Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Prepilin type IV endopeptidase peptidase
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Alpha-D-phosphohexomutase alpha/beta/alpha
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Type VI secretion system IcmF C-terminal
Major facilitator superfamily (MFS) profile
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Chromosomal replication initiator protein DnaA
Release factor glutamine methyltransferase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
N6 adenine-specific DNA methyltransferase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
DNA-directed DNA polymerase family A palm
Aminoacyl-transfer RNA synthetases class-II family profile
Translation elongation factor P/YeiP central
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Prokaryotic-type class I peptide chain release factors
Cytochrome b561 bacterial/Ni-hydrogenase
Gp5/Type VI secretion system Vgr protein OB-fold
Putative type VI secretion system Rhs element associated Vgr
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Large ribosomal subunit protein uL15/eL18
Large ribosomal subunit protein uL6 alpha-beta
Pyruvate dehydrogenase E1 component middle
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Outer membrane protein assembly factor BamE
Important for interaction with partner proteins
Reversibly protonated during proton transport
Fe/B12 periplasmic-binding domain-containing protein
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Glycosyl transferase family 3 N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Gamma-butyrobetaine hydroxylase-like N-terminal
Small ribosomal subunit protein uS4 N-terminal
Phosphotransferase system enzyme I N-terminal
Exonuclease VII large subunit C-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Threonine/serine exporter-like N-terminal
Disulphide bond isomerase DsbC/G N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
S-adenosylmethionine-dependent methyltransferase
Outer-membrane lipoprotein carrier protein
O-(5'-phospho-DNA)-tyrosine intermediate
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Permuted papain-like amidase YaeF/Yiix C92 family enzyme
Autotransporter domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
DNA polymerase III delta subunit C-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA replication/recombination mediator RecO N-terminal
DNA polymerase III subunit delta C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyridoxamine 5'-phosphate oxidase putative
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Tetrahydrodipicolinate-N-succinyltransferase chain A
TonB-dependent receptor-like beta-barrel
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Tryptophan synthase beta chain-like PALP
Integral membrane protein YccS N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Anthranilate synthase component I N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Thymidylate synthase/dCMP hydroxymethylase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Positions MEP for the nucleophilic attack
RND efflux pump membrane fusion protein barrel-sandwich
NIF system FeS cluster assembly NifU N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Ribosomal RNA adenine methylase transferase N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Alanyl-transfer RNA synthetases family profile
Trimeric autotransporter adhesin YadA-like C-terminal membrane anchor
Trimeric autotransporter adhesin YadA-like head
Trimeric autotransporter adhesin YadA-like stalk
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
ATP synthase F1 complex delta/epsilon subunit N-terminal
4'-phosphopantetheinyl transferase N-terminal
Type III restriction enzyme C-terminal endonuclease
O-(3'-phospho-DNA)-tyrosine intermediate
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Nitrite/Sulfite reductase ferredoxin-like
Bacterial type II secretion system protein E
Penicillin-binding protein transpeptidase
Interaction with polymerase core subunit RpoC
Survival protein SurE-like phosphatase/nucleotidase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Pseudouridine synthase I TruA alpha/beta
ABC-type transport auxiliary lipoprotein component
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Peptidase S9 prolyl oligopeptidase catalytic
Plays an important role in substrate specificity
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Helix-hairpin-helix DNA-binding motif class 1
NADH:ubiquinone oxidoreductase 30kDa subunit
Virulence factor membrane-bound polymerase C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
YbaK/aminoacyl-tRNA synthetase-associated
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Inosine/uridine-preferring nucleoside hydrolase
Membrane fusion protein biotin-lipoyl like
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Polymerase/histidinol phosphatase N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Outer membrane protein assembly factor BamD
Cysteine sulfenic acid (-SOH) intermediate
Gly-cisPro motif, important for rejection of L-amino acids
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Aconitase A/isopropylmalate dehydratase small subunit swivel
HicB-like antitoxin of toxin-antitoxin system
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
HNH/Endo VII superfamily nuclease toxins
Large ribosomal subunit protein uL2 C-terminal
Essential for prephenate dehydratase activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Interacts with tRNA; defines subfamily-specific binding signature
Putative oxidoreductase/dehydrogenase Rossmann-like
Type 4 fimbrial biogenesis protein PilX N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Outer membrane component of tripartite multidrug resistance system
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
DNA-directed RNA polymerase RpoA/D/Rpb3-type
DNA mismatch repair proteins mutS family