Butirosin biosynthesis protein H N-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Inosine/uridine-preferring nucleoside hydrolase
Glycosyl hydrolase-like 10 domain-containing protein
Major facilitator superfamily (MFS) profile
Penicillin-binding protein transpeptidase
Cytochrome b/b6 N-terminal region profile
Transcription factor NikR nickel binding C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Leucine-binding protein domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Tryptophan synthase beta chain-like PALP
Solute-binding protein family 5 domain-containing protein
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Schiff-base intermediate with acetaldehyde
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Phosphatidic acid phosphatase type 2/haloperoxidase
Sporulation stage IV protein A C-terminal
RNA 2-O ribose methyltransferase substrate binding
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Schiff-base intermediate with D-ribose 5-phosphate
Polysaccharide biosynthesis protein C-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Pyridine nucleotide-disulphide oxidoreductase dimerisation
ABC transporter substrate-binding protein
Glucosamine/galactosamine-6-phosphate isomerase
Could play a key role in the communication between the regulatory and the substrate sites
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Could be important to modulate the pK values of the two catalytic cysteine residues
O-(5'-phospho-DNA)-tyrosine intermediate
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Probable transposase IS891/IS1136/IS1341
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
May play a role in transmitting local conformational changes
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glycosyl transferase family 3 N-terminal
Cytochrome b/b6 C-terminal region profile
Aminoacyl-transfer RNA synthetases class-II family profile
Solute-binding protein family 3/N-terminal domain-containing protein
6-phosphogluconate dehydrogenase NADP-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Large ribosomal subunit protein bL9 C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Spermidine/putrescine ABC transporter substrate-binding protein
Interaction with polymerase core subunit RpoC
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL2 C-terminal
Phosphotransferase system enzyme I N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Large ribosomal subunit protein uL6 alpha-beta
Small ribosomal subunit protein uS4 N-terminal
Cell envelope-related transcriptional attenuator
Mannose-6-phosphate isomerase type II C-terminal
ABC transporter substrate-binding protein PnrA-like
DNA-directed DNA polymerase family A palm
Polymerase/histidinol phosphatase N-terminal
ABC-type glycine betaine transport system substrate-binding
ABC-type glycine betaine transport system substrate-binding domain-containing protein
Cation-transporting P-type ATPase N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Cysteine sulfenic acid (-SOH) intermediate
Pyrimidine nucleoside phosphorylase C-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Dipicolinate synthase subunit A N-terminal
Copper amine oxidase-like N-terminal domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Aspartate/homoserine dehydrogenase NAD-binding
Fe/B12 periplasmic-binding domain-containing protein
DNA replication/recombination mediator RecO N-terminal
Beta-hexosaminidase bacterial type N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Bacterial type II secretion system protein E
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Pyridoxamine 5'-phosphate oxidase putative
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Septum formation inhibitor MinC C-terminal
Transposase IS116/IS110/IS902 C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Peptidase M1 membrane alanine aminopeptidase
Molybdopterin cofactor biosynthesis C (MoaC)
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Flagellar assembly protein FliH/Type III secretion system HrpE
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Signal recognition particle SRP54 helical bundle
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Large ribosomal subunit protein uL15/eL18
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Flagellar motor switch protein FliN-like C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Superoxide dismutase copper/zinc binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Peptide methionine sulphoxide reductase MsrA
Phosphocysteine intermediate; for EIIB activity
Kanamycin nucleotidyltransferase C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Plays an important role in substrate specificity
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Translation elongation factor P/YeiP central
Carbamoyl-phosphate synthase small subunit N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Alpha-L-rhamnosidase six-hairpin glycosidase
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Reversibly protonated during proton transport
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Pseudouridine synthase I TruA alpha/beta
Cell wall-active antibiotics response LiaF-like C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Release factor glutamine methyltransferase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Polysaccharide chain length determinant N-terminal
Sporulation transcription regulator WhiA N-terminal
SUF system FeS cluster assembly SufBD N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Glycosyltransferase subfamily 4-like N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
tRNA pseudouridylate synthase B C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Quercetin 2,3-dioxygenase C-terminal cupin
Glycine cleavage T-protein C-terminal barrel
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Involved in allosteric activation by GTP
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
NIF system FeS cluster assembly NifU C-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Glutathionylspermidine synthase pre-ATP-grasp-like
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Fibronectin type-III domain-containing protein
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Flagellar hook-length control protein-like C-terminal
Important for beta-aspartyl-AMP intermediate formation
NADH-rubredoxin oxidoreductase C-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Type 2A encapsulin shell protein SrpI-like
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Bypass of forespore C C-terminal domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Na+-translocating membrane potential-generating system MpsC
Threonine/serine exporter-like N-terminal
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Anthranilate synthase component I N-terminal
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Tellurite resistance methyltransferase TehB-like
RNA binding; important for wobble base 34 recognition
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Na+/H+ antiporter MnhB subunit-related protein
Important for interaction with partner proteins
Gly-cisPro motif, important for rejection of L-amino acids
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Essential for prephenate dehydratase activity
Aconitase A/isopropylmalate dehydratase small subunit swivel
N6 adenine-specific DNA methyltransferase N-terminal
Glycosyltransferase family 28 N-terminal
Amino acid ABC transporter substrate-binding protein
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Phosphoribosylformylglycinamidine synthase linker
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
SsuA/THI5-like domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Single-stranded-DNA-specific exonuclease RecJ C-terminal
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Ribose-phosphate pyrophosphokinase N-terminal
Methylguanine DNA methyltransferase ribonuclease-like
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Chromosomal replication initiator DnaA C-terminal
Bacterial transcription activator effector binding
Periplasmic binding protein domain-containing protein
Transcription regulator AsnC/Lrp ligand binding
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
RND efflux pump membrane fusion protein barrel-sandwich
Alanyl-transfer RNA synthetases family profile
Sodium/calcium exchanger membrane region
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Schiff-base intermediate with substrate; via topaquinone
Bacterial alpha-L-rhamnosidase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Helix-hairpin-helix DNA-binding motif class 1
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Heme-copper oxidase subunit III family profile
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Exonuclease VII large subunit C-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Cytochrome C biogenesis protein transmembrane
YbaK/aminoacyl-tRNA synthetase-associated
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
DNA mismatch repair proteins mutS family
Inner membrane protein YgaP-like transmembrane
Integron-associated effector binding protein
S-adenosylmethionine-dependent methyltransferase
Protein-PII uridylyltransferase N-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Glycoside hydrolase family 31 N-terminal
DnaJ homologue subfamily C member 28 conserved
Sugar ABC transporter substrate-binding protein
6-phosphogluconate dehydrogenase C-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type