Flavocytochrome c sulphide dehydrogenase flavin-binding
Disulphide bond isomerase DsbC/G N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
SAM-dependent methyltransferase TRM5/TYW2-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Glycosyl transferase family 3 N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Glucose-methanol-choline oxidoreductase N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Cob(I)alamin adenosyltransferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Bacterial type II secretion system protein E
Major facilitator superfamily (MFS) profile
Restriction system protein Mrr-like N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
RND efflux pump membrane fusion protein barrel-sandwich
Alpha-D-phosphohexomutase alpha/beta/alpha
Endolytic peptidoglycan transglycosylase RlpA
Mannose-6-phosphate isomerase type II C-terminal
Superoxide dismutase copper/zinc binding
Penicillin-binding protein transpeptidase
Caspase family p20 domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Chromosomal replication initiator DnaA C-terminal
Calcineurin-like phosphoesterase domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glycosyltransferase subfamily 4-like N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Thymidylate synthase/dCMP hydroxymethylase
Flagella basal body P-ring formation protein FlgA
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Aminoacyl-transfer RNA synthetases class-II family profile
Positions MEP for the nucleophilic attack
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Siroheme decarboxylase AsnC-like ligand binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Peptidase C14 caspase domain-containing protein
Tetrahydrodipicolinate-N-succinyltransferase chain A
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Interaction with polymerase core subunit RpoC
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
MalT-like TPR region domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Polymerase/histidinol phosphatase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Prepilin type IV endopeptidase peptidase
TonB-dependent receptor-like beta-barrel
Gamma-butyrobetaine hydroxylase-like N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Carbamoyl-phosphate synthase small subunit N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Urease accessory protein UreH-like transmembrane
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Plays an important role in substrate specificity
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Pyruvate/ketoisovalerate oxidoreductase catalytic
Thiol:disulfide interchange protein DsbD
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase-like C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
DNA replication/recombination mediator RecO N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
PHA accumulation regulator DNA-binding N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome b561 bacterial/Ni-hydrogenase
Translation elongation factor P/YeiP central
Pyridoxamine 5'-phosphate oxidase putative
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Inner membrane protein YgaP-like transmembrane
NADH:ubiquinone oxidoreductase 30kDa subunit
Membrane fusion protein biotin-lipoyl like
Phosphotransferase system enzyme I N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
UDP N-acetylglucosamine O-acyltransferase C-terminal
Important for interaction with partner proteins
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Leucine-binding protein domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Outer membrane protein assembly factor BamA
Protein-PII uridylyltransferase N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Type III secretion system flagellar brake protein YcgR PilZN
HicB-like antitoxin of toxin-antitoxin system
Large ribosomal subunit protein uL15/eL18
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Polysaccharide biosynthesis protein CapD-like
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Ribose-phosphate pyrophosphokinase N-terminal
Cysteine sulfenic acid (-SOH) intermediate
Doubled CXXCH motif domain-containing protein
Alanyl-transfer RNA synthetases family profile
N-end rule aminoacyl transferase C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Release factor glutamine methyltransferase N-terminal
Large ribosomal subunit protein uL2 C-terminal
Prokaryotic-type class I peptide chain release factors
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Peptidase M10 metallopeptidase domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Schiff-base intermediate with substrate; via pyruvic acid
NIF system FeS cluster assembly NifU N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Shikimate dehydrogenase substrate binding N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyruvate dehydrogenase E1 component middle
N-acetylneuraminic acid synthase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Adaptive response protein AidB N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Cytochrome b/b6 N-terminal region profile
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
DNA mismatch repair proteins mutS family
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Formylmethanofuran dehydrogenase subunit E
S-adenosyl-L-homocysteine hydrolase NAD binding
S-adenosylmethionine-dependent methyltransferase
Heme-copper oxidase subunit III family profile
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Glycine zipper 2TM domain-containing protein
ParB-related ThiF-related cassette protein E
O-(5'-phospho-DNA)-tyrosine intermediate
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Type IV pilus biogenesis and competence protein PilQ
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Important for beta-aspartyl-AMP intermediate formation
Survival protein SurE-like phosphatase/nucleotidase
Glycine cleavage T-protein C-terminal barrel
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Anthranilate synthase component I N-terminal
Exonuclease VII large subunit C-terminal
L-seryl-tRNA selenium transferase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Large ribosomal subunit protein uL6 alpha-beta
RNA 2-O ribose methyltransferase substrate binding
Solute-binding protein family 3/N-terminal
Flagellar motor switch protein FliN-like C-terminal
Electron transfer via tryptophanyl radical
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Trigger factor ribosome-binding bacterial
EfeO-type cupredoxin-like domain-containing protein
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Extradiol ring-cleavage dioxygenase LigAB LigA subunit
Peptide methionine sulphoxide reductase MsrA
Transcriptional regulator AbiEi antitoxin N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Aminoacyl-tRNA synthetase class I anticodon-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
DNA-directed DNA polymerase family A palm
Proton acceptor; for glutaminase activity
Essential for prephenate dehydratase activity
Important for substrate specificity; cannot use PPi as phosphoryl donor
Transcription factor NikR nickel binding C-terminal
Cation-transporting P-type ATPase N-terminal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein
Cytochrome c-type biogenesis protein CcmE
ABC-type transport auxiliary lipoprotein component
Pyruvate phosphate dikinase AMP/ATP-binding
Helix-hairpin-helix DNA-binding motif class 1
Could play a key role in the communication between the regulatory and the substrate sites
Cytochrome oxidase subunit II transmembrane region profile
RNA binding; important for wobble base 34 recognition
Cytochrome b/b6 C-terminal region profile
Cytochrome c-552/DMSO reductase-like haem-binding
Cytochrome c-552/DMSO reductase-like haem-binding domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Pseudouridine synthase I TruA alpha/beta
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Flagellar Assembly Protein A N-terminal region
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Sodium symporter small subunit predicted
Small ribosomal subunit protein uS4 N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Putative regulatory protein FmdB Zinc ribbon
Reversibly protonated during proton transport
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding