Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Transglycosylase SLT domain-containing protein
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Pseudouridine synthase I TruA alpha/beta
Gamma-glutamylcyclotransferase AIG2-like domain-containing protein
Poly-beta-hydroxybutyrate polymerase N-terminal
Polysaccharide chain length determinant N-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Flagellar motor switch protein FliN-like C-terminal
Inner membrane protein YgaP-like transmembrane
YbhB/YbcL family Raf kinase inhibitor-like protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Outer membrane protein beta-barrel domain-containing protein
Proline utilization A proline dehydrogenase N-terminal
Alanyl-transfer RNA synthetases family profile
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
RNA 2-O ribose methyltransferase substrate binding
O-(phosphoribosyl dephospho-coenzyme A)serine
Type VI secretion system IcmF C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Release factor glutamine methyltransferase N-terminal
Organic solvent tolerance-like N-terminal
Anthranilate synthase component I N-terminal
Major facilitator superfamily (MFS) profile
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Prepilin type IV endopeptidase peptidase
Pyruvate phosphate dikinase AMP/ATP-binding
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Glycosyltransferase subfamily 4-like N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Peptidase S9 prolyl oligopeptidase catalytic
Tetrahydrodipicolinate-N-succinyltransferase chain A
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Ribosomal RNA adenine methylase transferase N-terminal
Elongation factor 1 beta central acidic region eukaryote
Aminoacyl-transfer RNA synthetases class-II family profile
Type II secretion system protein GspG C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NIF system FeS cluster assembly NifU N-terminal
DNA replication/recombination mediator RecO N-terminal
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Solute-binding protein family 3/N-terminal
Glycine zipper domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Flagella basal body P-ring formation protein FlgA C-terminal
Penicillin-binding protein transpeptidase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Exonuclease VII large subunit C-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Translocation and assembly module subunit TamA
DNA-directed DNA polymerase family A palm
Outer membrane protein OmpA-like transmembrane
Outer membrane protein OmpA-like transmembrane domain-containing protein
Membrane fusion protein biotin-lipoyl like
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Important for substrate binding and specificity
Plays an important role in discriminating NADH against NADPH
Prokaryotic-type class I peptide chain release factors
ssDNA thymidine ADP-ribosyltransferase DarT
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Thiamine pyrophosphate enzyme TPP-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Glucosamine/galactosamine-6-phosphate isomerase
Phosphoribosylformylglycinamidine synthase linker
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
RlpA-like protein double-psi beta-barrel
Flagella basal body P-ring formation protein FlgA
O-(5'-phospho-DNA)-tyrosine intermediate
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Conserved virulence factor B-like winged helix
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
UDP N-acetylglucosamine O-acyltransferase C-terminal
Tryptophan synthase beta chain-like PALP
Large ribosomal subunit protein uL15/eL18
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
SUF system FeS cluster assembly SufBD N-terminal
Resolvase/invertase-type recombinase catalytic
Adaptive response protein AidB N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
peptide-methionine (R)-S-oxide reductase
Reversibly protonated during proton transport
Bacterial type II secretion system protein E
Interaction with polymerase core subunit RpoC
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glycosyl transferase family 3 N-terminal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Sodium/calcium exchanger membrane region
Type IV secretion system coupling protein TraD DNA-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Outer membrane protein assembly factor BamD
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
N-acetylmuramoyl-L-alanine amidase domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Polysaccharide biosynthesis protein C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Integrating conjugative element protein PilL, PFGI-1 class
Gly-cisPro motif, important for rejection of L-amino acids
S-adenosyl-L-homocysteine hydrolase NAD binding
Cytochrome b561 bacterial/Ni-hydrogenase
Glycine cleavage T-protein C-terminal barrel
Putative regulatory protein FmdB Zinc ribbon
Outer-membrane lipoprotein carrier protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Helix-hairpin-helix DNA-binding motif class 1
Cytochrome c-type biogenesis protein CcmF C-terminal
Polymerase/histidinol phosphatase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Small ribosomal subunit protein uS4 N-terminal
Phosphoadenosine phosphosulphate reductase
Phosphatidylethanolamine-binding protein
Ionotropic glutamate receptor C-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Peptidase M12B domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Electron transfer via tryptophanyl radical
Autotransporter domain-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Type II secretion system protein GspC N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Thymidylate synthase/dCMP hydroxymethylase
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
DrrA phosphatidylinositol 4-phosphate binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Lysozyme inhibitor LprI N-terminal domain-containing protein
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Survival protein SurE-like phosphatase/nucleotidase
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Lipocalin-like domain-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Adenosine deaminase domain-containing protein
Type II secretion system protein GspI C-terminal
Saccharopine dehydrogenase-like C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Acyl-CoA dehydrogenase C-terminal bacterial-type
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Superoxide dismutase copper/zinc binding
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Flagellar hook-length control protein-like C-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
L,D-transpeptidase catalytic domain-containing protein
Arginine decarboxylase C-terminal helical
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Important for interaction with partner proteins
Outer membrane protein assembly factor BamA
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Polysaccharide biosynthesis protein CapD-like
Substrate of the Dot/Icm secretion system
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Alpha-D-phosphohexomutase alpha/beta/alpha
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL2 C-terminal
Chromosomal replication initiator protein DnaA
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Gamma-glutamylcyclotransferase AIG2-like
Pyrimidine nucleoside phosphorylase C-terminal
Plays an important role in substrate specificity
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Predicted pPIWI-associating nuclease group 2
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
3-beta hydroxysteroid dehydrogenase/isomerase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Type-F conjugative transfer system protein TraW N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Alpha-glycerophosphate oxidase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Pyruvate dehydrogenase E1 component middle
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Putative oxidoreductase/dehydrogenase Rossmann-like
DNA polymerase III subunit delta C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Signal recognition particle SRP54 helical bundle
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Membrane insertase YidC/Oxa/ALB C-terminal
Tellurite resistance methyltransferase TehB-like
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA mismatch repair proteins mutS family
Schiff-base intermediate with substrate; via pyruvic acid
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Bacterial transcription activator effector binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Choloylglycine hydrolase/NAAA C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Cation-transporting P-type ATPase N-terminal
Heme-copper oxidase subunit III family profile
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Endospore appendages core domain-containing protein