AB hydrolase-1 domain-containing protein
TRAP transporter solute receptor, TAXI family
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Major facilitator superfamily (MFS) profile
Prokaryotic-type class I peptide chain release factors
Solute-binding protein family 3/N-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Phosphatidic acid phosphatase type 2/haloperoxidase
Transposase IS116/IS110/IS902 C-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
O-(3'-phospho-DNA)-tyrosine intermediate
Glycoside hydrolase family 42 N-terminal
Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis
YbaK/aminoacyl-tRNA synthetase-associated
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
2-oxoacid dehydrogenase acyltransferase catalytic
Alginate biosynthesis protein AlgX C-terminal carbohydrate-binding module
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glycosyltransferase subfamily 4-like N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Exonuclease VII large subunit C-terminal
Type II secretion system protein GspC N-terminal
Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Outer-membrane lipoprotein carrier protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Cytochrome b561 bacterial/Ni-hydrogenase
RND efflux pump membrane fusion protein barrel-sandwich
Na(+)-translocating NADH-quinone reductase subunit A C-terminal
Organic solvent tolerance-like N-terminal
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Alginate export domain-containing protein
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Cysteine sulfenic acid (-SOH) intermediate
Glycine cleavage T-protein C-terminal barrel
Sugar fermentation stimulation protein C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Carbamoyl-phosphate synthase small subunit N-terminal
Flagellar hook-length control protein-like C-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Survival protein SurE-like phosphatase/nucleotidase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Transposase IS204/IS1001/IS1096/IS1165 DDE
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Important for autoinhibition of adenylyltransferase activity
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Phosphoadenosine phosphosulphate reductase
ABC-type glycine betaine transport system substrate-binding
Bacterial type II secretion system protein E
Membrane fusion protein biotin-lipoyl like
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Heme-copper oxidase subunit III family profile
TIGR03756 family integrating conjugative element protein
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
NIF system FeS cluster assembly NifU N-terminal
Glutamate synthase alpha subunit C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Type II secretion system protein GspG C-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
Release factor glutamine methyltransferase N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Ribonucleotide reductase large subunit C-terminal
Membrane-bound lytic murein transglycosylase A
Adaptive response protein AidB N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Cytochrome oxidase subunit II copper A binding
3-isopropylmalate dehydratase large subunit
Mechanosensitive ion channel inner membrane
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Periplasmic binding protein domain-containing protein
Reversibly protonated during proton transport
Disulphide bond isomerase DsbC/G N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Prepilin type IV endopeptidase peptidase
Type III restriction enzyme C-terminal endonuclease
Large ribosomal subunit protein uL6 alpha-beta
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Putative conjugal transfer nickase/helicase TraI C-terminal
Tryptophan synthase beta chain-like PALP
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)
Plays an important role in substrate specificity
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Peptidase M61 catalytic domain-containing protein
DNA polymerase III delta subunit C-terminal
NADH:ubiquinone oxidoreductase 49 kD subunit 7
Aspartate/homoserine dehydrogenase NAD-binding
Essential for prephenate dehydratase activity
Gfo/Idh/MocA-like oxidoreductase N-terminal
Endolytic peptidoglycan transglycosylase RlpA
Urease accessory protein UreH-like transmembrane
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Periplasmic nitrate reductase, electron transfer subunit
Poly-beta-hydroxybutyrate polymerase N-terminal
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
N-acetylneuraminic acid synthase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Small ribosomal subunit protein uS4 N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
TonB-dependent receptor-like beta-barrel
Cation-transporting P-type ATPase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Glycosyl transferase family 3 N-terminal
DNA-directed DNA polymerase family A palm
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aminoacyl-tRNA synthetase class I anticodon-binding
Peptidase C39-like domain-containing protein
Na+/H+ antiporter MnhB subunit-related protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Polymerase/histidinol phosphatase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Large ribosomal subunit protein uL2 C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Anthranilate synthase component I N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Transcription elongation factor GreA/GreB C-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Inner membrane protein YgaP-like transmembrane
NIF system FeS cluster assembly NifU C-terminal
Positions MEP for the nucleophilic attack
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
L-seryl-tRNA selenium transferase N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
UDP N-acetylglucosamine O-acyltransferase C-terminal
Integral membrane protein YccS N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
ABC-type transport auxiliary lipoprotein component
UDP-glucose/GDP-mannose dehydrogenase C-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
Peptide methionine sulphoxide reductase MsrA
Quinohemoprotein amine dehydrogenase gamma subunit structural
For 3-hydroxyacyl-CoA dehydrogenase activity
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Putative Flp pilus-assembly TadG-like N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Quercetin 2,3-dioxygenase C-terminal cupin
Major facilitator superfamily associated
5-glutamyl coenzyme A thioester intermediate
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Penicillin-binding protein transpeptidase
Outer membrane protein assembly factor BamA
Pyruvate dehydrogenase E1 component middle
Thiol:disulfide interchange protein DsbD
Alanyl-transfer RNA synthetases family profile
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Proline utilization A proline dehydrogenase N-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Cytochrome c-type biogenesis protein CcmF C-terminal
Type II secretion system protein TadB-like N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Important for beta-aspartyl-AMP intermediate formation
Phosphoethanolamine transferase N-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
TIGR03757 family integrating conjugative element protein
Antitoxin Xre/MbcA/ParS-like toxin-binding
Translation elongation factor P/YeiP central
S-adenosylmethionine-dependent methyltransferase
Membrane insertase YidC/Oxa/ALB C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Flagellar motor switch protein FliN-like C-terminal
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Transcription elongation factor GreA/GreB N-terminal
Alpha-glycerophosphate oxidase C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Putative beta-barrel assembly-enhancing protease
NADH:ubiquinone oxidoreductase 30kDa subunit
Cob(I)alamin adenosyltransferase N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Putative ATP-dependent zinc protease domain-containing protein
Lytic transglycosylase superhelical linker
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Chromosomal replication initiator protein DnaA
4'-phosphopantetheinyl transferase N-terminal
Important for interaction with partner proteins
Ionotropic glutamate receptor C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Mannose-6-phosphate isomerase type II C-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Signal transduction histidine kinase internal region
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Interaction with polymerase core subunit RpoC
Aldehyde oxidase/xanthine dehydrogenase first molybdopterin binding
Aldehyde oxidase/xanthine dehydrogenase second molybdopterin binding
Curli production assembly/transport component CsgE
DNA primase/polymerase bifunctional N-terminal
YMGG-like Gly-zipper domain-containing protein
Type II secretion system protein GspI C-terminal
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Translation initiation factor 2 (IF-2, GTPase)
Outer membrane lipoprotein-sorting protein
DNA polymerase III subunit delta C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Pseudouridine synthase I TruA alpha/beta
HicB-like antitoxin of toxin-antitoxin system
Leucine-binding protein domain-containing protein
Interacts with tRNA; defines subfamily-specific binding signature
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Polysaccharide biosynthesis protein CapD-like
Molybdenum cofactor biosynthesis protein F N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
DNA replication/recombination mediator RecO N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Lipoprotein YgdI/YgdR-like SH3-like domain-containing protein
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Flagellar assembly protein FliH/Type III secretion system HrpE
Transcriptional regulator AbiEi antitoxin N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Terminase large subunit gp17-like C-terminal
Seems to be a necessary countercharge to the potassium cations
Alpha-D-phosphohexomutase alpha/beta/alpha
Lactate utilization protein B C-terminal
Important for substrate binding and specificity
Nucleophile; cysteine thiosulfonate intermediate
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
CobB/CobQ-like glutamine amidotransferase
Malonate/sodium symporter MadM subunit N-terminal
Proton acceptor; for glutaminase activity
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
DNA-3-methyladenine glycosylase AlkA N-terminal
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Guanylate kinase/L-type calcium channel beta subunit
S-adenosyl-L-homocysteine hydrolase NAD binding
Thymidylate synthase/dCMP hydroxymethylase
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Arginine decarboxylase C-terminal helical
Pyruvate phosphate dikinase AMP/ATP-binding
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Curli production assembly/transport component CsgF
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Styrene monooxygenase StyA putative substrate binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Acyl-CoA dehydrogenase C-terminal bacterial-type
Cytochrome C biogenesis protein transmembrane
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Electron transfer via tryptophanyl radical
Hydroquinone 1,2-dioxygenase large subunit N-terminal
Water stress and hypersensitive response
Regulator of nucleoside diphosphate kinase N-terminal
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Polypeptide-transport-associated ShlB-type
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Integrating conjugative element membrane protein
Lipopolysaccharide export system protein LptA
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
ATP synthase F1 complex delta/epsilon subunit N-terminal
Required for dimer formation and molybdate binding
Bacterial OB-fold domain-containing protein