Ribose-phosphate pyrophosphokinase N-terminal
Cell envelope-related transcriptional attenuator
Glycosyltransferase subfamily 4-like N-terminal
DNA mismatch repair proteins mutS family
Schiff-base intermediate with acetaldehyde
Major facilitator superfamily (MFS) profile
Fibronectin type-III domain-containing protein
6-phosphogluconate dehydrogenase C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Right handed beta helix domain-containing protein
DNA replication/recombination mediator RecO N-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
DNA polymerase III beta sliding clamp C-terminal
Flagellar basal-body/hook protein C-terminal
Cation-transporting P-type ATPase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Important for interaction with partner proteins
Phosphatidic acid phosphatase type 2/haloperoxidase
Essential for prephenate dehydratase activity
Pyridoxamine 5'-phosphate oxidase putative
Gly-cisPro motif, important for rejection of L-amino acids
Phosphotransferase system enzyme I N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
General stress protein FMN-binding split barrel
Transcriptional regulator SgrR N-terminal HTH
Integron-associated effector binding protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Ribulose bisphosphate carboxylase large subunit C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Tryptophan synthase beta chain-like PALP
Glycosyl transferase family 3 N-terminal
SGNH hydrolase-type esterase domain-containing protein
Heme-copper oxidase subunit III family profile
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Signal transduction histidine kinase internal region
Signal recognition particle SRP54 helical bundle
Reversibly protonated during proton transport
6-phosphogluconate dehydrogenase NADP-binding
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Transposase IS116/IS110/IS902 C-terminal
Solute-binding protein family 3/N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
ABC transporter substrate-binding protein
Flagellar basal body rod protein N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Major facilitator superfamily associated
RNA 2-O ribose methyltransferase substrate binding
Phosphoribosylformylglycinamidine synthase linker
Aromatic amino acid beta-eliminating lyase/threonine aldolase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Sporulation stage IV protein A C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Polysaccharide biosynthesis protein C-terminal
Large ribosomal subunit protein uL2 C-terminal
Cytochrome b/b6 N-terminal region profile
RND efflux pump membrane fusion protein barrel-sandwich
Penicillin-binding protein transpeptidase
DNA-directed DNA polymerase family A palm
Large ribosomal subunit protein uL6 alpha-beta
Flagellar hook-length control protein-like C-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Alpha-D-phosphohexomutase alpha/beta/alpha
Copper amine oxidase-like N-terminal domain-containing protein
Peptidase M1 membrane alanine aminopeptidase
Glycoside hydrolase family 42 N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
tRNA pseudouridylate synthase B C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
Glycosyl hydrolase-like 10 domain-containing protein
Fe/B12 periplasmic-binding domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Superoxide dismutase copper/zinc binding
Aminoacyl-transfer RNA synthetases class-II family profile
Sporulation transcription regulator WhiA N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Polymerase/histidinol phosphatase N-terminal
Mannose-6-phosphate isomerase type II C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
May play a role in transmitting local conformational changes
Solute-binding protein family 3/N-terminal domain-containing protein
S-adenosylmethionine-dependent methyltransferase
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
NIF system FeS cluster assembly NifU N-terminal
Glycoside hydrolase family 3 N-terminal domain-containing protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Involved in allosteric activation by GTP
Protein-PII uridylyltransferase N-terminal
Glycoside hydrolase family 5 domain-containing protein
Polysaccharide biosynthesis protein CapD-like
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Small ribosomal subunit protein uS4 N-terminal
Alpha-glycerophosphate oxidase C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Cell wall-active antibiotics response LiaF-like C-terminal
Solute-binding protein family 5 domain-containing protein
Quercetin 2,3-dioxygenase C-terminal cupin
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Transcription regulator AsnC/Lrp ligand binding
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyridine nucleotide-disulphide oxidoreductase dimerisation
N-sulphoglucosamine sulphohydrolase C-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
SUF system FeS cluster assembly SufBD N-terminal
Transposon Tn7 transposition protein TnsD C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Large ribosomal subunit protein uL15/eL18
Interaction with polymerase core subunit RpoC
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Aconitase A/isopropylmalate dehydratase small subunit swivel
Pseudouridine synthase I TruA alpha/beta
Putative aromatic acid exporter C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Ribosomal RNA adenine methylase transferase N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Carbohydrate-binding domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Thymidylate synthase/dCMP hydroxymethylase
ABC transporter substrate-binding protein PnrA-like
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
SbsC C-terminal domain-containing protein
Peptidase G2 IMC autoproteolytic cleavage
Translation elongation factor P/YeiP central
Plays an important role in substrate specificity
Polysaccharide lyase 8 N-terminal alpha-helical
Polysaccharide lyase family 8 C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Saccharopine dehydrogenase-like C-terminal
Bacterial type II secretion system protein E
Alanyl-transfer RNA synthetases family profile
Cytochrome b/b6 C-terminal region profile
Endoribonuclease L-PSP/chorismate mutase-like
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Thiamin pyrophosphokinase thiamin-binding
Phosphocysteine intermediate; for EIIB activity
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Magnesium transporter MgtE intracellular
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Sugar ABC transporter substrate-binding protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
NADH:ubiquinone oxidoreductase-like 20kDa subunit
AraC-type arabinose-binding/dimerisation
Tellurite resistance methyltransferase TehB-like
D-galactose/methyl-galactoside binding periplasmic protein MglB
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Flagellar motor switch protein FliN-like C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Ionotropic glutamate receptor C-terminal
Ricin B lectin domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Polysaccharide chain length determinant N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Large ribosomal subunit protein bL9 C-terminal
Dipicolinate synthase subunit A N-terminal
Important for beta-aspartyl-AMP intermediate formation
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pyrimidine nucleoside phosphorylase C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Diacylglycerol glucosyltransferase N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Phosphomannose isomerase type I catalytic
Septum formation inhibitor MinC C-terminal
EfeO-type cupredoxin-like domain-containing protein
Pyruvate ferredoxin oxidoreductase beta subunit C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Na+-translocating membrane potential-generating system MpsC
Membrane insertase YidC/Oxa/ALB C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NIF system FeS cluster assembly NifU C-terminal
Helix-hairpin-helix DNA-binding motif class 1
RNA binding; important for wobble base 34 recognition
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Peptide methionine sulphoxide reductase MsrA
Spore germination GerAC-like C-terminal domain-containing protein
Cytochrome C biogenesis protein transmembrane
Glucosamine/galactosamine-6-phosphate isomerase
Chromosomal replication initiator DnaA C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Tryptophan RNA-binding attenuator protein
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Anthranilate synthase component I N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Mandelate racemase/muconate lactonizing enzyme C-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Carbamoyl-phosphate synthase small subunit N-terminal
Transcriptional regulator LacI/GalR-like sensor
Beta/gamma crystallin 'Greek key' domain-containing protein
Glyoxalase/fosfomycin resistance/dioxygenase
Schiff-base intermediate with D-ribose 5-phosphate
Flagellar Assembly Protein A N-terminal region
Ribonucleotide reductase large subunit C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Glycoside hydrolase family 31 N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Sodium/calcium exchanger membrane region
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Positions MEP for the nucleophilic attack
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic