Aromatic hydrocarbon degradation protein
Glycine cleavage T-protein C-terminal barrel
Bacterial bifunctional deaminase-reductase C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
PhoD-like phosphatase metallophosphatase
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Glycosyl hydrolases family 2 sugar binding domain-containing protein
Calcium-dependent phosphoinositide phospholipase C
YbgF trimerisation domain-containing protein
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Resolvase/invertase-type recombinase catalytic
Signal transduction histidine kinase subgroup 2 dimerisation and phosphoacceptor
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Electron transfer flavoprotein alpha/beta-subunit N-terminal
TonB-dependent receptor-like beta-barrel
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Glycosyl transferase family 3 N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Secretin/TonB short N-terminal domain-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Poly-beta-hydroxybutyrate polymerase N-terminal
PHA accumulation regulator DNA-binding N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Penicillin-binding protein transpeptidase
Chromosomal replication initiator protein DnaA
Anthranilate synthase component I N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
SGNH hydrolase-type esterase domain-containing protein
Superoxide dismutase copper/zinc binding
Superoxide dismutase copper/zinc binding domain-containing protein
AB hydrolase-1 domain-containing protein
2-oxoisovalerate dehydrogenase E1 alpha subunit N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
Outer membrane protein beta-barrel domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
FAD-dependent oxidoreductase 2 FAD binding
RND efflux pump membrane fusion protein barrel-sandwich
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Major facilitator superfamily (MFS) profile
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Alpha galactosidase C-terminal beta sandwich
Methylguanine DNA methyltransferase ribonuclease-like
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
DNA translocase FtsK 4TM region domain-containing protein
Cytochrome b561 bacterial/Ni-hydrogenase
Right handed beta helix domain-containing protein
Peptidase M20 dimerisation domain-containing protein
Anti-bacteriophage protein A/HamA C-terminal
General stress protein FMN-binding split barrel
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Alpha/beta hydrolase fold-3 domain-containing protein
Terminase large subunit-like endonuclease
Glycoside hydrolase family 31 N-terminal
Interaction with polymerase core subunit RpoC
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Isochorismatase-like domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Helix-hairpin-helix DNA-binding motif class 1
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Twin-arginine translocation pathway signal protein
RNA polymerase sigma factor 70 region 4 type 2
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Transposase IS116/IS110/IS902 C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Protein O-mannosyl-transferase C-terminal four TM
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Glucosamine/galactosamine-6-phosphate isomerase
Heme-copper oxidase subunit III family profile
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
DNA topoisomerase I catalytic core eukaryotic-type
Peptidase M1 membrane alanine aminopeptidase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Polymerase/histidinol phosphatase N-terminal
Type II secretion system protein GspI C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Peptidase M14 carboxypeptidase A domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Peptide methionine sulphoxide reductase MsrA
Pyrimidine nucleoside phosphorylase C-terminal
Essential for prephenate dehydratase activity
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Beta/gamma crystallin 'Greek key' domain-containing protein
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Amidohydrolase-related domain-containing protein
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Phosphoribosylformylglycinamidine synthase linker
Cytochrome c-type biogenesis protein CcmF C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Cob(I)alamin adenosyltransferase N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
6-phosphogluconate dehydrogenase C-terminal
Light-independent protochlorophyllide reductase subunit B-like C-terminal
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Tryptophan synthase beta chain-like PALP
Disulphide bond isomerase DsbC/G N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Prokaryotic-type class I peptide chain release factors
Alginate export domain-containing protein
Autotransporter domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Glycosyl hydrolase family 95 N-terminal domain-containing protein
Magnesium-protoporphyrin IX methyltransferase C-terminal
Schiff-base intermediate with dihydroxyacetone-P
Activator of Hsp90 ATPase homologue 1-like C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Amidohydrolase 3 domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Pectate lyase superfamily protein domain-containing protein
RNA 3'-terminal phosphate cyclase insert
Cytochrome P460 domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Cysteine sulfenic acid (-SOH) intermediate
Phosphogluconate dehydrogenase NAD-binding putative C-terminal
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
Antitoxin Xre/MbcA/ParS-like toxin-binding
tRNA pseudouridylate synthase B C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Thioredoxin-like fold domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Proton acceptor; for glutaminase activity
TonB-dependent receptor-like beta-barrel domain-containing protein
Aminotransferase class V domain-containing protein
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Molybdenum ABC transporter substrate-binding protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein
Nitrite/Sulfite reductase ferredoxin-like
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Beta-lactamase-related domain-containing protein
Metallo-beta-lactamase domain-containing protein
Type VII secretion system protein EssD-like
Translation elongation factor P/YeiP central
Release factor glutamine methyltransferase N-terminal
Xylose isomerase-like TIM barrel domain-containing protein
NIF system FeS cluster assembly NifU N-terminal
Phosphoadenosine phosphosulphate reductase
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Sialate O-acetylesterase domain-containing protein
Cell wall hydrolase SleB domain-containing protein
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Glycoside hydrolase GH146 substrate-binding
Glycoside hydrolase GH146 substrate-binding domain-containing protein
ATP synthase F1 complex delta/epsilon subunit N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Type II secretion system protein GspC N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Aspartate/homoserine dehydrogenase NAD-binding
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Heat-inducible transcription repressor HrcA C-terminal
Lactate utilization protein B C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Phosphodiester glycosidase domain-containing protein
Moves into active site upon enzyme activation, plays a role in electron transfer
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Endoribonuclease L-PSP/chorismate mutase-like
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Tip attachment protein J domain-containing protein
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Molybdopterin cofactor biosynthesis C (MoaC)
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Histidine kinase/HSP90-like ATPase domain-containing protein
cyclic-guanylate-specific phosphodiesterase
Type IV secretion system coupling protein TraD DNA-binding
SUF system FeS cluster assembly SufBD N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
HTH-type transcriptional regulator MT1864/Rv1816-like C-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
RNA 2-O ribose methyltransferase substrate binding
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Photosynthetic reaction centre H subunit N-terminal
Signal transduction histidine kinase HWE region
Small ribosomal subunit protein uS4 N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Lipoprotein SmpA/OmlA domain-containing protein
CDP-alcohol phosphatidyltransferase C-terminal
ABC transporter substrate-binding protein
Sodium/calcium exchanger membrane region
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Histidine-specific methyltransferase SAM-dependent
Prolyl 3,4-dihydroxylase TPA1/OFD1 N-terminal
Glutamate synthase alpha subunit C-terminal
Outer membrane protein assembly factor BamD
Flagellar motor switch protein FliN-like C-terminal
Trimeric autotransporter adhesin YadA-like head
Trimeric autotransporter adhesin YadA-like head domain-containing protein
Histidine phosphotransferase ChpT C-terminal
Membrane fusion protein biotin-lipoyl like
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Flagellar basal body rod protein N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Methionyl-tRNA synthetase anticodon-binding
Transglycosylase SLT domain-containing protein
Sulfatase N-terminal domain-containing protein
Flagellar basal-body/hook protein C-terminal
YbaK/aminoacyl-tRNA synthetase-associated
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Quinohemoprotein amine dehydrogenase gamma subunit structural
Probable periplasmic serine endoprotease DegP-like
Large ribosomal subunit protein uL15/eL18
DNA replication/recombination mediator RecO N-terminal
RNA binding; important for wobble base 34 recognition
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Exonuclease VII large subunit C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Polysaccharide chain length determinant N-terminal
3-keto-disaccharide hydrolase domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Phosphatidic acid phosphatase type 2/haloperoxidase
Solute-binding protein family 5 domain-containing protein
Arabinogalactan endo-beta-1,4-galactanase
Could be important to modulate the pK values of the two catalytic cysteine residues
Quercetin 2,3-dioxygenase C-terminal cupin
Sulfatase-modifying factor enzyme domain-containing protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Nucleophile; cysteine thiosulfonate intermediate
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cellulose synthase operon C C-terminal domain-containing protein
NAD(P) transhydrogenase alpha subunit C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Cation-transporting P-type ATPase N-terminal
Tyrosine specific protein phosphatases domain-containing protein
Signal recognition particle SRP54 helical bundle
NlpE C-terminal OB domain-containing protein
Methylamine/Aralkylamine dehydrogenase light chain C-terminal
Tryptophylquinone 6'-substrate hemiaminal intermediate
Alanyl-transfer RNA synthetases family profile
Beta-lactamase hydrolase-like protein phosphatase-like
S-adenosyl-L-homocysteine hydrolase NAD binding
Peptidase S33 tripeptidyl aminopeptidase-like C-terminal
OmpR/PhoB-type domain-containing protein
Alpha-L-rhamnosidase six-hairpin glycosidase
Bacterial alpha-L-rhamnosidase N-terminal
Plays an important role in substrate specificity
Peptidase M16 C-terminal domain-containing protein
O-(5'-phospho-DNA)-tyrosine intermediate
Cytochrome c oxidase subunit IV bacterial aa3 type
Beta propeller domain-containing protein