Alpha-D-phosphohexomutase alpha/beta/alpha
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
ATPsynthase alpha/beta subunit N-terminal extension
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Terminase large subunit-like endonuclease
Polymerase/histidinol phosphatase N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Flagellar Assembly Protein A N-terminal region
FAD-dependent oxidoreductase 2 FAD binding
Transcription regulator AsnC/Lrp ligand binding
Plays an important role in discriminating NADH against NADPH
RNA polymerase sigma factor 70 region 4 type 2
Phosphocysteine intermediate; for EIIB activity
Anthranilate synthase component I N-terminal
Alanyl-transfer RNA synthetases family profile
Polysaccharide chain length determinant N-terminal
Important for autoinhibition of adenylyltransferase activity
Large ribosomal subunit protein uL6 alpha-beta
Threonine/serine exporter-like N-terminal
Cation-transporting P-type ATPase N-terminal
Putative aromatic acid exporter C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Glycine cleavage T-protein C-terminal barrel
Penicillin-binding protein transpeptidase
Phosphoribosylformylglycinamidine synthase linker
Aminoacyl-transfer RNA synthetases class-II family profile
Prepilin type IV endopeptidase peptidase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
SsuA/THI5-like domain-containing protein
High-affinity heme uptake system protein IsdE
Flagellar motor switch protein FliN-like C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Important for beta-aspartyl-AMP intermediate formation
Major facilitator superfamily (MFS) profile
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Polysaccharide biosynthesis protein C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
DNA mismatch repair proteins mutS family
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Tryptophan synthase beta chain-like PALP
HNH/Endo VII superfamily nuclease toxins
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Dinitrogenase iron-molybdenum cofactor biosynthesis
Ribose-phosphate pyrophosphokinase N-terminal
Phosphomannose isomerase type I catalytic
Large ribosomal subunit protein uL15/eL18
RNA 2-O ribose methyltransferase substrate binding
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
YbaK/aminoacyl-tRNA synthetase-associated
Resolvase/invertase-type recombinase catalytic
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Bacterial type II secretion system protein E
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Glycosyltransferase subfamily 4-like N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Positions MEP for the nucleophilic attack
Gamma-glutamylcyclotransferase AIG2-like
Essential for prephenate dehydratase activity
Membrane fusion protein biotin-lipoyl like
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Solute-binding protein family 3/N-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
DNA-directed DNA polymerase family A palm
Translation elongation factor P/YeiP central
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Restriction system protein Mrr-like N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Cell envelope-related transcriptional attenuator
Pyrimidine nucleoside phosphorylase C-terminal
ABC transporter substrate-binding protein
Glycosyl hydrolase family 13 catalytic domain-containing protein
Release factor glutamine methyltransferase N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Glutathionylspermidine synthase pre-ATP-grasp-like
Probable transposase IS891/IS1136/IS1341
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Fatty acid kinase subunit A-like C-terminal
Important for interaction with partner proteins
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glycosyl transferase family 3 N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Could be important to modulate the pK values of the two catalytic cysteine residues
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Mannose-6-phosphate isomerase type II C-terminal
Interaction with polymerase core subunit RpoC
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Sortilin N-terminal domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Reversibly protonated during proton transport
Carbamoyl-phosphate synthase small subunit N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Plays an important role in substrate specificity
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein bL9 C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
AMP-activated protein kinase glycogen-binding
Polysaccharide biosynthesis protein CapD-like
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Large ribosomal subunit protein uL2 C-terminal
BREX system Lon protease-like BrxL N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
DNA polymerase III delta subunit C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Sodium/calcium exchanger membrane region
Diacylglycerol glucosyltransferase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Transposon Tn7 transposition protein TnsD C-terminal
Phosphoadenosine phosphosulphate reductase
Lysidine-tRNA(Ile) synthetase C-terminal
Peptidase M15C domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Phosphotransferase system enzyme I N-terminal
ABC transporter substrate-binding protein PnrA-like
Chromosomal replication initiator DnaA C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Type I restriction enzyme R protein N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Sporulation stage IV protein A C-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Bacterial bifunctional deaminase-reductase C-terminal
Important for substrate specificity; cannot use PPi as phosphoryl donor
Exonuclease VII large subunit C-terminal
Transcriptional regulator TetR C-terminal Firmicutes type
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Ribosomal RNA adenine methylase transferase N-terminal
Gram-positive cocci surface proteins LPxTG
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Choloylglycine hydrolase/NAAA C-terminal
Type VII secretion system protein EssD-like
Type VII secretion system protein EssD-like domain-containing protein
Proton acceptor; for glutaminase activity
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Pseudouridine synthase I TruA alpha/beta
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Thiamin pyrophosphokinase thiamin-binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
RNA binding; important for wobble base 34 recognition
Putative oxidoreductase/dehydrogenase Rossmann-like
Gly-cisPro motif, important for rejection of L-amino acids
Involved in allosteric activation by GTP
Septum formation inhibitor MinC C-terminal
Urease accessory protein UreH-like transmembrane
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
6-hydroxymethylpterin diphosphokinase MptE-like
Flagellar hook-length control protein-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
GxGYxYP putative glycoside hydrolase C-terminal
GxGYxYP putative glycoside hydrolase N-terminal