Chemotaxis methyl-accepting receptor HlyB-like 4HB MCP
Carbamoyl-phosphate synthase small subunit N-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Inosine/uridine-preferring nucleoside hydrolase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
SusD/RagB family nutrient-binding outer membrane lipoprotein
Beta-hexosaminidase bacterial type N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Signal transduction histidine kinase internal region
Outer membrane protein beta-barrel domain-containing protein
Peptidoglycan recognition protein family
TonB-dependent receptor-like beta-barrel
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Secretion system C-terminal sorting domain-containing protein
Peptidase M1 membrane alanine aminopeptidase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Major facilitator superfamily (MFS) profile
Glycosyltransferase subfamily 4-like N-terminal
Penicillin-binding protein transpeptidase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
RNA polymerase sigma factor 70 region 4 type 2
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Helix-hairpin-helix DNA-binding motif class 1
Gfo/Idh/MocA-like oxidoreductase bacterial type C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glucosamine/galactosamine-6-phosphate isomerase
NADH:ubiquinone oxidoreductase 30kDa subunit
Transition state stabilizer; via amide nitrogen
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Polysaccharide biosynthesis protein C-terminal
Putative adhesin domain-containing protein
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Gly-cisPro motif, important for rejection of L-amino acids
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Glycosyl transferase family 3 N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
TonB C-terminal domain-containing protein
Heme-copper oxidase subunit III family profile
3-keto-disaccharide hydrolase domain-containing protein
Arsenosugar biosynthesis radical SAM protein ArsS-like C-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Important for interaction with partner proteins
Glycine cleavage T-protein C-terminal barrel
Moybdenum cofactor oxidoreductase dimerisation
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Putative exodeoxyribonuclease 8 PDDEXK-like
Alpha-glycerophosphate oxidase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Curlin associated repeat-containing protein
RND efflux pump membrane fusion protein barrel-sandwich
tRNA pseudouridylate synthase B C-terminal
Saccharopine dehydrogenase-like C-terminal
PhoD-like phosphatase metallophosphatase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Anthranilate synthase component I N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Histidine-specific methyltransferase SAM-dependent
Bacterial bifunctional deaminase-reductase C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
NIF system FeS cluster assembly NifU C-terminal
Shikimate dehydrogenase substrate binding N-terminal
RNA binding; important for wobble base 34 recognition
SUF system FeS cluster assembly SufBD N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Carboxypeptidase regulatory-like domain-containing protein
Type I restriction enzyme R protein N-terminal
Carboxypeptidase-like regulatory domain-containing protein
Curli production assembly/transport component CsgF
Esterase-like activity of phytase family protein
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Right handed beta helix domain-containing protein
Cyclophilin-like domain-containing protein
Pectate lyase superfamily protein domain-containing protein
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Nitrite/Sulfite reductase ferredoxin-like
DNA mismatch repair proteins mutS family
Amidohydrolase-related domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
Peptidase C14 caspase catalytic subunit p20
Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein
Pili assembly chaperone N-terminal domain-containing protein
Biopterin-dependent aromatic amino acid hydroxylase family profile
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Tryptophan synthase beta chain-like PALP
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Proton acceptor; for glutaminase activity
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Lipocalin-like domain-containing protein
Beta-lactamase-inhibitor-like PepSY-like domain-containing protein
ABC-type uncharacterised transport system
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Membrane fusion protein biotin-lipoyl like
Sortilin N-terminal domain-containing protein
RlpA-like protein double-psi beta-barrel
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyrroline-5-carboxylate reductase catalytic N-terminal
Sialate O-acetylesterase domain-containing protein
Polysaccharide chain length determinant N-terminal
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Inner membrane protein YgaP-like transmembrane
Copper type II ascorbate-dependent monooxygenase C-terminal
Copper type II ascorbate-dependent monooxygenase C-terminal domain-containing protein
Molybdopterin cofactor biosynthesis C (MoaC)
Twin-arginine translocation pathway signal
Glycine zipper domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Beta-xylosidase C-terminal Concanavalin A-like
Serine aminopeptidase S33 domain-containing protein
Thiopeptide-type bacteriocin biosynthesis
Thymidylate synthase/dCMP hydroxymethylase
N6 adenine-specific DNA methyltransferase N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Gluconate 2-dehydrogenase subunit 3 family protein
Bacterial transcription activator effector binding
S-adenosyl-L-homocysteine hydrolase NAD binding
NADH-rubredoxin oxidoreductase C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Release factor glutamine methyltransferase N-terminal
Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein
Antitoxin Xre/MbcA/ParS-like toxin-binding
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Putative oxidoreductase/dehydrogenase Rossmann-like
Peptidase S9 prolyl oligopeptidase catalytic
Glycoside hydrolase family 13 N-terminal
