosylase superhelical linker
Signal transduction histidine kinase internal region
Mannose-6-phosphate isomerase type II C-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Type III secretion system flagellar brake protein YcgR PilZN
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Glycosyltransferase subfamily 4-like N-terminal
Water stress and hypersensitive response
Chromosomal replication initiator protein DnaA
Large ribosomal subunit protein uL30-like ferredoxin-like fold
ATP-dependent DNA helicase RecG C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Alanyl-transfer RNA synthetases family profile
Phosphatidic acid phosphatase type 2/haloperoxidase
Inner membrane protein YgaP-like transmembrane
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Thrombospondin type 3 repeat-containing protein
Putative regulatory protein FmdB Zinc ribbon
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Endonuclease YhcR N-terminal domain-containing protein
ABC transporter substrate-binding protein PnrA-like
Type VI secretion system IcmF C-terminal
Bacterial virulence factor lipase N-terminal
Bacterial virulence factor lipase N-terminal domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Type I restriction modification DNA specificity
Dienelactone hydrolase domain-containing protein
Cation-transporting P-type ATPase N-terminal
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Glucosamine/galactosamine-6-phosphate isomerase
Anthranilate synthase component I N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
UDP N-acetylglucosamine O-acyltransferase C-terminal
Sodium/calcium exchanger membrane region
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Carbamoyl-phosphate synthase small subunit N-terminal
Sec translocon accessory complex subunit YajC
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Type II secretion system protein GspG C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Bacterial surface antigen (D15) domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Plays an important role in substrate specificity
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
DNA mismatch repair proteins mutS family
Outer membrane protein assembly factor BamB
Urease accessory protein UreH-like transmembrane
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-97)
Cell division protein FtsQ/DivIB C-terminal
Glycine cleavage T-protein C-terminal barrel
Polymerase/histidinol phosphatase N-terminal
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
Polypeptide-transport-associated ShlB-type
Transcription factor NikR nickel binding C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
N6 adenine-specific DNA methyltransferase N-terminal
Essential for prephenate dehydratase activity
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Large ribosomal subunit protein uL2 C-terminal
PilC beta-propeller domain-containing protein
S-adenosylmethionine-dependent methyltransferase
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
RNA methyltransferase SpoU/TrmH type C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Manganese/iron superoxide dismutase N-terminal
Solute-binding protein family 5 domain-containing protein
Bacterial Ig-like domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding