Outer-membrane lipoprotein carrier protein
Major facilitator superfamily (MFS) profile
TonB-dependent receptor-like beta-barrel
RNA polymerase sigma factor 70 region 4 type 2
Solute-binding protein family 3/N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Glycosyltransferase subfamily 4-like N-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Antitoxin Xre/MbcA/ParS-like toxin-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Aminoacyl-transfer RNA synthetases class-II family profile
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Tyrosine specific protein phosphatases domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
YbhB/YbcL family Raf kinase inhibitor-like protein
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Endoribonuclease L-PSP/chorismate mutase-like
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Lysozyme inhibitor LprI N-terminal domain-containing protein
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Cytochrome b561 bacterial/Ni-hydrogenase
Translocation and assembly module subunit TamA
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Carbamoyl-phosphate synthase small subunit N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Anthranilate synthase component I N-terminal
Proton acceptor; for decarboxylase activity
Proton donor; for decarboxylase activity
Proton donor; for formyltransferase activity
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
ABC-type glycine betaine transport system substrate-binding
UDP N-acetylglucosamine O-acyltransferase C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
ABC transporter substrate-binding protein PnrA-like
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Adaptive response protein AidB N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Quorum-sensing-regulated virulence factor family protein
Nitrite/Sulfite reductase ferredoxin-like
Membrane-bound lytic murein transglycosylase A
Survival protein SurE-like phosphatase/nucleotidase
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Plays an important role in substrate specificity
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
DNA-3-methyladenine glycosylase AlkA N-terminal
Glycine cleavage T-protein C-terminal barrel
Important for interaction with partner proteins
Secretin/TonB short N-terminal domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Gp5/Type VI secretion system Vgr protein OB-fold
Polysaccharide biosynthesis protein CapD-like
Heme-copper oxidase subunit III family profile
ABC-type glycine betaine transport system substrate-binding domain-containing protein
DNA-directed DNA polymerase family A palm
O-(5'-phospho-DNA)-tyrosine intermediate
Ribosomal RNA small subunit methyltransferase E methyltransferase
Alpha-glycerophosphate oxidase C-terminal
Integral membrane protein YccS N-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Interacts with tRNA; defines subfamily-specific binding signature
Branched-chain amino acid ABC transporter substrate-binding protein
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Membrane fusion protein biotin-lipoyl like
Involved in tetramerization or stability of the tetramer
Outer membrane protein assembly factor BamA
Organic solvent tolerance-like N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Bacterial transcription activator effector binding
Polyribonucleotide nucleotidyltransferase
Cation-transporting P-type ATPase N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
ABC transporter substrate-binding protein
Important for substrate binding and specificity
Pyruvate dehydrogenase E1 component middle
YbaK/aminoacyl-tRNA synthetase-associated
Chromosomal replication initiator protein DnaA
Poly-beta-hydroxybutyrate polymerase N-terminal
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
S-adenosylmethionine-dependent methyltransferase
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
RND efflux pump membrane fusion protein barrel-sandwich
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Glycoside hydrolase family 42 N-terminal
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Glucose-methanol-choline oxidoreductase N-terminal
DNA replication/recombination mediator RecO N-terminal
Translation elongation factor P/YeiP central
Carboxypeptidase regulatory-like domain-containing protein
Flagellar assembly protein FliH/Type III secretion system HrpE
Bacterial type II secretion system protein E
Essential for prephenate dehydratase activity
Biopterin-dependent aromatic amino acid hydroxylase family profile
Acyl-CoA dehydrogenase C-terminal bacterial-type
Bacterial bifunctional deaminase-reductase C-terminal
O-(phosphoribosyl dephospho-coenzyme A)serine
C-type lysozyme inhibitor domain-containing protein
Release factor glutamine methyltransferase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Tryptophan synthase beta chain-like PALP
Bacteriophage tail tape measure C-terminal
Bacteriophage tail tape measure N-terminal
Regulator of nucleoside diphosphate kinase N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Plays an important role in discriminating NADH against NADPH
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)
Glucan biosynthesis periplasmic MdoG C-terminal
Haem-binding uptake Tiki superfamily ChaN
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
PhoD-like phosphatase metallophosphatase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Glucose-methanol-choline oxidoreductase C-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Nucleoside-specific outer membrane channel protein Tsx
Mannose-6-phosphate isomerase type II C-terminal
7 transmembrane helices usually fused to an inactive transglutaminase
Inactive transglutaminase fused to 7 transmembrane helices
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Phosphoadenosine phosphosulphate reductase
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Lysidine-tRNA(Ile) synthetase C-terminal
Required for dimer formation and molybdate binding
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Polymerase/histidinol phosphatase N-terminal
Ionotropic glutamate receptor C-terminal
Divergent polysaccharide deacetylase family protein
Mandelate racemase/muconate lactonizing enzyme C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Electron transfer via tryptophanyl radical
Flagellar motor switch protein FliN-like C-terminal
Polypeptide-transport-associated ShlB-type
ShlB/FhaC/HecB family hemolysin secretion/activation protein
HicB-like antitoxin of toxin-antitoxin system
N-sulphoglucosamine sulphohydrolase C-terminal
Thymidylate synthase/dCMP hydroxymethylase
O-(3'-phospho-DNA)-tyrosine intermediate
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Quinohemoprotein amine dehydrogenase gamma subunit structural
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Flagellar hook-length control protein-like C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Glycosyl transferase family 3 N-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Type II secretion system protein GspG C-terminal
2-aminoethylphosphonate ABC transporter substrate-binding protein
Complete loss of repression of hcnA in vivo.
Partial loss of repression of hcnA in vivo, decreased affinity for mRNA.
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
4'-phosphopantetheinyl transferase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Flagella basal body P-ring formation protein FlgA
Glucosamine/galactosamine-6-phosphate isomerase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
L,D-transpeptidase catalytic domain-containing protein
Glycoside-hydrolase family GH114 TIM-barrel
Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein
6-phosphogluconate dehydrogenase C-terminal
Terminase large subunit gp17-like C-terminal
Large ribosomal subunit protein uL2 C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
NIF system FeS cluster assembly NifU C-terminal
Leucine-binding protein domain-containing protein
Phosphocysteine intermediate; for EIIB activity
Helix-hairpin-helix DNA-binding motif class 1
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Ribose-phosphate pyrophosphokinase N-terminal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
6-hydroxymethylpterin diphosphokinase MptE-like
S-adenosyl-L-homocysteine hydrolase NAD binding
Arginine decarboxylase C-terminal helical
Type II secretion system protein GspI C-terminal
Chromosomal replication initiator DnaA C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Probable periplasmic serine endoprotease DegP-like
Prepilin type IV endopeptidase peptidase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Type VI secretion system IcmF C-terminal
NIF system FeS cluster assembly NifU N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
For 3-hydroxyacyl-CoA dehydrogenase activity
Important for autoinhibition of adenylyltransferase activity
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Peptide methionine sulphoxide reductase MsrA
Ribosomal RNA small subunit methyltransferase E PUA-like
Chalcone isomerase domain-containing protein
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
Putative Flp pilus-assembly TadG-like N-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Erythronate-4-phosphate dehydrogenase dimerisation
Membrane insertase YidC/Oxa/ALB C-terminal
Putative regulatory protein FmdB Zinc ribbon
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Outer membrane assembly lipoprotein YfiO
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
N-end rule aminoacyl transferase C-terminal
High-affinity branched-chain amino acid transport system permease LivHM N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
Prokaryotic-type class I peptide chain release factors
Saccharopine dehydrogenase-like C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Interaction with polymerase core subunit RpoC
ABC-type transport auxiliary lipoprotein component
TRAP C4-dicarboxylate transport system permease DctM subunit
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Cytochrome c-type biogenesis protein CcmF C-terminal
Lipopolysaccharide export system protein LptA
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Polysaccharide biosynthesis protein C-terminal
RNA 2-O ribose methyltransferase substrate binding
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Cob(I)alamin adenosyltransferase N-terminal
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Inner membrane protein YgaP-like transmembrane
Inhibitor of vertebrate lysozyme family protein
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Positions MEP for the nucleophilic attack
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Small ribosomal subunit protein uS4 N-terminal
DNA mismatch repair proteins mutS family
Acetylserotonin O-methyltransferase dimerisation
Glutathionylspermidine synthase pre-ATP-grasp-like
NADH-rubredoxin oxidoreductase C-terminal
Cell wall hydrolase SleB domain-containing protein
Seems to be a necessary countercharge to the potassium cations
Quinoprotein dehydrogenase-associated SoxYZ-like carrier
Quercetin 2,3-dioxygenase C-terminal cupin
Aconitase A/isopropylmalate dehydratase small subunit swivel
NADH:ubiquinone oxidoreductase 30kDa subunit
NAD(P) transhydrogenase alpha subunit C-terminal
Gamma-glutamylcyclotransferase AIG2-like
Type III secretion system flagellar brake protein YcgR PilZN
DNA topoisomerase I catalytic core eukaryotic-type
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Murein L,D-transpeptidase catalytic domain family protein
Sugar fermentation stimulation protein C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Quinohemoprotein amine dehydrogenase alpha subunit
Quinohemoprotein amine dehydrogenase alpha subunit haem binding
Protein activator of alkane oxidation PraB
Large ribosomal subunit protein uL15/eL18
Phosphatidylglycerol lysyltransferase C-terminal
Bifunctional diguanylate cyclase/phosphodiesterase
Serine aminopeptidase S33 domain-containing protein
Transposase IS204/IS1001/IS1096/IS1165 DDE
DNA polymerase III subunit delta C-terminal
Molybdopterin cofactor biosynthesis C (MoaC)
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Disulphide bond isomerase DsbC/G N-terminal
Water stress and hypersensitive response
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Malonate/sodium symporter MadM subunit N-terminal
Type I restriction enzyme R protein N-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Thiol:disulfide interchange protein DsbD
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Inosine/uridine-preferring nucleoside hydrolase
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Exonuclease VII large subunit C-terminal
Proline utilization A proline dehydrogenase N-terminal
Water stress and hypersensitive response domain-containing protein
Large ribosomal subunit protein uL6 alpha-beta
Putative beta-barrel assembly-enhancing protease
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Calcium/calmodulin-dependent protein kinase II association-domain
Calcium/calmodulin-dependent protein kinase II association-domain domain-containing protein
Peptidase M61 catalytic domain-containing protein
Phospholipase/carboxylesterase/thioesterase domain-containing protein
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Outer membrane protein beta-barrel domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Reversibly protonated during proton transport
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Moves into active site upon enzyme activation, plays a role in electron transfer