N-end rule aminoacyl transferase C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Anthranilate synthase component I N-terminal
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
RND efflux pump membrane fusion protein barrel-sandwich
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Bacterial type II secretion system protein E
NADH:ubiquinone oxidoreductase 30kDa subunit
Glycosyl transferase family 3 N-terminal
Large ribosomal subunit protein uL15/eL18
DNA mismatch repair proteins mutS family
Flagellar basal-body/hook protein C-terminal
Urease accessory protein UreH-like transmembrane
Cytochrome c7-like domain-containing protein
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Cytochrome b561 bacterial/Ni-hydrogenase
Outer membrane protein assembly factor BamA
Glycine zipper 2TM domain-containing protein
Nitrite/Sulfite reductase ferredoxin-like
Cytochrome c-type biogenesis protein CcmF C-terminal
Major facilitator superfamily (MFS) profile
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
DNA-directed DNA polymerase family A palm
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Flagellar basal body rod protein N-terminal
Terminase large subunit-like endonuclease
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Schiff-base intermediate with substrate; via pyruvic acid
Transposase IS116/IS110/IS902 C-terminal
Nucleoside-binding outer membrane protein
Thymidylate synthase/dCMP hydroxymethylase
Survival protein SurE-like phosphatase/nucleotidase
Ribosomal RNA adenine methylase transferase N-terminal
Endolytic peptidoglycan transglycosylase RlpA
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Prokaryotic-type class I peptide chain release factors
CobB/CobQ-like glutamine amidotransferase
Activator of Hsp90 ATPase homologue 1-like C-terminal
Type II secretion system protein GspI C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
UDP N-acetylglucosamine O-acyltransferase C-terminal
Flagellar motor switch protein FliN-like C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Aminoacyl-transfer RNA synthetases class-II family profile
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Insecticide toxin TcdB middle/N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein uL2 C-terminal
Sodium/calcium exchanger membrane region
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Reversibly protonated during proton transport
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Increases nucleophilicity of active site Cys
Type II secretion system protein GspE N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Polymerase/histidinol phosphatase N-terminal
DNA replication/recombination mediator RecO N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
O-(5'-phospho-DNA)-tyrosine intermediate
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Large ribosomal subunit protein uL6 alpha-beta
Cysteine sulfenic acid (-SOH) intermediate
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
RNA 2-O ribose methyltransferase substrate binding
Glucosamine/galactosamine-6-phosphate isomerase
Type II secretion system protein GspG C-terminal
Required for zinc-mediated homotetramerization and catalytic activity
DNA polymerase III subunit delta C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
6-phosphogluconate dehydrogenase C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Aminoacyl-tRNA synthetase class I anticodon-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Mannose-6-phosphate isomerase type II C-terminal
Resolvase/invertase-type recombinase catalytic
Putative regulatory protein FmdB Zinc ribbon
Dinitrogenase iron-molybdenum cofactor N-terminal
Positions MEP for the nucleophilic attack
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Probable transposase IS891/IS1136/IS1341
Aconitase A/isopropylmalate dehydratase small subunit swivel
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glycine zipper domain-containing protein
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 2
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Penicillin-binding protein transpeptidase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Inner membrane protein YgaP-like transmembrane
NIF system FeS cluster assembly NifU N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Essential for prephenate dehydratase activity
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Could play a key role in the communication between the regulatory and the substrate sites
Thiol:disulfide interchange protein DsbD
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
glutathione gamma-glutamylcysteinyltransferase
Glycosyltransferase subfamily 4-like N-terminal
Solute-binding protein family 3/N-terminal
Terminase large subunit gp17-like C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Interaction with polymerase core subunit RpoC
Type IV pilus biogenesis and competence protein PilQ
Nitrogenase molybdenum-iron protein beta chain N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
Plays an important role in substrate specificity
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Glycoside hydrolase family 57 N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NIF system FeS cluster assembly NifU C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Type III secretion system flagellar brake protein YcgR PilZN
Type I restriction enzyme R protein N-terminal
Type I restriction modification DNA specificity
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Phosphotransferase system enzyme I N-terminal
Alanyl-transfer RNA synthetases family profile
Outer membrane protein beta-barrel domain-containing protein
Tryptophan synthase beta chain-like PALP
Important for interaction with partner proteins
Lytic transglycosylase superhelical linker
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Glycine cleavage T-protein C-terminal barrel
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Polysaccharide biosynthesis protein CapD-like
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
NADH-rubredoxin oxidoreductase C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Major facilitator superfamily associated
Outer membrane lipoprotein-sorting protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Dicarboxylate transport domain-containing protein
Sodium symporter small subunit predicted
Translation elongation factor P/YeiP central
Polysaccharide chain length determinant N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Release factor glutamine methyltransferase N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Membrane insertase YidC/Oxa/ALB C-terminal
Outer-membrane lipoprotein carrier protein
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Molybdopterin cofactor biosynthesis C (MoaC)
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pseudouridine synthase I TruA alpha/beta
Gamma-butyrobetaine hydroxylase-like N-terminal
RNA binding; important for wobble base 34 recognition
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cytochrome C Planctomycete-type domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
ABC-type uncharacterised transport system
Prepilin type IV endopeptidase peptidase
Could be important to modulate the pK values of the two catalytic cysteine residues
Exonuclease VII large subunit C-terminal
RNA polymerase sigma factor 70 region 4 type 2
ATP synthase F1 complex delta/epsilon subunit N-terminal
Flagellar hook-length control protein-like C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Tetrahydrodipicolinate-N-succinyltransferase chain A
Small ribosomal subunit protein uS4 N-terminal
Chromosomal replication initiator protein DnaA
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Type II restriction enzyme and methyltransferase RM.Eco57I-like
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Chromosomal replication initiator DnaA C-terminal