Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Endoribonuclease L-PSP/chorismate mutase-like
Inosine/uridine-preferring nucleoside hydrolase
Electron transfer via tryptophanyl radical
Pyridine nucleotide-disulphide oxidoreductase dimerisation
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Excalibur calcium-binding domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Peptidase M1 membrane alanine aminopeptidase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Glyoxalase/fosfomycin resistance/dioxygenase
Alanyl-transfer RNA synthetases family profile
Peptidase S9 prolyl oligopeptidase catalytic
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Ribosome maturation factor RimP N-terminal
Major facilitator superfamily (MFS) profile
4'-phosphopantetheinyl transferase N-terminal
Exonuclease VII large subunit C-terminal
Cytochrome C biogenesis protein transmembrane
Lactate utilization protein B C-terminal
Resolvase/invertase-type recombinase catalytic
RNA polymerase sigma factor 70 region 4 type 2
Cytochrome b/b6 N-terminal region profile
Aminoacyl-transfer RNA synthetases class-II family profile
Mandelate racemase/muconate lactonizing enzyme C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Could play a key role in the communication between the regulatory and the substrate sites
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Penicillin-binding protein transpeptidase
Glucosamine/galactosamine-6-phosphate isomerase
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phosphocysteine intermediate; for EIIB activity
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Translation elongation factor P/YeiP central
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribosomal RNA adenine methylase transferase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Tryptophan synthase beta chain-like PALP
Protocatechuate 3,4-dioxygenase beta subunit N-terminal
Plays an important role in substrate specificity
Inner membrane protein YgaP-like transmembrane
Schiff-base intermediate with substrate; via pyruvic acid
ABC-type glycine betaine transport system substrate-binding
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Important for substrate specificity; cannot use PPi as phosphoryl donor
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Reversibly protonated during proton transport
Cysteine sulfenic acid (-SOH) intermediate
Chromosomal replication initiator DnaA C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Cation-transporting P-type ATPase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Important for beta-aspartyl-AMP intermediate formation
Large ribosomal subunit protein uL6 alpha-beta
Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Maltose ABC transporter substrate-binding protein
Solute-binding protein family 3/N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Sodium/calcium exchanger membrane region
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Putative oxidoreductase/dehydrogenase Rossmann-like
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
Small ribosomal subunit protein uS4 N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycosyl transferase family 3 N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Polymerase/histidinol phosphatase N-terminal
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Carbamoyl-phosphate synthase small subunit N-terminal
RNA 2-O ribose methyltransferase substrate binding
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Polysaccharide chain length determinant N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Large ribosomal subunit protein uL15/eL18
Meso-diaminopimelate D-dehydrogenase C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Interaction with polymerase core subunit RpoC
Schiff-base intermediate with acetaldehyde
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
DNA replication/recombination mediator RecO N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Myo-inositol-1-phosphate synthase GAPDH-like
SUF system FeS cluster assembly SufBD N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Nitrite/Sulfite reductase ferredoxin-like
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Prepilin type IV endopeptidase peptidase
6-phosphogluconate dehydrogenase C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Heat-inducible transcription repressor HrcA C-terminal
Peptide methionine sulphoxide reductase MsrA
ABC transporter substrate-binding protein
Phosphomannose isomerase type I catalytic
Mycothiol-dependent maleylpyruvate isomerase metal-binding
O-(3'-phospho-DNA)-tyrosine intermediate
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glycine cleavage T-protein C-terminal barrel
Bacterial bifunctional deaminase-reductase C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Pseudouridine synthase I TruA alpha/beta
SGNH hydrolase-type esterase domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
RNA binding; important for wobble base 34 recognition
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Superoxide dismutase copper/zinc binding
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Pyruvate dehydrogenase E1 component middle
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Large ribosomal subunit protein uL2 C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Lipocalin/cytosolic fatty-acid binding domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
Cell wall-active antibiotics response LiaF-like C-terminal
Phosphatidate phosphatase APP1 catalytic
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Cobalamin-independent methionine synthase MetE N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Gly-cisPro motif, important for rejection of L-amino acids
Thymidylate synthase/dCMP hydroxymethylase
Membrane insertase YidC/Oxa/ALB C-terminal
Phosphoribosylformylglycinamidine synthase linker
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Cytochrome b561 bacterial/Ni-hydrogenase
Phosphatidic acid phosphatase type 2/haloperoxidase
Polysaccharide biosynthesis protein CapD-like
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
CobB/CobQ-like glutamine amidotransferase
Alpha-D-phosphohexomutase alpha/beta/alpha
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Aconitase A/isopropylmalate dehydratase small subunit swivel
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Activator of Hsp90 ATPase homologue 1-like C-terminal