AB hydrolase-1 domain-containing protein
Glycosyltransferase subfamily 4-like N-terminal
Major facilitator superfamily (MFS) profile
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Important for beta-aspartyl-AMP intermediate formation
Penicillin-binding protein transpeptidase
PHA accumulation regulator DNA-binding N-terminal
Peptide ABC transporter substrate-binding protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Right handed beta helix domain-containing protein
Outer membrane protein beta-barrel domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
TonB-dependent receptor-like beta-barrel
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
ABC transporter substrate-binding protein
Peptidase S9 prolyl oligopeptidase catalytic
Aminoacyl-transfer RNA synthetases class-II family profile
Molybdopterin cofactor biosynthesis C (MoaC)
Bacterial type II secretion system protein E
Type II secretion system protein GspE N-terminal
RNA polymerase sigma factor 70 region 4 type 2
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Translation elongation factor P/YeiP central
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Phosphate/phosphite/phosphonate ABC transporter substrate-binding protein
RND efflux pump membrane fusion protein barrel-sandwich
PhoD-like phosphatase metallophosphatase
Proton acceptor; for glutaminase activity
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Peptidase M64 N-terminal domain-containing protein
Interacts with tRNA; defines subfamily-specific binding signature
Peptidase M61 catalytic domain-containing protein
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Glycine cleavage T-protein C-terminal barrel
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
S-adenosylmethionine-dependent methyltransferase
Terminase large subunit gp17-like C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Exonuclease VII large subunit C-terminal
Peptidase metallopeptidase domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Outer membrane beta-barrel domain-containing protein
Blue (type 1) copper domain-containing protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
FAD-dependent oxidoreductase 2 FAD binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
SMODS-associated and fused to various effectors
UDP N-acetylglucosamine O-acyltransferase C-terminal
ABC-type uncharacterised transport system
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Type II secretion system protein GspG C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
IgGFc-binding protein N-terminal domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Fibronectin type-III domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Peptidase M1 membrane alanine aminopeptidase
S-adenosyl-L-homocysteine hydrolase NAD binding
General stress protein FMN-binding split barrel
Heat-inducible transcription repressor HrcA C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Peptidase M15C domain-containing protein
Threonine/serine exporter-like N-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Interaction with polymerase core subunit RpoC
Activator of Hsp90 ATPase homologue 1-like C-terminal
Pseudouridine synthase I TruA alpha/beta
Pyridine nucleotide-disulphide oxidoreductase dimerisation
3-beta hydroxysteroid dehydrogenase/isomerase
Putative Flp pilus-assembly TadG-like N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Ricin B lectin domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Gamma-butyrobetaine hydroxylase-like N-terminal
Prokaryotic-type class I peptide chain release factors
Alpha-D-phosphohexomutase alpha/beta/alpha
2-oxoacid dehydrogenase acyltransferase catalytic
Alginate export domain-containing protein
DNA-directed DNA polymerase family A palm
LamG-like jellyroll fold domain-containing protein
Inner membrane protein YgaP-like transmembrane
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Uncharacterized protein YfbK C-terminal domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Thymidylate synthase/dCMP hydroxymethylase
Abnormal spindle-like microcephaly-associated protein ASH
Transmembrane protein 131-like N-terminal
Signal recognition particle SRP54 helical bundle
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Biopterin-dependent aromatic amino acid hydroxylase family profile
Diiron non-heme beta-hydroxylase N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Phosphatidate phosphatase APP1 catalytic
Mandelate racemase/muconate lactonizing enzyme C-terminal
Plays an important role in substrate specificity
Poly (ADP-ribose) glycohydrolase (PARG) catalytic
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Microcin J25-processing protein McjB C-terminal
Microcin J25-processing protein McjB C-terminal domain-containing protein
SUF system FeS cluster assembly SufBD N-terminal
Prepilin type IV endopeptidase peptidase
Glucose/Sorbosone dehydrogenase domain-containing protein
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Carbamoyl-phosphate synthase small subunit N-terminal
L-seryl-tRNA selenium transferase N-terminal
Glycoside-hydrolase family GH114 TIM-barrel
Type I restriction enzyme R protein N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Polysaccharide chain length determinant N-terminal
Haem-binding uptake Tiki superfamily ChaN
Cytochrome c-type biogenesis protein CcmF C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Trigger factor ribosome-binding bacterial
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Peptidase M10 metallopeptidase domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Signal transduction histidine kinase internal region
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Bacterial virulence factor lipase N-terminal
Chromosomal replication initiator DnaA C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
EfeO-type cupredoxin-like domain-containing protein
Histidine-specific methyltransferase SAM-dependent
Glycosyl hydrolases family 45 active site
Cation-transporting P-type ATPase N-terminal
Outer membrane lipoprotein-sorting protein
Integral membrane protein YccS N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Putative oxidoreductase/dehydrogenase Rossmann-like
Putative auto-transporter adhesin head GIN