Translation elongation factor P/YeiP central
Trigger factor ribosome-binding bacterial
Polysaccharide pyruvyl transferase domain-containing protein
Glycosyl hydrolase BNR repeat-containing protein
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
6-phosphogluconate dehydrogenase C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Sphingolipid delta4-desaturase N-terminal
Type I restriction modification DNA specificity
Plays an important role in maintaining the position of the catalytic nucleophile
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Collagen triple helix repeat-containing protein
Peptidase M17 leucyl aminopeptidase N-terminal
Electron transfer via tryptophanyl radical
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Important for autoinhibition of adenylyltransferase activity
Cationic amino acid transporter C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glycoside hydrolase GH146 substrate-binding
Glycoside hydrolase GH146 substrate-binding domain-containing protein
Peptidase M43 pregnancy-associated plasma-A
Aconitase A/isopropylmalate dehydratase small subunit swivel
Exonuclease VII large subunit C-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Organic solvent tolerance-like N-terminal
Organic solvent tolerance-like N-terminal domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
S-adenosylmethionine-dependent methyltransferase
Peptidase S12 Pab87-related C-terminal domain-containing protein
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Plays an important role in substrate specificity
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-118)
Phosphomannose isomerase type I catalytic
Resolvase/invertase-type recombinase catalytic
Putative beta-lactamase-inhibitor-like PepSY-like
Putative beta-lactamase-inhibitor-like PepSY-like domain-containing protein
Translation elongation factor EFTs/EF1B dimerisation
Quercetin 2,3-dioxygenase C-terminal cupin
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Membrane protein involved in aromatic hydrocarbon degradation
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Gp5/Type VI secretion system Vgr protein OB-fold
General stress protein FMN-binding split barrel
Electron transfer flavoprotein alpha/beta-subunit N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Activator of Hsp90 ATPase homologue 1-like C-terminal
Glycerophosphoryl diester phosphodiesterase membrane
Mandelate racemase/muconate lactonizing enzyme C-terminal
DNA topoisomerase I catalytic core eukaryotic-type
Outer membrane lipoprotein-sorting protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Prokaryotic-type class I peptide chain release factors
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
ParB-related ThiF-related cassette protein E
Large ribosomal subunit protein uL6 alpha-beta
Water stress and hypersensitive response
Phage terminase large subunit C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Chromosomal replication initiator DnaA C-terminal
Large ribosomal subunit protein uL2 C-terminal
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Positions MEP for the nucleophilic attack
DNA replication/recombination mediator RecO N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Limiting CO2-inducible protein B/C beta carbonyic anhydrase
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Beta-lactamase-related domain-containing protein
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Curli production assembly/transport component CsgE
Probable transposase IS891/IS1136/IS1341
Gamma-glutamylcyclotransferase AIG2-like
Polysaccharide biosynthesis protein CapD-like
Cytochrome c-type biogenesis protein CcmF C-terminal
DNA-directed DNA polymerase family A palm
N-end rule aminoacyl transferase C-terminal
Ppx/GppA phosphatase domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Murein L,D-transpeptidase catalytic domain family protein
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
TtsA-like Glycoside hydrolase family 108
Inward rectifier potassium channel C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Type IX secretion system protein PorV domain-containing protein
Glycosyl hydrolase family 30 beta sandwich
Schiff-base intermediate with substrate; via pyruvic acid
Membrane insertase YidC/Oxa/ALB C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glycosyl-hydrolase 97 C-terminal oligomerisation
Thiamine pyrophosphate enzyme N-terminal TPP-binding
peptide-methionine (R)-S-oxide reductase
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Schiff-base intermediate with acetaldehyde
Pyrroline-5-carboxylate reductase dimerisation
Cysteine sulfenic acid (-SOH) intermediate
Type IX secretion system membrane protein PorP/SprF
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Glycoside hydrolase family 42 N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Phage terminase large subunit N-terminal
SGNH hydrolase-type esterase domain-containing protein
Auto-transporter adhesin head GIN domain-containing protein
Alanyl-transfer RNA synthetases family profile
Sulfatase-modifying factor enzyme domain-containing protein
Could be important to modulate the pK values of the two catalytic cysteine residues
Beta-lactamase class A catalytic domain-containing protein
Alginate lyase domain-containing protein
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Polymerase/histidinol phosphatase N-terminal
Haem-binding uptake Tiki superfamily ChaN
Lysidine-tRNA(Ile) synthetase C-terminal
Small ribosomal subunit protein uS4 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Calcineurin-like phosphoesterase C-terminal
Calcineurin-like phosphoesterase N-terminal
Reversibly protonated during proton transport
Thiamin pyrophosphokinase thiamin-binding
Large ribosomal subunit protein uL15/eL18
Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein
Gliding motility-associated protein GldM C-terminal
Gliding motility-associated protein GldM N-terminal
Pseudouridine synthase I TruA alpha/beta
Survival protein SurE-like phosphatase/nucleotidase
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain