Prokaryotic-type class I peptide chain release factors
TonB-dependent receptor-like beta-barrel
Alpha-L-rhamnosidase six-hairpin glycosidase
Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein
Bacterial alpha-L-rhamnosidase N-terminal
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
N-sulphoglucosamine sulphohydrolase C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Bacterial surface antigen (D15) domain-containing protein
Activator of Hsp90 ATPase homologue 1-like C-terminal
Major facilitator superfamily (MFS) profile
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
RNA polymerase sigma factor 70 region 4 type 2
Polymerase/histidinol phosphatase N-terminal
Proton acceptor; for glutaminase activity
Polysaccharide biosynthesis protein CapD-like
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
SusC/RagA family TonB-linked outer membrane protein
Tail specific protease domain-containing protein
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Outer membrane protein beta-barrel domain-containing protein
Glycosyl-hydrolase 97 C-terminal oligomerisation
Phosphoribosylformylglycinamidine synthase linker
ATP synthase F1 complex delta/epsilon subunit N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Tryptophan synthase beta chain-like PALP
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Glycine cleavage T-protein C-terminal barrel
Signal transduction histidine kinase internal region
Glycosyl hydrolase-like 10 domain-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
DNA replication/recombination mediator RecO N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Glycosyltransferase subfamily 4-like N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Right handed beta helix domain-containing protein
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Translation elongation factor P/YeiP central
Polysaccharide biosynthesis protein C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Lysidine-tRNA(Ile) synthetase C-terminal
DNA mismatch repair proteins mutS family
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Pyrroline-5-carboxylate reductase catalytic N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
LamG-like jellyroll fold domain-containing protein
Type I restriction enzyme R protein N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
3-keto-disaccharide hydrolase domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Ribonucleotide reductase class II vitamin B12-dependent N-terminal
Ribonucleotide reductase large subunit C-terminal
Heme-copper oxidase subunit III family profile
Peptidase M1 membrane alanine aminopeptidase
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Penicillin-binding protein transpeptidase
Reversibly protonated during proton transport
TerB family tellurite resistance protein
Chromosomal replication initiator DnaA C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
C-type lysozyme inhibitor domain-containing protein
6-phosphogluconate dehydrogenase C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Gp5/Type VI secretion system Vgr protein OB-fold
TonB C-terminal domain-containing protein
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
RNA binding; important for wobble base 34 recognition
Alpha/beta hydrolase fold-3 domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Polysaccharide lyase family 8 C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Cytochrome c-552/4 domain-containing protein
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Glucosamine/galactosamine-6-phosphate isomerase
Leucine-binding protein domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
ATP-grasp fold succinyl-CoA synthetase-type
Histidine kinase domain-containing protein
Sialate O-acetylesterase domain-containing protein
NADH:ubiquinone oxidoreductase 30kDa subunit
Aromatic amino acid beta-eliminating lyase/threonine aldolase
RNA 2-O ribose methyltransferase substrate binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Polysaccharide lyase 8 N-terminal alpha-helical
T9SS C-terminal target domain-containing protein
Gfo/Idh/MocA-like oxidoreductase C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Anthranilate synthase component I N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Transposase IS116/IS110/IS902 C-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Shikimate dehydrogenase substrate binding N-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
TonB-dependent receptor plug domain-containing protein
Polysaccharide chain length determinant N-terminal
Carbohydrate-binding domain-containing protein
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Small ribosomal subunit protein uS4 N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Endonuclease/exonuclease/phosphatase domain-containing protein
Large ribosomal subunit protein uL15/eL18
Cysteine sulfenic acid (-SOH) intermediate
AB hydrolase-1 domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Peptidoglycan recognition protein family
Trigger factor ribosome-binding bacterial
Large ribosomal subunit protein uL2 C-terminal
Beta-lactamase-related domain-containing protein
Glycosyl hydrolase family 30 beta sandwich
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Glycoside hydrolase 123 C-terminal domain-containing protein
YbaK/aminoacyl-tRNA synthetase-associated
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Fibronectin type-III domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Phosphatidylglycerol lysyltransferase C-terminal
Superoxide dismutase copper/zinc binding
Pyruvate phosphate dikinase AMP/ATP-binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Sodium/calcium exchanger membrane region
Glycoside hydrolase family 42 N-terminal
tRNA pseudouridylate synthase B C-terminal
ATP-dependent DNA helicase RecG C-terminal
Peptide methionine sulfoxide reductase MsrB
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Amidohydrolase-related domain-containing protein
Glycosyl hydrolases family 2 sugar binding domain-containing protein
Putative adhesin domain-containing protein
Ribosomal RNA adenine methylase transferase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Acyltransferase MbtK/IucB-like conserved
Xylose isomerase-like TIM barrel domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Molybdopterin cofactor biosynthesis C (MoaC)
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Type I restriction modification DNA specificity
Aspartate/homoserine dehydrogenase NAD-binding
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glycosyl-hydrolase family 116 catalytic region
Glycosyl-hydrolase family 116 catalytic region domain-containing protein
Pyrroline-5-carboxylate reductase dimerisation
Schiff-base intermediate with substrate; via pyruvic acid
Aminoacyl-tRNA synthetase class I anticodon-binding
O-(5'-phospho-DNA)-tyrosine intermediate
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Type II and III secretion system protein
Saccharopine dehydrogenase-like C-terminal
Glycoside hydrolase family 13 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
SusD/RagB family nutrient-binding outer membrane lipoprotein
Lipocalin-like domain-containing protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Thiamine pyrophosphate enzyme TPP-binding
Glycoside hydrolase family 38 N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glycoside hydrolase family 49 N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Large ribosomal subunit protein uL6 alpha-beta
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
RlpA-like protein double-psi beta-barrel
Alpha galactosidase C-terminal beta sandwich
Cationic amino acid transporter C-terminal
Glycoside hydrolase 123 N-terminal domain-containing protein
Carbamoyl-phosphate synthase small subunit N-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Glycosyl-hydrolase family 116 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Schiff-base intermediate with acetaldehyde
Lysozyme inhibitor LprI N-terminal domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Beta-hexosaminidase bacterial type N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Positions MEP for the nucleophilic attack
Phosphatidic acid phosphatase type 2/haloperoxidase
Survival protein SurE-like phosphatase/nucleotidase
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
S-adenosyl-L-homocysteine hydrolase NAD binding
Membrane fusion protein biotin-lipoyl like
N6 adenine-specific DNA methyltransferase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
FAD-binding PCMH-type domain-containing protein
UDP N-acetylglucosamine O-acyltransferase C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)
Urease accessory protein UreH-like transmembrane
Phosphomannose isomerase type I catalytic
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Glycoside hydrolase family 31 N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
NADH-rubredoxin oxidoreductase C-terminal
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Cytochrome C biogenesis protein transmembrane
SGNH hydrolase-type esterase domain-containing protein
Contractile injection system tube protein N-terminal
Alginate lyase domain-containing protein
Inward rectifier potassium channel C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Pyruvate/ketoisovalerate oxidoreductase catalytic
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Peptidase M17 leucyl aminopeptidase N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Plays an important role in substrate specificity
Alpha-glycerophosphate oxidase C-terminal
Organic solvent tolerance-like N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Pseudouridine synthase I TruA alpha/beta
Bacterial type II secretion system protein E
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Helix-hairpin-helix DNA-binding motif class 1
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Acyltransferase 3 domain-containing protein
Beta-glucuronidase C-terminal domain-containing protein
DNA-directed DNA polymerase family A palm
Transglutaminase-like domain-containing protein