Carbamoyl-phosphate synthase small subunit N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Rap1a immunity protein domain-containing protein
Translocation and assembly module subunit TamA
Major facilitator superfamily (MFS) profile
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Resolvase/invertase-type recombinase catalytic
Seems to be a necessary countercharge to the potassium cations
Penicillin-binding protein transpeptidase
TonB-dependent receptor-like beta-barrel
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Tryptophan synthase beta chain-like PALP
ToxR activated gene A lipoprotein domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Important for interaction with partner proteins
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Large ribosomal subunit protein uL2 C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Poly-beta-hydroxybutyrate polymerase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Positions MEP for the nucleophilic attack
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Bacterial type II secretion system protein E
DNA polymerase III subunit delta C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Aminoacyl-transfer RNA synthetases class-II family profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Type 4 fimbrial biogenesis protein PilX N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Integrating conjugative element protein, family
DNA-directed DNA polymerase family A palm
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Flagellar hook-length control protein-like C-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Organic solvent tolerance-like N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Sulfatase-modifying factor enzyme domain-containing protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Gp5/Type VI secretion system Vgr protein OB-fold
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Shikimate dehydrogenase substrate binding N-terminal
N-end rule aminoacyl transferase C-terminal
Calcium/calmodulin-dependent protein kinase II association-domain
RND efflux pump membrane fusion protein barrel-sandwich
RNA polymerase sigma factor 70 region 4 type 2
S-adenosyl-L-homocysteine hydrolase NAD binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Plays an important role in substrate specificity
NADH:ubiquinone oxidoreductase 30kDa subunit
Inner membrane protein YgaP-like transmembrane
Leucine-binding protein domain-containing protein
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Chromosomal replication initiator DnaA C-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Cytochrome b561 bacterial/Ni-hydrogenase
Glucosamine/galactosamine-6-phosphate isomerase
Mannose-6-phosphate isomerase type II C-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
ABC-type glycine betaine transport system substrate-binding
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
RNA 2-O ribose methyltransferase substrate binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Phosphatidic acid phosphatase type 2/haloperoxidase
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Alpha-glycerophosphate oxidase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Phosphoadenosine phosphosulphate reductase
Required for dimer formation and molybdate binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Gfo/Idh/MocA-like oxidoreductase N-terminal
Putative ATP-dependent zinc protease domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Outer membrane protein assembly factor BamA
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Integral membrane protein YccS N-terminal
Glutamate synthase alpha subunit C-terminal
Membrane fusion protein biotin-lipoyl like
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Glycosyltransferase subfamily 4-like N-terminal
Superoxide dismutase copper/zinc binding
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 2
Lytic transglycosylase superhelical linker
PhoD-like phosphatase metallophosphatase
Glycine cleavage T-protein C-terminal barrel
ABC transporter substrate-binding protein PnrA-like
Flagellar motor switch protein FliN-like C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Prokaryotic-type class I peptide chain release factors
Bacteriophage tail tape measure C-terminal
Bacteriophage tail tape measure N-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
ABC transporter, periplasmic substrate-binding protein
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Pyruvate phosphate dikinase AMP/ATP-binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Interaction with polymerase core subunit RpoC
Periplasmic binding protein/LacI sugar binding
The binding site for the sugar molecule has not yet been established, but C-87 may be involved
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glutathionylspermidine synthase pre-ATP-grasp-like
Lysozyme inhibitor LprI N-terminal domain-containing protein
Sodium/calcium exchanger membrane region
Gly-cisPro motif, important for rejection of L-amino acids
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Cupin 2 conserved barrel domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Guanylate kinase/L-type calcium channel beta subunit
S-adenosylmethionine-dependent methyltransferase
Type II secretion system protein GspE N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesi
Nucleophile; cysteine thiosulfonate intermediate
Small ribosomal subunit protein uS4 N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
DNA topoisomerase I catalytic core eukaryotic-type
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA polymerase III delta subunit C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Type II secretion system protein GspC N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
L,D-transpeptidase catalytic domain-containing protein
Signal transduction histidine kinase internal region
Pyridoxamine 5'-phosphate oxidase putative
Peptidase S9 prolyl oligopeptidase catalytic
Type VI secretion system IcmF C-terminal
Heme-copper oxidase subunit III family profile
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Reversibly protonated during proton transport
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Electron transfer via tryptophanyl radical
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
O-(phosphoribosyl dephospho-coenzyme A)serine
Malonate/sodium symporter MadM subunit N-terminal
Glycosyl transferase family 3 N-terminal
Proton acceptor; for decarboxylase activity
Proton donor; for decarboxylase activity
Proton donor; for formyltransferase activity
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Release factor glutamine methyltransferase N-terminal
Fimbrial-type adhesion domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Important for substrate binding and specificity
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Cytochrome c-type biogenesis protein CcmF C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Mandelate racemase/muconate lactonizing enzyme C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Glycine zipper domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Pyruvate dehydrogenase E1 component middle
Important for autoinhibition of adenylyltransferase activity
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Essential for prephenate dehydratase activity
Bacteriophage N4 adsorption protein A C-terminal
Bacteriophage N4 adsorption protein A C-terminal domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Peptide methionine sulphoxide reductase MsrA
Endolytic peptidoglycan transglycosylase RlpA
Lytic murein transglycosylase D lipid attachment
Proline utilization A proline dehydrogenase N-terminal
Outer membrane lipoprotein carrier protein LolA
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
2-oxoacid:ferredoxin oxidoreductase, alpha subunit
Flagellar assembly protein FliH/Type III secretion system HrpE
Membrane insertase YidC/Oxa/ALB C-terminal
ssDNA thymidine ADP-ribosyltransferase DarT
Putative type VI secretion system Rhs element associated Vgr
Hypersensitivity response secretion-like HrpJ
Type III secretion system effector delivery regulator TyeA
Acyl-CoA dehydrogenase C-terminal bacterial-type
ABC-type transport auxiliary lipoprotein component
Type III secretion system flagellar brake protein YcgR PilZN
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Interacts with tRNA; defines subfamily-specific binding signature
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)
Outer-membrane lipoprotein carrier protein
Large ribosomal subunit protein uL15/eL18
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Inosine/uridine-preferring nucleoside hydrolase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase N-terminal
ABC-type transport auxiliary lipoprotein component domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Phosphoethanolamine transferase N-terminal
Nucleoside-binding outer membrane protein
Archaeal S-adenosylmethionine synthetase
Gfo/Idh/MocA-like oxidoreductase C-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Water stress and hypersensitive response
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
DNA replication/recombination mediator RecO N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Urease accessory protein UreH-like transmembrane
Adaptive response protein AidB N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA-binding transcriptional regulator CynR
Transposon Tn7 transposition protein TnsD C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Disulphide bond isomerase DsbC/G N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Lipoprotein SmpA/OmlA domain-containing protein
Nitrite/Sulfite reductase ferredoxin-like
Sugar fermentation stimulation protein C-terminal
Helix-hairpin-helix DNA-binding motif class 1
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Quercetin 2,3-dioxygenase C-terminal cupin
Antitoxin Xre/MbcA/ParS-like toxin-binding
Lipopolysaccharide export system protein LptA
Lipoprotein YgdI/YgdR-like SH3-like domain-containing protein
4'-phosphopantetheinyl transferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Arginine decarboxylase C-terminal helical