Type II secretion system protein GspC N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Cation-transporting P-type ATPase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Acetylserotonin O-methyltransferase dimerisation
Glycosyltransferase subfamily 4-like N-terminal
Major facilitator superfamily (MFS) profile
Type VI secretion system IcmF C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Prokaryotic-type class I peptide chain release factors
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Essential for prephenate dehydratase activity
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Outer membrane protein beta-barrel domain-containing protein
Bacterial type II secretion system protein E
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Tryptophan synthase beta chain-like PALP
Major facilitator superfamily associated
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Interaction with polymerase core subunit RpoC
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Bacterial EndoU nuclease domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
ATP synthase F1 complex delta/epsilon subunit N-terminal
Plays an important role in substrate specificity
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Alpha-D-phosphohexomutase alpha/beta/alpha
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Peptidase S9 prolyl oligopeptidase catalytic
O-(3'-phospho-DNA)-tyrosine intermediate
Calcium-dependent cell adhesion molecule N-terminal
Calcium-dependent cell adhesion molecule N-terminal domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Glycosyl transferase family 28 C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Na+/H+ antiporter MnhB subunit-related protein
Large ribosomal subunit protein uL2 C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Large ribosomal subunit protein uL15/eL18
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Type II secretion system protein GspG C-terminal
Prepilin type IV endopeptidase peptidase
peptide-methionine (R)-S-oxide reductase
Pseudouridine synthase I TruA alpha/beta
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Membrane insertase YidC/Oxa/ALB C-terminal
Resolvase/invertase-type recombinase catalytic
Survival protein SurE-like phosphatase/nucleotidase
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Lysozyme inhibitor LprI N-terminal domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Polysaccharide chain length determinant N-terminal
Phosphotransferase system enzyme I N-terminal
Outer membrane protein assembly factor BamA
Lysidine-tRNA(Ile) synthetase C-terminal
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Type II restriction enzyme and methyltransferase RM.Eco57I-like
DNA mismatch repair proteins mutS family
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Penicillin-binding protein transpeptidase
Quercetin 2,3-dioxygenase C-terminal cupin
Translation elongation factor P/YeiP central
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Small ribosomal subunit protein uS4 N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Water stress and hypersensitive response
DNA replication/recombination mediator RecO N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Pyruvate phosphate dikinase AMP/ATP-binding
Chromosomal replication initiator protein DnaA
N-acetylneuraminic acid synthase N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
ABC-type transport auxiliary lipoprotein component
Lytic transglycosylase superhelical linker
Mitochondrial apoptosis-inducing factor C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Putative Flp pilus-assembly TadG-like N-terminal
TonB-dependent receptor-like beta-barrel
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Anthranilate synthase component I N-terminal
PEP-CTERM sorting domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Helix-hairpin-helix DNA-binding motif class 1
Polymerase/histidinol phosphatase N-terminal
Glycine-zipper-containing OmpA-like membrane
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Alpha-L-glutamate ligase-related protein ATP-grasp
DNA polymerase III delta subunit C-terminal
Disulphide bond isomerase DsbC/G N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
PEP-CTERM protein-sorting domain-containing protein
DNA-directed DNA polymerase family A palm
Type I restriction enzyme R protein N-terminal
Peptidase M1 membrane alanine aminopeptidase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Flagellar motor switch protein FliN-like C-terminal
Outer membrane protein assembly factor BamD
Reversibly protonated during proton transport
6-phosphogluconate dehydrogenase C-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
RNA binding; important for wobble base 34 recognition
Activator of Hsp90 ATPase homologue 1-like C-terminal
Pyruvate dehydrogenase E1 component middle
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Putative regulatory protein FmdB Zinc ribbon
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
DNA polymerase III subunit delta C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Release factor glutamine methyltransferase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Flagellar hook-length control protein-like C-terminal
Glycosyl transferase family 3 N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Type 2A encapsulin shell protein SrpI-like
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Cation-transporting P-type ATPase C-terminal
Proline utilization A proline dehydrogenase N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Proton acceptor; for glutaminase activity
Ribulose bisphosphate carboxylase small subunit
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
N-end rule aminoacyl transferase C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
CNP1-like uncharacterized domain-containing protein
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Peptide methionine sulphoxide reductase MsrA
Regulator of nucleoside diphosphate kinase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
RNA 2-O ribose methyltransferase substrate binding
Acyl-CoA dehydrogenase C-terminal bacterial-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
PhoD-like phosphatase metallophosphatase
Coenzyme Q-binding protein COQ10 START domain-containing protein
Gp5/Type VI secretion system Vgr protein OB-fold
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Peptidoglycan recognition protein family
Positions MEP for the nucleophilic attack
Putative beta-lactamase-inhibitor-like PepSY-like
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Phage terminase large subunit N-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Gamma-butyrobetaine hydroxylase-like N-terminal
Formylmethanofuran dehydrogenase subunit E
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Thymidylate synthase/dCMP hydroxymethylase
Required for zinc-mediated homotetramerization and catalytic activity
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Bacteriophage tail tape measure N-terminal
Tc toxin complex TcA C-terminal TcB-binding
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Important for interaction with partner proteins
NAD(P) transhydrogenase alpha subunit C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Cysteine sulfenic acid (-SOH) intermediate
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
O-(5'-phospho-DNA)-tyrosine intermediate
Chromosomal replication initiator DnaA C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Signal recognition particle SRP54 helical bundle
Cytochrome P460 domain-containing protein
Phosphoadenosine phosphosulphate reductase
SUF system FeS cluster assembly SufBD N-terminal
Polypeptide-transport-associated ShlB-type
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal