Ribosomal RNA adenine methylase transferase N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Cysteine sulfenic acid (-SOH) intermediate
Heme-copper oxidase subunit III family profile
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Transcription factor NikR nickel binding C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
O-(5'-phospho-DNA)-tyrosine intermediate
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Interaction with polymerase core subunit RpoC
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Important for interaction with partner proteins
PEP-CTERM protein-sorting domain-containing protein
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Type ISP restriction-modification enzyme LLaBIII C-terminal specificity
Pseudouridine synthase I TruA alpha/beta
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Reversibly protonated during proton transport
Positions MEP for the nucleophilic attack
Flagellar motor switch protein FliN-like C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
DNA-directed DNA polymerase family A palm
Major facilitator superfamily (MFS) profile
Cytochrome b561 bacterial/Ni-hydrogenase
Chromosomal replication initiator DnaA C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Alpha-D-phosphohexomutase alpha/beta/alpha
Cache 3/Cache 2 fusion domain-containing protein
Alpha-amylase/4-alpha-glucanotransferase C-terminal
Alpha-amylase/4-alpha-glucanotransferase central
Glycoside hydrolase family 57 N-terminal
Large ribosomal subunit protein uL15/eL18
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Inner membrane protein YgaP-like transmembrane
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Helix-hairpin-helix DNA-binding motif class 1
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Polymerase/histidinol phosphatase N-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Prepilin type IV endopeptidase peptidase
RNA polymerase sigma factor 70 region 4 type 2
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Could play a key role in the communication between the regulatory and the substrate sites
Nitrite/Sulfite reductase ferredoxin-like
Large ribosomal subunit protein uL2 C-terminal
HicB-like antitoxin of toxin-antitoxin system
Prokaryotic-type class I peptide chain release factors
Small ribosomal subunit protein uS4 N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Release factor glutamine methyltransferase N-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Tellurite resistance methyltransferase TehB-like
Antitoxin Xre/MbcA/ParS-like toxin-binding
RND efflux pump membrane fusion protein barrel-sandwich
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Cytochrome c-552/DMSO reductase-like haem-binding
Formylmethanofuran dehydrogenase subunit E
Survival protein SurE-like phosphatase/nucleotidase
Glycosyltransferase subfamily 4-like N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Large ribosomal subunit protein uL6 alpha-beta
Bacterial type II secretion system protein E
Siroheme decarboxylase AsnC-like ligand binding
Polysaccharide biosynthesis protein CapD-like
TRAP C4-dicarboxylate transport system permease DctM subunit
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
RNA 2-O ribose methyltransferase substrate binding
Molybdopterin cofactor biosynthesis C (MoaC)
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Penicillin-binding protein transpeptidase
Exonuclease VII large subunit C-terminal
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Type II secretion system protein GspG C-terminal
ABC-type transport auxiliary lipoprotein component
Outer membrane protein beta-barrel domain-containing protein
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Tryptophan synthase beta chain-like PALP
Chromosomal replication initiator protein DnaA
Proton acceptor; for glutaminase activity
Metallo-beta-lactamase domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Important for beta-aspartyl-AMP intermediate formation
O-(3'-phospho-DNA)-tyrosine intermediate
Glycosyl transferase family 3 N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Right handed beta helix domain-containing protein
Phosphotransferase system enzyme I N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Membrane fusion protein biotin-lipoyl like
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Ribose-phosphate pyrophosphokinase N-terminal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Translocation and assembly module subunit TamA
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Carbamoyl-phosphate synthase small subunit N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Type III secretion system flagellar brake protein YcgR PilZN
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
ATP synthase F1 complex delta/epsilon subunit N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Aconitase A/isopropylmalate dehydratase small subunit swivel
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
NIF system FeS cluster assembly NifU N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Membrane insertase YidC/Oxa/ALB C-terminal
TIGR02281 family clan AA aspartic protease
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
ABC-type uncharacterised transport system
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Lytic transglycosylase superhelical linker
NADH-rubredoxin oxidoreductase C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Pyridoxamine 5'-phosphate oxidase putative
VPLPA-CTERM sorting domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Periplasmic copper-binding protein NosD beta helix
Type II secretion system protein GspI C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Cytochrome C biogenesis protein transmembrane
Pyruvate dehydrogenase E1 component middle
Solute-binding protein family 3/N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
DNA replication/recombination mediator RecO N-terminal
Outer membrane lipoprotein-sorting protein
Essential for prephenate dehydratase activity
Outer membrane protein assembly factor BamA
Heat-inducible transcription repressor HrcA C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Gfo/Idh/MocA-like oxidoreductase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Phosphatidic acid phosphatase type 2/haloperoxidase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
TonB-dependent receptor-like beta-barrel
Ribulose bisphosphate carboxylase small subunit
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Alanyl-transfer RNA synthetases family profile
Opioid growth factor receptor (OGFr) conserved
Mannose-6-phosphate isomerase type II C-terminal
Flavocytochrome c sulphide dehydrogenase flavin-binding
RHS repeat-associated core domain-containing protein
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Cytochrome oxidase subunit II copper A binding
Cation-transporting P-type ATPase N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
S-adenosylmethionine-dependent methyltransferase
UDP N-acetylglucosamine O-acyltransferase C-terminal
Thiol:disulfide interchange protein DsbD
DNA polymerase III subunit delta C-terminal
Schiff-base intermediate with substrate; via pyruvic acid
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Glycine zipper 2TM domain-containing protein
Polysaccharide chain length determinant N-terminal
Outer membrane protein assembly factor BamE
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Cytochrome oxidase subunit II transmembrane region profile
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
NADH:ubiquinone oxidoreductase chain 4 N-terminal
6-phosphogluconate dehydrogenase C-terminal
Peptide methionine sulphoxide reductase MsrA
PilC beta-propeller domain-containing protein
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Secretion system X translation initiation factor
Cytochrome c-type biogenesis protein CcmF C-terminal
Glycine cleavage T-protein C-terminal barrel
Disulphide bond isomerase DsbC/G N-terminal
ABC-type transport auxiliary lipoprotein component domain-containing protein
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Translation elongation factor P/YeiP central
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Resolvase/invertase-type recombinase catalytic
Required for zinc-mediated homotetramerization and catalytic activity
Anthranilate synthase component I N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Restriction system protein Mrr-like N-terminal
Lipopolysaccharide export system protein LptA
Organic solvent tolerance-like N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Major facilitator superfamily associated
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Type I restriction modification DNA specificity
Plays an important role in substrate specificity
Sodium symporter small subunit predicted
UPF0173 metal-dependent hydrolase SCD_n01867
Tetrahydrodipicolinate-N-succinyltransferase chain A
Phosphoadenosine phosphosulphate reductase
Flagellar assembly protein FliH/Type III secretion system HrpE
Periplasmic nitrate reductase, electron transfer subunit
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity