Tripartite tricarboxylate transporter substrate binding protein
Large ribosomal subunit protein uL15/eL18
Flagellar hook-length control protein-like C-terminal
Major facilitator superfamily (MFS) profile
Phosphoribosylformylglycinamidine synthase linker
RNA polymerase sigma factor 70 region 4 type 2
Helix-hairpin-helix DNA-binding motif class 1
Aminoacyl-transfer RNA synthetases class-II family profile
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Glycosyltransferase subfamily 4-like N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Chromosomal replication initiator protein DnaA
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Flagellar motor switch protein FliN-like C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Nitroreductase domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Tryptophan synthase beta chain-like PALP
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Transposase IS116/IS110/IS902 C-terminal
RNA polymerase sigma factor 70 region 1.1
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyruvate phosphate dikinase AMP/ATP-binding
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Translation elongation factor P/YeiP central
S-adenosyl-L-homocysteine hydrolase NAD binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Solute-binding protein family 3/N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
NAD(P) transhydrogenase alpha subunit C-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Alpha-glycerophosphate oxidase C-terminal
Glycosyltransferase RgtA/B/C/D-like domain-containing protein
Cytochrome c-type biogenesis protein CcmF C-terminal
NIF system FeS cluster assembly NifU C-terminal
Outer membrane protein beta-barrel domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Cytochrome C biogenesis protein transmembrane
Membrane fusion protein biotin-lipoyl like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Mannose-6-phosphate isomerase type II C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
Soluble ligand binding domain-containing protein
Phenol hydroxylase C-terminal dimerisation
TRAP C4-dicarboxylate transport system permease DctM subunit
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
EfeO-type cupredoxin-like domain-containing protein
TonB-dependent receptor-like beta-barrel
DNA topoisomerase I catalytic core eukaryotic-type
Cytochrome oxidase subunit II copper A binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Prokaryotic-type class I peptide chain release factors
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 3
Heme-copper oxidase subunit III family profile
Essential for prephenate dehydratase activity
Polymerase/histidinol phosphatase N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-90)
Organic solvent tolerance-like N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Periplasmic nitrate reductase, electron transfer subunit
Small ribosomal subunit protein uS4 N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Penicillin-binding protein transpeptidase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Signal transduction histidine kinase HWE region
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
N-acetylmuramoyl-L-alanine amidase domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Prepilin type IV endopeptidase peptidase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Invasion associated locus B family protein
Magnesium-protoporphyrin IX methyltransferase C-terminal
SGNH hydrolase-type esterase domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Outer membrane protein assembly factor BamA
Hyphally-regulated cell wall protein N-terminal
Type IV secretion system coupling protein TraD DNA-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
O-(3'-phospho-DNA)-tyrosine intermediate
Bacterial type II secretion system protein E
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
RNA 2-O ribose methyltransferase substrate binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Activator of Hsp90 ATPase homologue 1-like C-terminal
Type I phosphodiesterase/nucleotide pyrophosphatase
Putative Flp pilus-assembly TadG-like N-terminal
Acetylserotonin O-methyltransferase dimerisation
Polysaccharide biosynthesis protein C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Amidohydrolase-related domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Glycine cleavage T-protein C-terminal barrel
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Glycosyl transferase family 3 N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
3-keto-disaccharide hydrolase domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
FAD-dependent oxidoreductase 2 FAD binding
Shikimate dehydrogenase substrate binding N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Gfo/Idh/MocA-like oxidoreductase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Bacterial bifunctional deaminase-reductase C-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
L,D-transpeptidase catalytic domain-containing protein
CDP-alcohol phosphatidyltransferase C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Leucine-binding protein domain-containing protein
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Sigma 54 modulation/S30EA ribosomal protein C-terminal
SUF system FeS cluster assembly SufBD N-terminal
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase-like C-terminal
Quinoprotein dehydrogenase-associated SoxYZ-like carrier
Dienelactone hydrolase domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Contractile injection system tube protein N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
6-phosphogluconate dehydrogenase C-terminal
RlpA-like protein double-psi beta-barrel
Siroheme decarboxylase AsnC-like ligand binding
ABC transporter substrate-binding protein PnrA-like
Phosphate starvation-inducible protein PsiF
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Cysteine sulfenic acid (-SOH) intermediate
Peptidase S9 prolyl oligopeptidase catalytic
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cytochrome c oxidase subunit IV bacterial aa3 type
4'-phosphopantetheinyl transferase N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Pyridoxamine 5'-phosphate oxidase putative
PhoD-like phosphatase metallophosphatase
Nitrite/Sulfite reductase ferredoxin-like
Exonuclease VII large subunit C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
AB hydrolase-1 domain-containing protein
