RNA polymerase sigma factor 70 region 4 type 2
Important for beta-aspartyl-AMP intermediate formation
Transglutaminase-like domain-containing protein
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
O-(5'-phospho-DNA)-tyrosine intermediate
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Chromosomal replication initiator DnaA C-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Glycyl cysteine dithioester (Cys-Gly) (interchain with G-Cter in ThiS)
Gram-positive cocci surface proteins LPxTG domain-containing protein
Phosphotransferase system enzyme I N-terminal
Terminase large subunit-like endonuclease
Aminoacyl-transfer RNA synthetases class-II family profile
Polysaccharide chain length determinant N-terminal
Transposase IS116/IS110/IS902 C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
ABC transporter substrate-binding protein PnrA-like
Cell envelope-related transcriptional attenuator
Resolvase/invertase-type recombinase catalytic
Fibronectin type-III domain-containing protein
Efflux RND transporter periplasmic adaptor subunit
Sporulation stage II protein D amidase enhancer LytB N-terminal
Cation-transporting P-type ATPase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Sporulation initiation factor Spo0A C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Membrane fusion protein biotin-lipoyl like
Peptidase C39-like domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Glycosyl transferase family 3 N-terminal
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Small ribosomal subunit protein uS4 N-terminal
Inosine monophosphate cyclohydrolase-like
YbaK/aminoacyl-tRNA synthetase-associated
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Plays an important role in substrate specificity
Glycoside hydrolase family 31 N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
SGNH hydrolase-type esterase domain-containing protein
Exonuclease VII large subunit C-terminal
Translation elongation factor P/YeiP central
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL2 C-terminal
Essential for prephenate dehydratase activity
Carbohydrate binding module 65 domain-containing protein
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Saccharopine dehydrogenase-like C-terminal
Transcriptional coactivator p15 (PC4) C-terminal
Prepilin type IV endopeptidase peptidase
Phosphatidic acid phosphatase type 2/haloperoxidase
BAAT/Acyl-CoA thioester hydrolase C-terminal
PsbP C-terminal domain-containing protein
Proton acceptor; for glutaminase activity
Aconitase A/isopropylmalate dehydratase small subunit swivel
Tryptophan synthase beta chain-like PALP
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Aspartate/homoserine dehydrogenase NAD-binding
Phosphocysteine intermediate; for EIIB activity
Prokaryotic-type class I peptide chain release factors
Bacterial type II secretion system protein E
Ribose-phosphate pyrophosphokinase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
Penicillin-binding protein transpeptidase
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Gly-cisPro motif, important for rejection of L-amino acids
Putative amidase domain-containing protein
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
ATP-dependent DNA helicase RecG C-terminal
DNA-directed DNA polymerase family A palm
Choloylglycine hydrolase/NAAA C-terminal
RNA 2-O ribose methyltransferase substrate binding
Release factor glutamine methyltransferase N-terminal
Sporulation stage IV protein A C-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Terminase large subunit gp17-like C-terminal
Polysaccharide biosynthesis protein C-terminal
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Could play a key role in the communication between the regulatory and the substrate sites
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Reversibly protonated during proton transport
Type I restriction modification DNA specificity
Dipicolinate synthase subunit A N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Solute-binding protein family 3/N-terminal
Prealbumin-like fold domain-containing protein
N6 adenine-specific DNA methyltransferase N-terminal
Pseudouridine synthase I TruA alpha/beta
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Interaction with polymerase core subunit RpoC
Polysaccharide biosynthesis protein CapD-like
RND efflux pump membrane fusion protein barrel-sandwich
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Important for substrate specificity; cannot use PPi as phosphoryl donor
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Ribosome maturation factor RimP N-terminal
DNA mismatch repair proteins mutS family
Large ribosomal subunit protein uL15/eL18
Helix-hairpin-helix DNA-binding motif class 1
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Alanyl-transfer RNA synthetases family profile
Membrane insertase YidC/Oxa/ALB C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Translation elongation factor EFTs/EF1B dimerisation
Anthranilate synthase component I N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Important for autoinhibition of adenylyltransferase activity
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyruvate/ketoisovalerate oxidoreductase catalytic
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Alpha-D-phosphohexomutase alpha/beta/alpha
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Bacterial toxin 44 domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Cadherin-like beta sandwich domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
HicB-like antitoxin of toxin-antitoxin system
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Signal recognition particle SRP54 helical bundle
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Thiamin pyrophosphokinase thiamin-binding
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Gram-positive cocci surface proteins LPxTG
Sugar fermentation stimulation protein C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Threonine/serine exporter-like N-terminal
NIF system FeS cluster assembly NifU N-terminal
Cobalamin-independent methionine synthase MetE N-terminal
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 2
DNA-directed RNA polymerase RpoA/D/Rpb3-type
CobB/CobQ-like glutamine amidotransferase
Phosphoribosylformylglycinamidine synthase linker
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
ATPsynthase alpha/beta subunit N-terminal extension
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Phosphomannose isomerase type I catalytic
Microcystin LR degradation protein MlrC N-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor