Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Flagella basal body P-ring formation protein FlgA
Tryptophan synthase beta chain-like PALP
TonB-dependent receptor-like beta-barrel
Electron transfer flavoprotein alpha/beta-subunit N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Polymerase/histidinol phosphatase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Tripartite-type tricarboxylate transporter, receptor component TctC
Inosine/uridine-preferring nucleoside hydrolase
Flagellar motor switch protein FliN-like C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Restriction system protein Mrr-like N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Involved in ionization of N3 of dUMP, leading to its activation
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Glucose-methanol-choline oxidoreductase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Glycine cleavage T-protein C-terminal barrel
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
ABC-type glycine betaine transport system substrate-binding
Polysaccharide chain length determinant N-terminal
Prokaryotic-type class I peptide chain release factors
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-98)
Beta-lactamase hydrolase-like protein phosphatase-like
Required for zinc-mediated homotetramerization and catalytic activity
3-hydroxyacyl-CoA dehydrogenase C-terminal
RNA 2-O ribose methyltransferase substrate binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Proline utilization A proline dehydrogenase N-terminal
Major facilitator superfamily (MFS) profile
Magnesium transporter MgtE intracellular
Alpha-D-phosphohexomutase alpha/beta/alpha
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Cob(I)alamin adenosyltransferase N-terminal
6-phosphogluconate dehydrogenase C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Twin-arginine translocation pathway signal
Helix-hairpin-helix DNA-binding motif class 1
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Bacterial type II secretion system protein E
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
RNA binding; important for wobble base 34 recognition
Terminase large subunit-like endonuclease
Membrane fusion protein biotin-lipoyl like
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Large ribosomal subunit protein uL15/eL18
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
TRAP transporter solute receptor, TAXI family
Type II secretion system protein GspG C-terminal
Penicillin-binding protein transpeptidase
Chromosomal replication initiator DnaA C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Cysteine sulfenic acid (-SOH) intermediate
TRAP C4-dicarboxylate transport system permease DctM subunit
Heme-copper oxidase subunit III family profile
Cobaltochelatase subunit CobS N-terminal
Cytochrome C biogenesis protein transmembrane
Glycosyltransferase subfamily 4-like N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyrroline-5-carboxylate reductase catalytic N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Molybdopterin cofactor biosynthesis C (MoaC)
S-adenosyl-L-homocysteine hydrolase NAD binding
Inner membrane protein YgaP-like transmembrane
DNA-directed DNA polymerase family A palm
Sugar fermentation stimulation protein C-terminal
Reversibly protonated during proton transport
Flagellar hook-length control protein-like C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Transcription regulator AsnC/Lrp ligand binding
RNA polymerase sigma factor 70 region 4 type 2
Flagellar assembly protein FliH/Type III secretion system HrpE
Alanyl-transfer RNA synthetases family profile
Alpha-L-rhamnosidase six-hairpin glycosidase
Putative glycogen debranching enzyme N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
N-sulphoglucosamine sulphohydrolase C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Plays an important role in substrate specificity
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
YbaK/aminoacyl-tRNA synthetase-associated
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Glycosyl transferase family 3 N-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
NIF system FeS cluster assembly NifU N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Sodium symporter small subunit predicted
Acyl-CoA dehydrogenase/oxidase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Important for interaction with partner proteins
Large ribosomal subunit protein uL2 C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
O-(5'-phospho-DNA)-tyrosine intermediate
Acyl-CoA dehydrogenase/oxidase C-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Haem-binding uptake Tiki superfamily ChaN
Pyridoxamine 5'-phosphate oxidase putative
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Anti-bacteriophage protein A/HamA C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Acetylserotonin O-methyltransferase dimerisation
Alpha-glycerophosphate oxidase C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Prepilin type IV endopeptidase peptidase
ABC transporter substrate-binding protein PnrA-like
Oxidoreductase molybdopterin-binding domain-containing protein
3-hydroxyacyl-CoA dehydrogenase NAD binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Sodium/calcium exchanger membrane region
Membrane insertase YidC/Oxa/ALB C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
L,D-transpeptidase catalytic domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Acetyl-CoA dehydrogenase-like C-terminal
TtsA-like Glycoside hydrolase family 108
Invasion protein IalB, involved in pathogenesis
Proton acceptor; for glutaminase activity
Peptide methionine sulphoxide reductase MsrA
S-adenosylmethionine-dependent methyltransferase
Cytochrome b561 bacterial/Ni-hydrogenase
Small ribosomal subunit protein uS4 N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
NADH:ubiquinone oxidoreductase 30kDa subunit
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Plasmid replication protein C C-terminal
Plasmid replication protein C N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Cytochrome c oxidase subunit IV bacterial aa3 type
General stress protein FMN-binding split barrel
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Interaction with polymerase core subunit RpoC
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Cation-transporting P-type ATPase N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Polysaccharide biosynthesis protein CapD-like
Peptidase C39-like domain-containing protein
Cytochrome c-type biogenesis protein CcmF C-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Resolvase/invertase-type recombinase catalytic
Peptide methionine sulfoxide reductase MsrA
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
DnaJ homologue subfamily C member 28 conserved
Anthranilate synthase component I N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Type II secretion system protein TadB-like N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
ABC-type transport auxiliary lipoprotein component
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Ribose-phosphate pyrophosphokinase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Saccharopine dehydrogenase-like C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Type II secretion system protein GspC N-terminal
Cytochrome c-552/4 domain-containing protein
N-end rule aminoacyl transferase C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
PHA accumulation regulator DNA-binding N-terminal
Putative acyltransferase ACT14924-like acyltransferase
Tetracyclin repressor-like C-terminal group 31
Large ribosomal subunit protein uL6 alpha-beta
SUF system FeS cluster assembly SufBD N-terminal
Pseudouridine synthase I TruA alpha/beta
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Phosphoribosylformylglycinamidine synthase linker
Pyrroline-5-carboxylate reductase dimerisation
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Ribulose bisphosphate carboxylase small subunit
Moybdenum cofactor oxidoreductase dimerisation
Exonuclease VII large subunit C-terminal
Methionyl-tRNA synthetase anticodon-binding
O-(3'-phospho-DNA)-tyrosine intermediate
Probable periplasmic serine endoprotease DegP-like
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Organic solvent tolerance-like N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
tRNA pseudouridylate synthase B C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Heat-inducible transcription repressor HrcA C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Histidine phosphotransferase ChpT C-terminal
Translation elongation factor P/YeiP central
Survival protein SurE-like phosphatase/nucleotidase