Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Outer-membrane lipoprotein Wza C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
TonB-dependent receptor-like beta-barrel
Peptidase C-terminal archaeal/bacterial domain-containing protein
Plays an important role in substrate specificity
PPIase cyclophilin-type domain-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
RNA 2-O ribose methyltransferase substrate binding
Cupin 2 conserved barrel domain-containing protein
4Fe-4S ferredoxin-type domain-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
S-adenosyl-L-homocysteine hydrolase NAD binding
Xaa-Pro dipeptidyl-peptidase-like domain-containing protein
Penicillin-binding protein transpeptidase
Beta-lactamase hydrolase-like protein phosphatase-like
RNA binding; important for wobble base 34 recognition
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Important for substrate binding and specificity
Type II secretion system protein GspG C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Membrane insertase YidC/Oxa/ALB C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
PhoD-like phosphatase metallophosphatase
Lysidine-tRNA(Ile) synthetase C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Major facilitator superfamily (MFS) profile
Proline utilization A proline dehydrogenase N-terminal
Bacterial type II secretion system protein E
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Molybdopterin cofactor biosynthesis C (MoaC)
Sulfatase-modifying factor enzyme domain-containing protein
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Type II secretion system protein GspI C-terminal
Methylamine/Aralkylamine dehydrogenase light chain C-terminal
Tryptophylquinone 6'-substrate hemiaminal intermediate
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glycosyltransferase subfamily 4-like N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
SUF system FeS cluster assembly SufBD N-terminal
Plays an important role in discriminating NADH against NADPH
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Tryptophan synthase beta chain-like PALP
DNA replication/recombination mediator RecO N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Translation elongation factor P/YeiP central
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Outer membrane protein assembly factor BamA
RND efflux pump membrane fusion protein barrel-sandwich
Na+/H+ antiporter MnhB subunit-related protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Cytochrome oxidase subunit II copper A binding
TRAP C4-dicarboxylate transport system permease DctM subunit
Putative adhesin domain-containing protein
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
RNA polymerase sigma factor 70 region 4 type 2
Mannose-6-phosphate isomerase type II C-terminal
Transglycosylase SLT domain-containing protein
Glucose/Sorbosone dehydrogenase domain-containing protein
NIF system FeS cluster assembly NifU C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-105)
Chromosomal replication initiator DnaA C-terminal
Release factor glutamine methyltransferase N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Heme-copper oxidase subunit III family profile
ABC-type uncharacterised transport system
Lytic transglycosylase superhelical linker
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Reversibly protonated during proton transport
Urease accessory protein UreH-like transmembrane
Acyl-CoA dehydrogenase C-terminal bacterial-type
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Membrane fusion protein biotin-lipoyl like
Aconitase A/isopropylmalate dehydratase small subunit swivel
Gly-cisPro motif, important for rejection of L-amino acids
Flagellar basal-body/hook protein C-terminal
Sodium/calcium exchanger membrane region
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Proton acceptor; for glutaminase activity
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Pyruvate phosphate dikinase AMP/ATP-binding
Copper type II ascorbate-dependent monooxygenase C-terminal
Copper type II ascorbate-dependent monooxygenase C-terminal domain-containing protein
TonB system biopolymer transport component
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Polymerase/histidinol phosphatase N-terminal
DNA-directed DNA polymerase family A palm
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Peptide methionine sulphoxide reductase MsrA
Nitrite/Sulfite reductase ferredoxin-like
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Flagellar assembly protein FliH/Type III secretion system HrpE
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glyoxalase/fosfomycin resistance/dioxygenase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Fumarylacetoacetase-like C-terminal domain-containing protein
Lipocalin-like domain-containing protein
Cytochrome oxidase subunit II transmembrane region profile
Glycosyl transferase family 3 N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
TonB-dependent hemoglobin/transferrin/lactoferrin family receptor
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Pseudouridine synthase I TruA alpha/beta
Saccharopine dehydrogenase-like C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Cytochrome b561 bacterial/Ni-hydrogenase
O-(5'-phospho-DNA)-tyrosine intermediate
TonB-dependent receptor plug domain-containing protein
Disulphide bond isomerase DsbC/G N-terminal
Outer membrane protein beta-barrel domain-containing protein
Replication-associated protein G2P C-terminal
Replication-associated protein G2P N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Flagellar motor switch protein FliN-like C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Polysaccharide biosynthesis protein CapD-like
Required for dimer formation and molybdate binding
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Essential for prephenate dehydratase activity
ABC-type transport auxiliary lipoprotein component
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
HicB-like antitoxin of toxin-antitoxin system
Helix-hairpin-helix DNA-binding motif class 1
Organic solvent tolerance-like N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Endolytic peptidoglycan transglycosylase RlpA
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Shikimate dehydrogenase substrate binding N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Interaction with polymerase core subunit RpoC
Restriction endonuclease type II EcoRII C-terminal
Cytochrome P460 domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Flagellar basal body rod protein N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Haem-binding uptake Tiki superfamily ChaN
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Interacts with tRNA; defines subfamily-specific binding signature
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Polysaccharide chain length determinant N-terminal
Anthranilate synthase component I N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Prokaryotic-type class I peptide chain release factors
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Ribose-phosphate pyrophosphokinase N-terminal
DNA polymerase III subunit delta C-terminal
Flagellar hook-length control protein-like C-terminal
Resolvase/invertase-type recombinase catalytic
L-seryl-tRNA selenium transferase N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Amidohydrolase-related domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Translocation and assembly module subunit TamA
UDP N-acetylglucosamine O-acyltransferase C-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Aminotransferase class V domain-containing protein
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycine cleavage T-protein C-terminal barrel
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Exonuclease VII large subunit C-terminal
Large ribosomal subunit protein uL2 C-terminal
Sodium symporter small subunit predicted
Small ribosomal subunit protein uS4 N-terminal
Important for interaction with partner proteins
Gamma-glutamylcyclotransferase AIG2-like
Cytochrome c-type biogenesis protein CcmF C-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
High potential iron-sulfur proteins family profile
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Thymidylate synthase/dCMP hydroxymethylase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Arginine decarboxylase C-terminal helical
Large ribosomal subunit protein uL15/eL18