Pyruvate/ketoisovalerate oxidoreductase catalytic
Large ribosomal subunit protein uL15/eL18
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Pseudouridine synthase I TruA alpha/beta
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Small ribosomal subunit protein uS15 N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Glucose-6-phosphate isomerase prokaryote
Molybdopterin cofactor biosynthesis C (MoaC)
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
DNA mismatch repair proteins mutS family
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Transcription factor CBF/NF-Y/archaeal histone
Mannose-6-phosphate isomerase type II C-terminal
Survival protein SurE-like phosphatase/nucleotidase
Type I restriction modification DNA specificity
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr C-terminal
Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr N-terminal
Bacterial type II secretion system protein E
Large ribosomal subunit protein uL2 C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
Plays an important role in substrate specificity
rRNA small subunit methyltransferase F RNA-binding PUA-like
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Pyrimidine nucleoside phosphorylase C-terminal
RNA 3'-terminal phosphate cyclase insert
Transcription factor NikR nickel binding C-terminal
Aldehyde ferredoxin oxidoreductase N-terminal
NIF system FeS cluster assembly NifU N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Removed in mature form; by autocatalysis
Pyridoxamine 5'-phosphate oxidase putative
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Polymerase/histidinol phosphatase N-terminal
Tryptophan synthase beta chain-like PALP
Exosome complex component CSL4 C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Translation elongation factor IF5A C-terminal
Dihydroorotate dehydrogenase electron transfer subunit iron-sulphur cluster binding
Glutamate synthase alpha subunit C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Schiff-base intermediate with dihydroxyacetone-P
Methanogenesis regulatory protein FilR1 middle
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
DNA-directed RNA polymerase subunit 2 hybrid-binding
DNA-directed RNA polymerase RBP11-like dimerisation
HicB-like antitoxin of toxin-antitoxin system
Anthranilate synthase component I N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
SAM-dependent methyltransferase TRM5/TYW2-type
Major facilitator superfamily (MFS) profile
Gfo/Idh/MocA-like oxidoreductase N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Dihydroneopterin aldolase MtpD C-terminal
tRNA nucleotidyltransferase substrate binding
Type II restriction enzyme and methyltransferase RM.Eco57I-like
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
DNA polymerase II large subunit DP2 N-terminal
Glycosyl transferase family 3 N-terminal
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
CobB/CobQ-like glutamine amidotransferase
S-adenosyl-L-homocysteine hydrolase NAD binding
Serine/threonine specific protein phosphatases
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Aspartate carbamoyltransferase regulatory subunit C-terminal
Aspartate carbamoyltransferase regulatory subunit N-terminal
Proliferating cell nuclear antigen PCNA C-terminal
Proliferating cell nuclear antigen PCNA N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Ribosome maturation protein SDO1/SBDS C-terminal
Ribosome maturation protein SDO1/SBDS N-terminal
Ribosome maturation protein SDO1/SBDS central
Non-canonical purine NTP phosphatase/PRRC1
CO dehydrogenase/acetyl-CoA synthase complex beta subunit C-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
RNA 2-O ribose methyltransferase substrate binding
Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop
Prepilin type IV endopeptidase peptidase
Alanyl-transfer RNA synthetases family profile
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange
CO dehydrogenase/acetyl-CoA synthase delta subunit TIM barrel
Quinolinate phosphoribosyl transferase C-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Spo11/DNA topoisomerase VI subunit A N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Carbamoyl-phosphate synthase small subunit N-terminal
Pyruvate phosphate dikinase AMP/ATP-binding
Bacterial bifunctional deaminase-reductase C-terminal
UDP-glucose/GDP-mannose dehydrogenase N-terminal
UDP-glucose/GDP-mannose dehydrogenase dimerisation
Polysaccharide biosynthesis protein CapD-like
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cytochrome c-type biogenesis protein CcmF C-terminal
Large ribosomal subunit protein uL10-like insertion
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Cytochrome C biogenesis protein transmembrane
ATPsynthase alpha/beta subunit N-terminal extension
6-hydroxymethylpterin diphosphokinase MptE-like
Dinitrogenase iron-molybdenum cofactor biosynthesis
Glycosyltransferase subfamily 4-like N-terminal
NADH:ubiquinone oxidoreductase 30kDa subunit
Archaeal glycosylation protein B peripheral
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
F420-non-reducing hydrogenase iron-sulfur subunit D
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Transcription regulator AsnC/Lrp ligand binding
NIF system FeS cluster assembly NifU C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Water stress and hypersensitive response
Phosphoribosylformylglycinamidine synthase linker
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
Small ribosomal subunit protein uS4 N-terminal
Signal transduction histidine kinase dimerisation/phosphoacceptor
Solute-binding protein family 3/N-terminal
Damage-control phosphatase ARMT1-like metal-binding
Sodium/calcium exchanger membrane region
MPBQ/MBSQ family SAM-binding methyltransferase profile
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Thymidylate synthase/dCMP hydroxymethylase
DNA polymerase alpha/delta/epsilon subunit B