Polysaccharide biosynthesis protein CapD-like
Peptidase C14 caspase domain-containing protein
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Saccharopine dehydrogenase-like C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Lysozyme inhibitor LprI N-terminal domain-containing protein
Adaptive response protein AidB N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Caspase family p20 domain-containing protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Putative regulatory protein FmdB Zinc ribbon
YVTN family beta-propeller repeat protein
Type I restriction modification DNA specificity
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Peptide methionine sulphoxide reductase MsrA
Alpha-D-phosphohexomutase alpha/beta/alpha
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
O-(5'-phospho-DNA)-tyrosine intermediate
Cation-transporting P-type ATPase N-terminal
Photosynthetic reaction centre H subunit N-terminal
DNA polymerase III beta sliding clamp N-terminal
Probable periplasmic serine endoprotease DegP-like
Type II secretion system protein GspG C-terminal
Release factor glutamine methyltransferase N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Ribulose bisphosphate carboxylase small subunit
Tc toxin complex TcA C-terminal TcB-binding
Organic solvent tolerance-like N-terminal domain-containing protein
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Putative glycogen debranching enzyme N-terminal
Interaction with polymerase core subunit RpoC
NADH:ubiquinone oxidoreductase chain 4 N-terminal
RNA binding; important for wobble base 34 recognition
Polysaccharide chain length determinant N-terminal
Important for interaction with partner proteins
Could play a key role in the communication between the regulatory and the substrate sites
NADH-rubredoxin oxidoreductase C-terminal
Thymidylate synthase/dCMP hydroxymethylase
Glucose/Sorbosone dehydrogenase domain-containing protein
Transcription regulator AsnC/Lrp ligand binding
ABC transporter substrate-binding protein
Gamma-glutamylcyclotransferase AIG2-like
TonB-dependent receptor plug domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Alginate export domain-containing protein
N-end rule aminoacyl transferase C-terminal
Aldehyde oxidase/xanthine dehydrogenase second molybdopterin binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
ABC-type transport auxiliary lipoprotein component
PHA accumulation regulator DNA-binding N-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Solute-binding protein family 5 domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
Glycine zipper domain-containing protein
Peptidoglycan binding-like domain-containing protein
AraC-type arabinose-binding/dimerisation
Could be important to modulate the pK values of the two catalytic cysteine residues
Required for zinc-mediated homotetramerization and catalytic activity
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Pilus formation protein N-terminal domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Moves into active site upon enzyme activation, plays a role in electron transfer
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Styrene monooxygenase StyA putative substrate binding
Jacalin-type lectin domain-containing protein
Inner membrane protein YgaP-like transmembrane
Septum formation inhibitor MinC C-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
N6 adenine-specific DNA methyltransferase N-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Ribose-phosphate pyrophosphokinase N-terminal
DNA primase/polymerase bifunctional N-terminal
Peptide methionine sulfoxide reductase MsrA
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Ionotropic glutamate receptor C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Nitrogenase molybdenum-iron protein beta chain N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Pseudouridine synthase I TruA alpha/beta
HupH hydrogenase expression protein C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Histidine phosphotransferase ChpT C-terminal
Serine aminopeptidase S33 domain-containing protein
Endoribonuclease L-PSP/chorismate mutase-like
Large ribosomal subunit protein uL6 alpha-beta
Methyl-accepting transducer domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Transcription factor NikR nickel binding C-terminal
Sodium/calcium exchanger membrane region
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Involved in tetramerization or stability of the tetramer
Acyltransferase MbtK/IucB-like conserved
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Thiol:disulfide interchange protein DsbD N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Cytochrome c-552/DMSO reductase-like haem-binding
Autotransporter domain-containing protein
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Histidine-specific methyltransferase SAM-dependent
Survival protein SurE-like phosphatase/nucleotidase
Bacterial transcription activator effector binding
Bacterial transcription activator effector binding domain-containing protein
Insecticide toxin TcdB middle/C-terminal
Insecticide toxin TcdB middle/N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Transglycosylase SLT domain-containing protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Reversibly protonated during proton transport
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
Moybdenum cofactor oxidoreductase dimerisation
Carbamoyl-phosphate synthase small subunit N-terminal
DNA replication/recombination mediator RecO N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Anthranilate synthase component I N-terminal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Heat-inducible transcription repressor HrcA C-terminal
Protein involved in meta-pathway of phenol degradation
Cytochrome oxidase subunit II transmembrane region profile
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
General stress protein FMN-binding split barrel
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Proton acceptor; for glutaminase activity
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Quercetin 2,3-dioxygenase C-terminal cupin
Transglutaminase-like cysteine proteinase BTLCP
Phosphotransferase system enzyme I N-terminal
AFL C-terminal domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Plays an important role in substrate specificity
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase