Resolvase/invertase-type recombinase catalytic
DNA-directed DNA polymerase family A palm
Pyrimidine nucleoside phosphorylase C-terminal
Solute-binding protein family 3/N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Major facilitator superfamily (MFS) profile
4'-phosphopantetheinyl transferase N-terminal
Cytochrome C biogenesis protein transmembrane
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Polymerase/histidinol phosphatase N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Membrane insertase YidC/Oxa/ALB C-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Important for substrate specificity; cannot use PPi as phosphoryl donor
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Chromosomal replication initiator DnaA C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
ATP-dependent DNA helicase RecG C-terminal
Plays an important role in substrate specificity
Phosphomannose isomerase type I catalytic
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Peptidoglycan recognition protein family
Electron transfer flavoprotein alpha/beta-subunit N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
RNA 2-O ribose methyltransferase substrate binding
Alanyl-transfer RNA synthetases family profile
FAD-dependent oxidoreductase 2 FAD binding
Pyruvate dehydrogenase E1 component middle
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Ribosomal RNA adenine methylase transferase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Tryptophan synthase beta chain-like PALP
Exonuclease VII large subunit C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Carbohydrate-binding domain-containing protein
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Large ribosomal subunit protein uL6 alpha-beta
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Schiff-base intermediate with acetaldehyde
Cytochrome b/b6 N-terminal region profile
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Large ribosomal subunit protein uL15/eL18
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Lipocalin/cytosolic fatty-acid binding domain-containing protein
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Thiamine pyrophosphate enzyme TPP-binding
Phosphoadenosine phosphosulphate reductase
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Aromatic amino acid beta-eliminating lyase/threonine aldolase
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Alpha-D-phosphohexomutase alpha/beta/alpha
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
N6 adenine-specific DNA methyltransferase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Prokaryotic-type class I peptide chain release factors
ATP synthase F1 complex delta/epsilon subunit N-terminal
Gram-positive pilin backbone subunit 2 Cna-B-like
Nucleophile; cysteine thiosulfonate intermediate
Cysteine sulfenic acid (-SOH) intermediate
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Phosphocysteine intermediate; for EIIB activity
Peptidase S9 prolyl oligopeptidase catalytic
PhoD-like phosphatase metallophosphatase
Phosphodiesterase/alkaline phosphatase D
Transposase IS204/IS1001/IS1096/IS1165 DDE
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
CobB/CobQ-like glutamine amidotransferase
Large ribosomal subunit protein uL2 C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Carbamoyl-phosphate synthase small subunit N-terminal
SGNH hydrolase-type esterase domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Reversibly protonated during proton transport
ABC-type glycine betaine transport system substrate-binding
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycosyltransferase subfamily 4-like N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Schiff-base intermediate with D-ribose 5-phosphate
Gram-positive cocci surface proteins LPxTG
Gram-positive cocci surface proteins LPxTG domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Penicillin-binding protein transpeptidase
Bacterial type II secretion system protein E
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Peptidase M1 membrane alanine aminopeptidase
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
NIF system FeS cluster assembly NifU N-terminal
Inner membrane protein YgaP-like transmembrane
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Release factor glutamine methyltransferase N-terminal
Anthranilate synthase component I N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Ribosome maturation factor RimP N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Translation elongation factor P/YeiP central
Bacterial bifunctional deaminase-reductase C-terminal
Excalibur calcium-binding domain-containing protein
Cell envelope-related transcriptional attenuator
Thymidylate synthase/dCMP hydroxymethylase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Positions MEP for the nucleophilic attack
Phosphotransferase system enzyme I N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
YbaK/aminoacyl-tRNA synthetase-associated
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Fe/B12 periplasmic-binding domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
DNA replication/recombination mediator RecO N-terminal
Small ribosomal subunit protein uS4 N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
ABC transporter substrate-binding protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Prepilin type IV endopeptidase peptidase
Involved in ionization of N3 of dUMP, leading to its activation
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
X-X-X-Leu-X-X-Gly heptad repeat-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Important for beta-aspartyl-AMP intermediate formation
LytR/CpsA/Psr regulator C-terminal domain-containing protein
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Glycosyl transferase family 3 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
MmyB-like transcription regulator ligand binding
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glycine cleavage T-protein C-terminal barrel
6-phosphogluconate dehydrogenase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Glycoside hydrolase family 3 N-terminal domain-containing protein