Resolvase/invertase-type recombinase catalytic
Major facilitator superfamily (MFS) profile
General stress protein FMN-binding split barrel
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Penicillin-binding protein transpeptidase
Translation elongation factor P/YeiP central
Solute-binding protein family 3/N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Solute-binding protein family 5 domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Glucosamine/galactosamine-6-phosphate isomerase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Acyl-CoA dehydrogenase/oxidase N-terminal
Tryptophan synthase beta chain-like PALP
Glycosyltransferase subfamily 4-like N-terminal
SUF system FeS cluster assembly SufBD N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Large ribosomal subunit protein uL2 C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
RNA 2-O ribose methyltransferase substrate binding
Alanyl-transfer RNA synthetases family profile
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Phosphatidic acid phosphatase type 2/haloperoxidase
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Thiamine pyrophosphate enzyme TPP-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Solute-binding protein family 3/N-terminal domain-containing protein
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Sodium/calcium exchanger membrane region
Small ribosomal subunit protein uS4 N-terminal
6-phosphogluconate dehydrogenase C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aminoacyl-transfer RNA synthetases class-II family profile
RNA polymerase sigma factor 70 region 4 type 2
Phosphatidate phosphatase APP1 catalytic
Sigma 54 modulation/S30EA ribosomal protein C-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Gly-cisPro motif, important for rejection of L-amino acids
Prepilin type IV endopeptidase peptidase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Exonuclease VII large subunit C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
CobB/CobQ-like glutamine amidotransferase
Ribosome maturation factor RimP N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Large ribosomal subunit protein uL15/eL18
Probable transposase IS891/IS1136/IS1341
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Phosphotransferase system enzyme I N-terminal
NIF system FeS cluster assembly NifU N-terminal
Inosine/uridine-preferring nucleoside hydrolase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
ABC-type glycine betaine transport system substrate-binding
Pseudouridine synthase I TruA alpha/beta
Pyruvate dehydrogenase E1 component middle
SGNH hydrolase-type esterase domain-containing protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Anthranilate synthase component I N-terminal
Prokaryotic-type class I peptide chain release factors
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
L,D-transpeptidase catalytic domain-containing protein
Nitrite/Sulfite reductase ferredoxin-like
Phenol hydroxylase C-terminal dimerisation
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Bacterial type II secretion system protein E
TRAP C4-dicarboxylate transport system permease DctM subunit
Peptidase S9 prolyl oligopeptidase catalytic
Phosphate starvation-inducible protein PhoH
Membrane insertase YidC/Oxa/ALB C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Carbamoyl-phosphate synthase small subunit N-terminal
Helix-hairpin-helix DNA-binding motif class 1
ABC transporter substrate-binding protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cation-transporting P-type ATPase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Peptide methionine sulphoxide reductase MsrA
Trigger factor ribosome-binding bacterial
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Cysteine sulfenic acid (-SOH) intermediate
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Alpha-D-phosphohexomutase alpha/beta/alpha
Essential for prephenate dehydratase activity
Heat-inducible transcription repressor HrcA C-terminal
4'-phosphopantetheinyl transferase N-terminal
Phosphoadenosine phosphosulphate reductase
Release factor glutamine methyltransferase N-terminal
PknH-like extracellular domain-containing protein
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Ribose-phosphate pyrophosphokinase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Nitrate ABC transporter substrate-binding protein
RNA binding; important for wobble base 34 recognition
Reversibly protonated during proton transport
S-adenosyl-L-homocysteine hydrolase NAD binding
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Electron transfer via tryptophanyl radical
Important for substrate specificity; cannot use PPi as phosphoryl donor
Nucleophile; cysteine thiosulfonate intermediate
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Sporulation transcription regulator WhiA N-terminal
Myo-inositol-1-phosphate synthase GAPDH-like
Important for beta-aspartyl-AMP intermediate formation
Acyl-CoA dehydrogenase/oxidase C-terminal
Periplasmic binding protein domain-containing protein
Peptidase M1 membrane alanine aminopeptidase
PhoD-like phosphatase metallophosphatase
Phosphodiesterase/alkaline phosphatase D
Meso-diaminopimelate D-dehydrogenase C-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Threonine/serine exporter-like N-terminal
Cytochrome C biogenesis protein transmembrane
Type II secretion system protein GspF domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Cobalamin-independent methionine synthase MetE N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Polymerase/histidinol phosphatase N-terminal
Cytochrome b/b6 N-terminal region profile
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Thymidylate synthase/dCMP hydroxymethylase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Phosphoribosylformylglycinamidine synthase linker
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Polysaccharide chain length determinant N-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Rv2525c-like glycoside hydrolase-like domain-containing protein
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Phosphomannose isomerase type I catalytic
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Superoxide dismutase copper/zinc binding
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
DNA replication/recombination mediator RecO N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Involved in ionization of N3 of dUMP, leading to its activation
Glycosyl transferase family 3 N-terminal
Ionotropic glutamate receptor C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Positions MEP for the nucleophilic attack
Endoribonuclease L-PSP/chorismate mutase-like
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL6 alpha-beta
Phospholipase/carboxylesterase/thioesterase domain-containing protein
Chromosomal replication initiator DnaA C-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Plays an important role in substrate specificity
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase