Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Gly-cisPro motif, important for rejection of L-amino acids
Pseudouridine synthase I TruA alpha/beta
Large ribosomal subunit protein uL2 C-terminal
Inosine/uridine-preferring nucleoside hydrolase
Major facilitator superfamily (MFS) profile
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Threonine/serine exporter-like N-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Penicillin-binding protein transpeptidase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Ribose-phosphate pyrophosphokinase N-terminal
Polymerase/histidinol phosphatase N-terminal
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Type VII secretion system protein EssD-like
Large ribosomal subunit protein uL6 alpha-beta
Membrane insertase YidC/Oxa/ALB C-terminal
DNA mismatch repair proteins mutS family
Gram-positive cocci surface proteins LPxTG domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Involved in allosteric activation by GTP
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
6-phosphogluconate dehydrogenase C-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Pyrroline-5-carboxylate reductase catalytic N-terminal
Phosphotransferase system enzyme I N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Gram-positive cocci surface proteins LPxTG
Small ribosomal subunit protein uS4 N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
ABC-type glycine betaine transport system substrate-binding
Pyrimidine nucleoside phosphorylase C-terminal
Cation-transporting P-type ATPase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
O-(3'-phospho-DNA)-tyrosine intermediate
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Conserved virulence factor B-like winged helix
Signal recognition particle SRP54 helical bundle
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Type III restriction enzyme C-terminal endonuclease
Glycoside hydrolase family 31 N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Phosphatidic acid phosphatase type 2/haloperoxidase
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Carbamoyl-phosphate synthase small subunit N-terminal
tRNA pseudouridylate synthase B C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Choloylglycine hydrolase/NAAA C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Polysaccharide biosynthesis protein C-terminal
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Chromosomal replication initiator DnaA C-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
ADP ribosyltransferase domain-containing protein
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Release factor glutamine methyltransferase N-terminal
Sporulation transcription regulator WhiA N-terminal
Schiff-base intermediate with acetaldehyde
Prokaryotic-type class I peptide chain release factors
Anthranilate synthase component I N-terminal
Cell envelope-related transcriptional attenuator
Tryptophan synthase beta chain-like PALP
Glycosyl transferase family 3 N-terminal
NIF system FeS cluster assembly NifU N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
YbaK/aminoacyl-tRNA synthetase-associated
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Phosphoribosylformylglycinamidine synthase linker
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
CobB/CobQ-like glutamine amidotransferase
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
SGNH hydrolase-type esterase domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase
Alpha-L-rhamnosidase six-hairpin glycosidase
Transcriptional regulator TetR C-terminal Firmicutes type
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Surface layer protein A domain-containing protein
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Thiamin pyrophosphokinase thiamin-binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Pyridoxamine 5'-phosphate oxidase putative
Plays an important role in substrate specificity
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Important for beta-aspartyl-AMP intermediate formation
Beta-xylosidase C-terminal Concanavalin A-like
FAD-dependent oxidoreductase 2 FAD binding
Septum formation inhibitor MinC C-terminal
Peptidase M1 membrane alanine aminopeptidase
Alpha-D-phosphohexomutase alpha/beta/alpha
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Important for interaction with partner proteins
Peptide methionine sulphoxide reductase MsrA
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Interaction with polymerase core subunit RpoC
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Ribosomal RNA adenine methylase transferase N-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Translation elongation factor P/YeiP central
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Sugar fermentation stimulation protein C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Reversibly protonated during proton transport
Exonuclease VII large subunit C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Alanyl-transfer RNA synthetases family profile
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Cobalamin-independent methionine synthase MetE N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Peptidase M10 metallopeptidase domain-containing protein
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Large ribosomal subunit protein uL15/eL18
DNA-directed DNA polymerase family A palm
Phosphomannose isomerase type I catalytic
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
SUF system FeS cluster assembly SufBD N-terminal