TonB-dependent receptor-like beta-barrel
Glycine zipper 2TM domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
TRAP C4-dicarboxylate transport system permease DctM subunit
Phosphatidic acid phosphatase type 2/haloperoxidase
Glucose-methanol-choline oxidoreductase N-terminal
Major facilitator superfamily (MFS) profile
C-type lysozyme inhibitor domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
Mandelate racemase/muconate lactonizing enzyme C-terminal
Urease accessory protein UreH-like transmembrane
Thymidylate synthase/dCMP hydroxymethylase
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
PapC-like C-terminal domain-containing protein
Organic solvent tolerance-like N-terminal
Glucose-methanol-choline oxidoreductase C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Oxidoreductase molybdopterin-binding domain-containing protein
ABC transporter substrate-binding protein
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Solute-binding protein family 3/N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
Small ribosomal subunit protein uS4 N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
O-(5'-phospho-DNA)-tyrosine intermediate
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Outer membrane protein beta-barrel domain-containing protein
Flagellar motor switch protein FliN-like C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Gp5/Type VI secretion system Vgr protein OB-fold
Putative type VI secretion system Rhs element associated Vgr
Important for substrate binding and specificity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
PhoD-like phosphatase metallophosphatase
Peptidase S9 prolyl oligopeptidase catalytic
Outer membrane protein assembly factor BamD
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Alanyl-transfer RNA synthetases family profile
High potential iron-sulfur proteins family profile
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Integrative conjugative element protein, RAQPRD family
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Large ribosomal subunit protein uL2 C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Fe/B12 periplasmic-binding domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Translation elongation factor P/YeiP central
Flagellar hook-length control protein-like C-terminal
Membrane fusion protein biotin-lipoyl like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
UDP N-acetylglucosamine O-acyltransferase C-terminal
Alpha-glycerophosphate oxidase C-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Outer membrane protein assembly factor BamB
Mechanosensitive ion channel inner membrane
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
N6 adenine-specific DNA methyltransferase N-terminal
Peptide methionine sulphoxide reductase MsrA
Seems to be a necessary countercharge to the potassium cations
Peptide methionine sulfoxide reductase MsrA
Ribosomal RNA adenine methylase transferase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
AB hydrolase-1 domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
N-sulphoglucosamine sulphohydrolase C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Polymerase/histidinol phosphatase N-terminal
Electron transfer flavoprotein alpha subunit C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
ABC-type transport auxiliary lipoprotein component
SUF system FeS cluster assembly SufBD N-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Malonate/sodium symporter MadM subunit N-terminal
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Solute-binding protein family 5 domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glutathionylspermidine synthase pre-ATP-grasp-like
Type VI secretion system IcmF C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Prokaryotic-type class I peptide chain release factors
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glycosyltransferase subfamily 4-like N-terminal
MotA/TolQ/ExbB proton channel domain-containing protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Poly-beta-hydroxybutyrate polymerase N-terminal
Transglycosylase SLT domain-containing protein
C4-dicarboxylate ABC transporter substrate-binding protein
Interaction with polymerase core subunit RpoC
Acyl-CoA dehydrogenase/oxidase C-terminal
Adaptive response protein AidB N-terminal
Plays an important role in substrate specificity
Tripartite tricarboxylate transporter substrate binding protein
Dienelactone hydrolase domain-containing protein
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Phosphoadenosine phosphosulphate reductase
Tryptophan synthase beta chain-like PALP
Putative ATP-dependent zinc protease domain-containing protein
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Metallo-beta-lactamase domain-containing protein
Peptidase M20 dimerisation domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
SurA N-terminal domain-containing protein
Plays an important role in discriminating NADH against NADPH
CobB/CobQ-like glutamine amidotransferase
Electron transfer via tryptophanyl radical
3-keto-disaccharide hydrolase domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Involved in tetramerization or stability of the tetramer
Lysidine-tRNA(Ile) synthetase C-terminal
Sodium/calcium exchanger membrane region
SsuA/THI5-like domain-containing protein
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Thiol:disulfide interchange protein DsbD
BAAT/Acyl-CoA thioester hydrolase C-terminal
ABC-type glycine betaine transport system substrate-binding
Integrating conjugative element membrane protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
