Ribosomal RNA adenine methylase transferase N-terminal
Transposase IS204/IS1001/IS1096/IS1165 DDE
Small ribosomal subunit protein uS4 N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Type IV pili methyl-accepting chemotaxis transducer N-term
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glucose-methanol-choline oxidoreductase N-terminal
Sec translocon accessory complex subunit YajC
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Solute-binding protein family 3/N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Aminoacyl-transfer RNA synthetases class-II family profile
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Major facilitator superfamily (MFS) profile
Nitrite/Sulfite reductase ferredoxin-like
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Tryptophan synthase beta chain-like PALP
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Transferrin-binding protein B C-lobe/N-lobe beta barrel domain-containing protein
Flagellar basal body rod protein N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Solute-binding protein family 3/N-terminal domain-containing protein
Flagellar basal-body/hook protein C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Glycine zipper domain-containing protein
TRAP C4-dicarboxylate transport system permease DctM subunit
Bacterial bifunctional deaminase-reductase C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Sodium symporter small subunit predicted
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Type II secretion system protein GspC N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Alanyl-transfer RNA synthetases family profile
RNA 2-O ribose methyltransferase substrate binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
PEP-CTERM protein-sorting domain-containing protein
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
DNA mismatch repair proteins mutS family
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Required for zinc-mediated homotetramerization and catalytic activity
Outer membrane protein assembly factor BamD
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Membrane fusion protein biotin-lipoyl like
Bacterial type II secretion system protein E
Alpha-D-phosphohexomutase alpha/beta/alpha
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Molybdopterin cofactor biosynthesis C (MoaC)
O-(5'-phospho-DNA)-tyrosine intermediate
Urease accessory protein UreH-like transmembrane
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
DNA replication/recombination mediator RecO N-terminal
Siroheme decarboxylase AsnC-like ligand binding
Translation elongation factor P/YeiP central
Cytochrome C biogenesis protein transmembrane
Outer membrane protein assembly factor BamA
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glycoside hydrolase family 57 N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Glucan biosynthesis periplasmic MdoG C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Tricarboxylic transport membrane protein
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
RNA methyltransferase SpoU/TrmH type C-terminal
Fe/B12 periplasmic-binding domain-containing protein
Large ribosomal subunit protein uL15/eL18
ABC-type glycine betaine transport system substrate-binding
Outer membrane protein beta-barrel domain-containing protein
Type VI secretion system lipoprotein TssJ
N6 adenine-specific DNA methyltransferase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
PhoD-like phosphatase metallophosphatase
NADH-rubredoxin oxidoreductase C-terminal
RNA binding; important for wobble base 34 recognition
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Aerobactin siderophore biosynthesis IucA/IucC N-terminal
Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glucose-methanol-choline oxidoreductase C-terminal
Release factor glutamine methyltransferase N-terminal
Beta-lactamase hydrolase-like protein phosphatase-like
Penicillin-binding protein transpeptidase
Positions MEP for the nucleophilic attack
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
L,D-transpeptidase catalytic domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Peptide methionine sulphoxide reductase MsrA
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Heme-copper oxidase subunit III family profile
Acyl-CoA dehydrogenase C-terminal bacterial-type
Transglycosylase SLT domain-containing protein
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Polymerase/histidinol phosphatase N-terminal
ABC-type transport auxiliary lipoprotein component
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
CobB/CobQ-like glutamine amidotransferase
YbaK/aminoacyl-tRNA synthetase-associated
Murein L,D-transpeptidase catalytic domain family protein
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Inner membrane protein YgaP-like transmembrane
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Acetyl-CoA hydrolase/transferase C-terminal
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Regulator of nucleoside diphosphate kinase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Prepilin type IV endopeptidase peptidase
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
TonB-dependent receptor-like beta-barrel
Survival protein SurE-like phosphatase/nucleotidase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Thiamin/hydroxymethyl pyrimidine-binding YkoF putative
Outer membrane lipoprotein BamD-like domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Glycosyl transferase family 3 N-terminal
Abnormal spindle-like microcephaly-associated protein ASH
Choice-of-anchor D domain-containing protein
Putative beta-barrel assembly-enhancing protease
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Type II restriction endonuclease EcoO109IR
CASTOR/POLLUX/SYM8 ion channel conserved
Penicillin-binding protein activator LpoB
Cytochrome c-type biogenesis protein CcmF C-terminal
Interaction with polymerase core subunit RpoC
Peptidoglycan binding-like domain-containing protein
Zinc-regulated TonB-dependent outer membrane receptor
5-methyltetrahydrofolate--homocysteine methyltransferase
Poly-beta-hydroxybutyrate polymerase N-terminal
Pseudouridine synthase I TruA alpha/beta
Moybdenum cofactor oxidoreductase dimerisation
Sodium/calcium exchanger membrane region
Flagellar motor switch protein FliN-like C-terminal
Electron transfer via tryptophanyl radical
Mandelate racemase/muconate lactonizing enzyme C-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Important for interaction with partner proteins
Putative regulatory protein FmdB Zinc ribbon
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
Cytochrome b561 bacterial/Ni-hydrogenase
Antitoxin Xre/MbcA/ParS-like toxin-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Haem-binding uptake Tiki superfamily ChaN
Thymidylate synthase/dCMP hydroxymethylase
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Phosphatidylglycerol lysyltransferase C-terminal
Transcription elongation factor GreA/GreB N-terminal
Leucine-binding protein domain-containing protein
Anthranilate synthase component I N-terminal
DNA polymerase III subunit delta C-terminal
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Ionotropic glutamate receptor C-terminal
Haemolysin activator HlyB C-terminal domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
N-end rule aminoacyl transferase C-terminal
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain-containing protein
Gp5/Type VI secretion system Vgr protein OB-fold
PrcB C-terminal domain-containing protein
Proline utilization A proline dehydrogenase N-terminal
Ribonucleotide reductase large subunit C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
NAD(P) transhydrogenase alpha subunit C-terminal
Glycoside-hydrolase family GH114 TIM-barrel
Disulphide bond isomerase DsbC/G N-terminal
Phospholipid transport system substrate-binding protein
Important for beta-aspartyl-AMP intermediate formation
4'-phosphopantetheinyl transferase N-terminal
Putative ATP-dependent zinc protease domain-containing protein
Polysaccharide biosynthesis protein C-terminal
Dicarboxylate transport domain-containing protein
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Cation-transporting P-type ATPase N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Plays an important role in substrate specificity
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Prokaryotic-type class I peptide chain release factors
Alpha-glycerophosphate oxidase C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Bacterial virulence factor lipase N-terminal domain-containing protein
Flagellar hook-length control protein-like C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
SUF system FeS cluster assembly SufBD N-terminal
Polysaccharide biosynthesis protein CapD-like
Peptidase S9 prolyl oligopeptidase catalytic
Proton acceptor; for glutaminase activity
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Essential for prephenate dehydratase activity
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
NIF system FeS cluster assembly NifU C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Chromosomal replication initiator protein DnaA
Tripartite tricarboxylate transporter substrate binding protein
Reversibly protonated during proton transport
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Endonuclease/exonuclease/phosphatase domain-containing protein
Secreted protein containing HslJ-like protein
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Large ribosomal subunit protein uL2 C-terminal
PQQ-dependent catabolism-associated beta-propeller protein
Organic solvent ABC transporter permease
Type II secretion system protein GspI C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding