Pyridoxamine kinase/Phosphomethylpyrimidine kinase
O-(3'-phospho-DNA)-tyrosine intermediate
DNA primase/polymerase bifunctional N-terminal
Major facilitator superfamily (MFS) profile
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Helix-turn-helix conjugative transposon-like
Large ribosomal subunit protein uL6 alpha-beta
Transposase IS204/IS1001/IS1096/IS1165 DDE
Transposase IS204/IS1001/IS1096/IS1165 helix-turn-helix
Transposase IS204/IS1001/IS1096/IS1165 zinc-finger
Transposase IS116/IS110/IS902 C-terminal
Important for beta-aspartyl-AMP intermediate formation
Polymerase/histidinol phosphatase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
X-Prolyl dipeptidyl aminopeptidase PepX N-terminal
Plays an important role in substrate specificity
Ribosomal RNA adenine methylase transferase N-terminal
SUF system FeS cluster assembly SufBD N-terminal
HicB-like antitoxin of toxin-antitoxin system
tRNA pseudouridylate synthase B C-terminal
Type VII secretion system protein EssD-like
Large ribosomal subunit protein uL15/eL18
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Aminoacyl-transfer RNA synthetases class-II family profile
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Cation-transporting P-type ATPase N-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
DNA-directed RNA polymerase RpoA/D/Rpb3-type
O-(phosphoribosyl dephospho-coenzyme A)serine
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Transcriptional regulator LacI/GalR-like sensor
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Gfo/Idh/MocA-like oxidoreductase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Prokaryotic-type class I peptide chain release factors
Terminase large subunit-like endonuclease
Reversibly protonated during proton transport
Bacterial bifunctional deaminase-reductase C-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Solute-binding protein family 3/N-terminal
DNA replication/recombination mediator RecO N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Positions ribitol 5-phosphate for the nucleophilic attack
Alanyl-transfer RNA synthetases family profile
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Phosphotransferase system EIIB component type 2/3
Conserved virulence factor B-like winged helix
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Peptidase M1 membrane alanine aminopeptidase
Important for interaction with partner proteins
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
N6 adenine-specific DNA methyltransferase N-terminal
Gram-positive cocci surface proteins LPxTG domain-containing protein
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
Translation elongation factor P/YeiP central
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Peptide methionine sulphoxide reductase MsrA
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Phosphocysteine intermediate; for EIIB activity
Glucosamine/galactosamine-6-phosphate isomerase
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Solute-binding protein family 5 domain-containing protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Pseudouridine synthase I TruA alpha/beta
RNA binding; important for wobble base 34 recognition
Alpha-D-phosphohexomutase alpha/beta/alpha
Large ribosomal subunit protein uL2 C-terminal
Exonuclease VII large subunit C-terminal
Tryptophan synthase beta chain-like PALP
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Gram-positive cocci surface proteins LPxTG
Gram-positive pilin subunit D1 N-terminal
Arabinogalactan endo-beta-1,4-galactanase
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Phosphomannose isomerase type I catalytic
Penicillin-binding protein transpeptidase
6-phosphogluconate dehydrogenase C-terminal
Alpha-L-rhamnosidase six-hairpin glycosidase
Signal recognition particle SRP54 helical bundle
Sporulation transcription regulator WhiA N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Resolvase/invertase-type recombinase catalytic
ABC transmembrane type-1 domain-containing protein
Helix-hairpin-helix DNA-binding motif class 1
RNA 2-O ribose methyltransferase substrate binding
Phosphatidic acid phosphatase type 2/haloperoxidase
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Thymidylate synthase/dCMP hydroxymethylase
Chromosomal replication initiator DnaA C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
CobB/CobQ-like glutamine amidotransferase
Type VII secretion system protein EssD-like domain-containing protein
Inosine/uridine-preferring nucleoside hydrolase
NIF system FeS cluster assembly NifU N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Release factor glutamine methyltransferase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Peptidase C39-like domain-containing protein
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
DNA mismatch repair proteins mutS family
Bacterial type II secretion system protein E
Involved in allosteric activation by GTP
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glycosyltransferase subfamily 4-like N-terminal
Cell wall-active antibiotics response LiaF-like C-terminal
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
ABC-type glycine betaine transport system substrate-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Type III restriction/modification enzyme methylation subunit
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Phosphotransferase system enzyme I N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Sigma 54 modulation/S30EA ribosomal protein C-terminal