DNA polymerase III subunit delta C-terminal
Soluble ligand binding domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Aspartate/homoserine dehydrogenase NAD-binding
Gamma-glutamylcyclotransferase AIG2-like
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Putative regulatory protein FmdB Zinc ribbon
NIF system FeS cluster assembly NifU C-terminal
Arginine decarboxylase C-terminal helical
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Cytochrome c-type biogenesis protein CcmF C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Sodium symporter small subunit predicted
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Anthranilate synthase component I N-terminal
Penicillin-binding protein transpeptidase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Acyl-CoA dehydrogenase/oxidase N-terminal
Amino acid ABC transporter substrate-binding protein
Ionotropic glutamate receptor C-terminal
Heme-copper oxidase subunit III family profile
Release factor glutamine methyltransferase N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Solute-binding protein family 3/N-terminal domain-containing protein
Phosphocysteine intermediate; for EIIB activity
Glycine cleavage T-protein C-terminal barrel
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
DNA polymerase III delta subunit C-terminal
Peptidase M43 pregnancy-associated plasma-A
Shikimate dehydrogenase substrate binding N-terminal
Glucan biosynthesis periplasmic MdoG C-terminal
Glucan biosynthesis periplasmic MdoG C-terminal domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Glucosamine/galactosamine-6-phosphate isomerase
MmyB-like transcription regulator ligand binding
SGNH hydrolase-type esterase domain-containing protein
Helix-hairpin-helix DNA-binding motif class 1
PHA accumulation regulator DNA-binding N-terminal
Transcription regulator AsnC/Lrp ligand binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Important for interaction with partner proteins
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Saccharopine dehydrogenase-like C-terminal
Flagella basal body P-ring formation protein FlgA
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Disulphide bond isomerase DsbC/G N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Gamma-butyrobetaine hydroxylase-like N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Positions MEP for the nucleophilic attack
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Survival protein SurE-like phosphatase/nucleotidase
DNA-directed DNA polymerase family A palm
Type I restriction modification DNA specificity
Glycosyl transferase family 3 N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Reversibly protonated during proton transport
Type I restriction enzyme R protein N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Bacteriophage N4 adsorption protein A C-terminal
Bacteriophage N4 adsorption protein A C-terminal domain-containing protein
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Glucose/Sorbosone dehydrogenase domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
YbaK/aminoacyl-tRNA synthetase-associated
RNA polymerase sigma factor 70 region 4 type 2
Interacts with tRNA; defines subfamily-specific binding signature
Outer membrane lipoprotein carrier protein LolA
Chromosomal replication initiator protein DnaA
Gly-cisPro motif, important for rejection of L-amino acids
Nucleoside-binding outer membrane protein
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Pyrimidine nucleoside phosphorylase C-terminal
RNA binding; important for wobble base 34 recognition
Na+/H+ antiporter MnhB subunit-related protein
Acyl-CoA dehydrogenase C-terminal bacterial-type
N-end rule aminoacyl transferase C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead domain-containing protein
Large ribosomal subunit protein uL15/eL18
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Metal ABC transporter substrate-binding protein
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Lipopolysaccharide export system protein LptA
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Proton acceptor; for glutaminase activity
Activator of Hsp90 ATPase homologue 1-like C-terminal
Moybdenum cofactor oxidoreductase dimerisation
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Exonuclease VII large subunit C-terminal
Pyruvate dehydrogenase E1 component middle
Spore coat protein U domain-containing protein
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Pili assembly chaperone N-terminal domain-containing protein
CD-NTase-associated protein 12/Pycsar effector protein TIR
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Bacterial type II secretion system protein E
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Pyruvate phosphate dikinase AMP/ATP-binding
Acetylserotonin O-methyltransferase dimerisation
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cytochrome c-552/4 domain-containing protein
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Flagellar assembly protein FliH/Type III secretion system HrpE
Chromosomal replication initiator DnaA C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Phosphonate ABC transporter substrate-binding protein
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Sugar fermentation stimulation protein C-terminal
Essential for prephenate dehydratase activity
Guanylate kinase/L-type calcium channel beta subunit
DNA replication/recombination mediator RecO N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Transcription elongation factor GreA/GreB N-terminal
Bacterial surface antigen (D15) domain-containing protein