Type II secretion system protein GspC N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Cytochrome b561 bacterial/Ni-hydrogenase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Important for interaction with partner proteins
YbaK/aminoacyl-tRNA synthetase-associated
O-(3'-phospho-DNA)-tyrosine intermediate
Adventurous gliding motility protein CglE
Phosphotransferase system enzyme I N-terminal
Predicted DNA-binding protein ribbon-helix-helix
Polyketide synthase phosphopantetheine-binding
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Phosphoadenosine phosphosulphate reductase
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Ribosomal RNA small subunit methyltransferase E methyltransferase
Choloylglycine hydrolase/NAAA C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Peptidase M43 pregnancy-associated plasma-A
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Polymerase/histidinol phosphatase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Urease accessory protein UreH-like transmembrane
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
6-phosphogluconate dehydrogenase NADP-binding
Myo-inositol-1-phosphate synthase GAPDH-like
Reversibly protonated during proton transport
Formylmethanofuran dehydrogenase subunit E
Formylmethanofuran dehydrogenase subunit E domain-containing protein
RNA binding; important for wobble base 34 recognition
Winged helix-turn-helix domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
CobB/CobQ-like glutamine amidotransferase
PilC beta-propeller domain-containing protein
Dickkopf N-terminal cysteine-rich domain-containing protein
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Outer membrane lipoprotein BamD-like domain-containing protein
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Membrane insertase YidC/Oxa/ALB C-terminal
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Membrane fusion protein biotin-lipoyl like
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Spore coat protein U domain-containing protein
Anthranilate synthase component I N-terminal
Chitobiase/beta-hexosaminidases N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Bacterial Ig-like domain-containing protein
Beta-lactamase class A catalytic domain-containing protein
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Chalcone isomerase domain-containing protein
Peptidase MA-like domain-containing protein
Alpha-glycerophosphate oxidase C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Flagellar assembly protein FliH/Type III secretion system HrpE
Carbohydrate-binding domain-containing protein
Beta-propeller repeat-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
RNA 3'-terminal phosphate cyclase insert
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Alpha-2-macroglobulin domain-containing protein
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Next to BRCA1 central domain-containing protein
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
2,4-diaminopentanoate dehydrogenase C-terminal
DNA replication/recombination mediator RecO N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Zinc-regulated TonB-dependent outer membrane receptor
Bacterial bifunctional deaminase-reductase C-terminal
Styrene monooxygenase StyA putative substrate binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Schiff-base intermediate with substrate; via pyruvic acid
GlsB/YeaQ/YmgE family stress response membrane protein
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
SGNH hydrolase-type esterase domain-containing protein
Flagellar motor switch protein FliN-like C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Alanyl-transfer RNA synthetases family profile
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Na+/H+ antiporter MnhB subunit-related protein
Helix-hairpin-helix DNA-binding motif class 1
N-end rule aminoacyl transferase C-terminal
Large ribosomal subunit protein uL2 C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Outer membrane lipoprotein carrier protein LolA
Peptide methionine sulphoxide reductase MsrA
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Glycosyl transferase family 3 N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Type VI secretion system IcmF C-terminal
Type VI secretion system IcmF C-terminal domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pili assembly chaperone N-terminal domain-containing protein
AraC-type arabinose-binding/dimerisation
Cytochrome c-552/4 domain-containing protein
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Essential for prephenate dehydratase activity
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Menaquinone biosynthesis protein MenD middle
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Superoxide dismutase copper/zinc binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Adaptive response protein AidB N-terminal
Release factor glutamine methyltransferase N-terminal
Peptidase M17 leucyl aminopeptidase N-terminal
Anaphase-promoting complex subunit 4-like WD40
Cytochrome c7-like domain-containing protein
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Probable endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Neutral/alkaline non-lysosomal ceramidase C-terminal
Neutral/alkaline non-lysosomal ceramidase N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Could be important to modulate the pK values of the two catalytic cysteine residues
Acetylserotonin O-methyltransferase dimerisation
6-phosphogluconate dehydrogenase C-terminal
Cytochrome oxidase subunit II copper A binding
Water stress and hypersensitive response
Water stress and hypersensitive response domain-containing protein
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
RNA 2-O ribose methyltransferase substrate binding
Arginine decarboxylase C-terminal helical
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Putative peptidoglycan binding domain-containing protein
Peptidase M12A domain-containing protein
Heme-copper oxidase subunit III family profile
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Regulator of nucleoside diphosphate kinase N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Solute-binding protein family 3/N-terminal