TRAP C4-dicarboxylate transport system permease DctM subunit
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Major facilitator superfamily (MFS) profile
Heat-inducible transcription repressor HrcA C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Bacterial DNA polymerase III alpha subunit NTPase
DNA polymerase helix-hairpin-helix motif
Prepilin type IV endopeptidase peptidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Transposase IS116/IS110/IS902 C-terminal
Alanyl-transfer RNA synthetases family profile
ABC-type glycine betaine transport system substrate-binding
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Putative component of 'biosynthetic module'
ABC transporter substrate-binding protein PnrA-like
Flagellar basal body rod protein N-terminal
Alpha-glycerophosphate oxidase C-terminal
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Flagellar basal-body/hook protein C-terminal
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein uL30-like ferredoxin-like fold
DNA replication/recombination mediator RecO N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Glycine cleavage T-protein C-terminal barrel
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Polysaccharide chain length determinant N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Schiff-base intermediate with acetaldehyde
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Menaquinone biosynthesis protein MenD middle
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
6-phosphogluconate dehydrogenase C-terminal
NIF system FeS cluster assembly NifU N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Conserved virulence factor B-like winged helix
Periplasmic copper-binding protein NosD beta helix
Calcineurin-like phosphoesterase domain-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Large ribosomal subunit protein uL2 C-terminal
Phosphomannose isomerase type I catalytic
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Gram-positive cocci surface proteins LPxTG
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Polymerase/histidinol phosphatase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Na+/H+ antiporter MnhB subunit-related protein
Cytochrome C biogenesis protein transmembrane
Carbamoyl-phosphate synthase small subunit N-terminal
Phosphoribosylformylglycinamidine synthase linker
Mannose-6-phosphate isomerase type II C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Tryptophan RNA-binding attenuator protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL6 alpha-beta
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Involved in allosteric activation by GTP
DNA mismatch repair proteins mutS family
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Penicillin-binding protein transpeptidase
Exonuclease VII large subunit C-terminal
Shikimate dehydrogenase substrate binding N-terminal
RNA polymerase sigma factor 70 region 4 type 2
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Tryptophan synthase beta chain-like PALP
Peptidase S9 prolyl oligopeptidase catalytic
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
D-galactarate/Altronate dehydratase C-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Superoxide dismutase copper/zinc binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Peptide methionine sulphoxide reductase MsrA
Signal transduction histidine kinase internal region
5-glutamyl coenzyme A thioester intermediate
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Cytochrome b/b6 N-terminal region profile
Chromosomal replication initiator DnaA C-terminal
Cation-transporting P-type ATPase N-terminal
Saccharopine dehydrogenase-like C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Polysaccharide biosynthesis protein C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Bacterial bifunctional deaminase-reductase C-terminal
Plays an important role in substrate specificity
Could play a key role in the communication between the regulatory and the substrate sites
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Phosphatidic acid phosphatase type 2/haloperoxidase
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Alpha-L-glutamate ligase-related protein ATP-grasp
RNA 2-O ribose methyltransferase substrate binding
Bacterial type II secretion system protein E
Phosphocysteine intermediate; for EIIB activity
YbaK/aminoacyl-tRNA synthetase-associated
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-111)
YbbR-like domain-containing protein YbbR
SUF system FeS cluster assembly SufBD N-terminal
Ionotropic glutamate receptor L-glutamate and glycine-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Schiff-base intermediate with dihydroxyacetone-P
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
S-adenosylmethionine-dependent methyltransferase
Resolvase/invertase-type recombinase catalytic
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Putative host cell surface-exposed lipoprotein Ltp-like HTH region
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Threonine/serine exporter-like N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
DNA-directed DNA polymerase family A palm
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
O-(3'-phospho-DNA)-tyrosine intermediate
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Sporulation transcription regulator WhiA N-terminal
May play a role in transmitting local conformational changes
Release factor glutamine methyltransferase N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Polysaccharide biosynthesis protein CapD-like
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Thiamin pyrophosphokinase thiamin-binding
Glycosyltransferase subfamily 4-like N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Flagellar motor switch protein FliN-like C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Excalibur calcium-binding domain-containing protein
Lysidine-tRNA(Ile) synthetase C-terminal
Cell envelope-related transcriptional attenuator
Alpha-D-phosphohexomutase alpha/beta/alpha
Thymidylate synthase/dCMP hydroxymethylase
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Involved in proton transfer during cleavage
NADH:flavin oxidoreductase/NADH oxidase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Small ribosomal subunit protein uS4 N-terminal
General stress protein FMN-binding split barrel
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Gamma-glutamylcyclotransferase AIG2-like
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
tRNA pseudouridylate synthase B C-terminal
Flagellar hook-length control protein-like C-terminal
Peptidase M1 membrane alanine aminopeptidase
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Sodium/calcium exchanger membrane region
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Reversibly protonated during proton transport
Aspartate/homoserine dehydrogenase NAD-binding
Pyrimidine nucleoside phosphorylase C-terminal
Putative aromatic acid exporter C-terminal
Kanamycin nucleotidyltransferase C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Transcriptional regulator SgrR N-terminal HTH
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Bacterial transcription activator effector binding
Ribose-phosphate pyrophosphokinase N-terminal
CobB/CobQ-like glutamine amidotransferase
Essential for prephenate dehydratase activity
Gly-cisPro motif, important for rejection of L-amino acids
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cytochrome b/b6 C-terminal region profile
Cell wall-active antibiotics response LiaF-like C-terminal
Anthranilate synthase component I N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Abortive infection protein-like C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Na+-translocating membrane potential-generating system MpsC
DNA polymerase III delta subunit C-terminal
Pseudouridine synthase I TruA alpha/beta
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Blue (type 1) copper domain-containing protein
Heme-copper oxidase subunit III family profile
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Elongation factor G-binding protein N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Intracellular proteinase inhibitor BsuPI
NIF system FeS cluster assembly NifU C-terminal
Positions MEP for the nucleophilic attack
Molybdopterin cofactor biosynthesis C (MoaC)
Interaction with polymerase core subunit RpoC
Schiff-base intermediate with D-ribose 5-phosphate
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Important for interaction with partner proteins
RNA binding; important for wobble base 34 recognition
Flagellar assembly protein FliH/Type III secretion system HrpE
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Glycosyl transferase family 3 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Prokaryotic-type class I peptide chain release factors
Phosphotransferase system enzyme I N-terminal
Transcriptional regulator LacI/GalR-like sensor
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Phage terminase large subunit C-terminal
Phage terminase large subunit N-terminal
Translation elongation factor P/YeiP central