LamG-like jellyroll fold domain-containing protein
Solute-binding protein family 3/N-terminal
Glycosyltransferase subfamily 4-like N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Acyl-CoA dehydrogenase/oxidase C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DnaJ homologue subfamily C member 28 conserved
RNA polymerase sigma factor 70 region 4 type 2
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Plays an important role in substrate specificity
Penicillin-binding protein transpeptidase
FAD-dependent oxidoreductase 2 FAD binding
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Fibronectin type-III domain-containing protein
Tryptophan synthase beta chain-like PALP
Pyrimidine nucleoside phosphorylase C-terminal
Important for autoinhibition of adenylyltransferase activity
Interaction with polymerase core subunit RpoC
Putative adhesin domain-containing protein
Cytochrome b/b6 N-terminal region profile
Electron transfer via tryptophanyl radical
Acyl-CoA dehydrogenase/oxidase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cell wall anchor domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Prokaryotic-type class I peptide chain release factors
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
ABC-type glycine betaine transport system substrate-binding
DNA primase/polymerase bifunctional N-terminal
FtsX extracellular domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Major facilitator superfamily (MFS) profile
Alpha-D-phosphohexomutase alpha/beta/alpha
Glycoside-hydrolase family GH114 TIM-barrel
Endonuclease/exonuclease/phosphatase domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Heme-copper oxidase subunit III family profile
AMP-activated protein kinase glycogen-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Shikimate dehydrogenase substrate binding N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Phosphoadenosine phosphosulphate reductase
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Putative Flp pilus-assembly TadG-like N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Mannose-6-phosphate isomerase type II C-terminal
Alpha-L-arabinofuranosidase B arabinose-binding
Actinobacteria/chloroflexi VLRF1 release factor
Ricin B lectin domain-containing protein
Trigger factor ribosome-binding bacterial
PhoD-like phosphatase metallophosphatase
Glutathionylspermidine synthase pre-ATP-grasp-like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Bacterial type II secretion system protein E
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-127)
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Alpha-1,6-glucosidases pullulanase-type C-terminal
Glycoside hydrolase family 13 N-terminal
Pullulanase carbohydrate-binding module 41
Polymerase/histidinol phosphatase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Gram-positive cocci surface proteins LPxTG
Gram-positive cocci surface proteins LPxTG domain-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Peptide methionine sulphoxide reductase MsrA
Anthranilate synthase component I N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Myo-inositol-1-phosphate synthase GAPDH-like
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Schiff-base intermediate with substrate; via topaquinone
Gamma-glutamylcyclotransferase AIG2-like
Transcription regulator AsnC/Lrp ligand binding
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Alpha-glycerophosphate oxidase C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Mandelate racemase/muconate lactonizing enzyme C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
ATP synthase F1 complex delta/epsilon subunit N-terminal
Cell envelope-related transcriptional attenuator
Membrane insertase YidC/Oxa/ALB C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Beta-hexosaminidase bacterial type N-terminal
Flagellar hook-length control protein-like C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Glycoside hydrolase family 31 N-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Thiopeptide-type bacteriocin biosynthesis
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
SUF system FeS cluster assembly SufBD N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Translation elongation factor P/YeiP central
Lactate utilization protein B C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Peptidase M1 membrane alanine aminopeptidase
Transcriptional regulator LacI/GalR-like sensor
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Pyrroline-5-carboxylate reductase dimerisation
6-phosphogluconate dehydrogenase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Reversibly protonated during proton transport
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Activator of Hsp90 ATPase homologue 1-like C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
RND efflux pump membrane fusion protein barrel-sandwich
Cytochrome C biogenesis protein transmembrane
Phosphatidic acid phosphatase type 2/haloperoxidase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
3-beta hydroxysteroid dehydrogenase/isomerase
Saccharopine dehydrogenase-like C-terminal
Histidine-specific methyltransferase SAM-dependent
Heat-inducible transcription repressor HrcA C-terminal
Large ribosomal subunit protein uL15/eL18
Survival protein SurE-like phosphatase/nucleotidase
Glycoside hydrolase family 42 N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Pseudouridine synthase I TruA alpha/beta
Pectate lyase superfamily protein domain-containing protein
L-seryl-tRNA selenium transferase N-terminal
Glyoxalase/fosfomycin resistance/dioxygenase
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Glycosyltransferase family 28 N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Sporulation transcription regulator WhiA N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
MmyB-like transcription regulator ligand binding
Small ribosomal subunit protein uS4 N-terminal
Putative regulatory protein FmdB Zinc ribbon
Glucosamine/galactosamine-6-phosphate isomerase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Proton acceptor; for glutaminase activity
Beta-glucuronidase C-terminal domain-containing protein
DNA replication/recombination mediator RecO N-terminal
AB hydrolase-1 domain-containing protein
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Phosphotransferase system EIIB component type 2/3
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Inosine/uridine-preferring nucleoside hydrolase
Prepilin type IV endopeptidase peptidase
Essential for prephenate dehydratase activity
Important for substrate specificity; cannot use PPi as phosphoryl donor
Tat pathway signal sequence domain protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
YbaK/aminoacyl-tRNA synthetase-associated
NADH-ubiquinone oxidoreductase 51kDa subunit FMN-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Ionotropic glutamate receptor C-terminal
Sodium/calcium exchanger membrane region
Putative oxidoreductase/dehydrogenase Rossmann-like
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Formamidopyrimidine-DNA glycosylase catalytic
Positions MEP for the nucleophilic attack
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glycosyl transferase family 3 N-terminal
Chromosomal replication initiator DnaA C-terminal
Peptidoglycan recognition protein family
RlpA-like protein double-psi beta-barrel
Vanillate O-demethylase oxygenase-like C-terminal catalytic
Exonuclease VII large subunit C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Helix-hairpin-helix DNA-binding motif class 1
Ribose-phosphate pyrophosphokinase N-terminal
PknH-like extracellular domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)
Thymidylate synthase/dCMP hydroxymethylase
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
Carboxypeptidase regulatory-like domain-containing protein
Concanavalin A-like lectin/glucanase superfamily protein
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
L,D-transpeptidase catalytic domain-containing protein
Cell wall-active antibiotics response LiaF-like C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Peptidase S9 prolyl oligopeptidase catalytic
Na+/H+ antiporter MnhB subunit-related protein
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Moybdenum cofactor oxidoreductase dimerisation
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
N,N-dimethylformamidase beta subunit-like C-terminal
Glycoamylase-like domain-containing protein
Glycosyl transferase family 28 C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Putative glycogen debranching enzyme N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Pyruvate phosphate dikinase AMP/ATP-binding
Septum formation-related domain-containing protein
LPXTG-motif cell wall anchor domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Flagellar motor switch protein FliN-like C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Restriction system protein Mrr-like N-terminal
N-terminal domain of peptidoglycan hydrolase CwlO-containing protein
Alanyl-transfer RNA synthetases family profile
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
DNA-directed DNA polymerase family A palm
Could play a key role in the communication between the regulatory and the substrate sites
Right handed beta helix domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
TRAP transporter solute receptor TAXI family protein