TRAP C4-dicarboxylate transport system permease DctM subunit
Alanyl-transfer RNA synthetases family profile
Tryptophan synthase beta chain-like PALP
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Aminoacyl-transfer RNA synthetases class-II family profile
Solute-binding protein family 3/N-terminal
ABC-type glycine betaine transport system substrate-binding
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Acetyl-CoA dehydrogenase-like C-terminal
Acyl-CoA dehydrogenase N-terminal bacteria
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
3-beta hydroxysteroid dehydrogenase/isomerase
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Mandelate racemase/muconate lactonizing enzyme C-terminal
Glucose-methanol-choline oxidoreductase C-terminal
S-adenosyl-L-homocysteine hydrolase NAD binding
ATP synthase F1 complex delta/epsilon subunit N-terminal
Reversibly protonated during proton transport
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Plasmid replication protein C C-terminal
Plasmid replication protein C N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Cytochrome c-type biogenesis protein CcmF C-terminal
L,D-transpeptidase catalytic domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Major facilitator superfamily (MFS) profile
Bacterial bifunctional deaminase-reductase C-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
NAD(P) transhydrogenase alpha subunit C-terminal
Translation elongation factor P/YeiP central
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Anthranilate synthase component I N-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Styrene monooxygenase StyA putative substrate binding
Membrane fusion protein biotin-lipoyl like
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Ionotropic glutamate receptor C-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Thiol:disulfide interchange protein DsbD N-terminal
Thiol:disulfide interchange protein DsbD N-terminal domain-containing protein
Sodium/calcium exchanger membrane region
Pyridoxamine 5'-phosphate oxidase putative
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Heme-copper oxidase subunit III family profile
Peptide methionine sulphoxide reductase MsrA
Microcystin LR degradation protein MlrC C-terminal
Microcystin LR degradation protein MlrC N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Type II secretion system protein GspE N-terminal
Interaction with polymerase core subunit RpoC
Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Endoribonuclease L-PSP/chorismate mutase-like
Cytochrome b561 bacterial/Ni-hydrogenase
Glucosamine/galactosamine-6-phosphate isomerase
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Glycine cleavage T-protein C-terminal barrel
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Transcription regulator AsnC/Lrp ligand binding
Pyrimidine nucleoside phosphorylase C-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Transposase IS116/IS110/IS902 C-terminal
N-sulphoglucosamine sulphohydrolase C-terminal
Pyruvate dehydrogenase E1 component middle
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
S-adenosylmethionine-dependent methyltransferase
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Saccharopine dehydrogenase-like C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Putative regulatory protein FmdB Zinc ribbon
Aromatic amino acid beta-eliminating lyase/threonine aldolase
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Small ribosomal subunit protein uS4 N-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Pyruvate phosphate dikinase AMP/ATP-binding
Sugar fermentation stimulation protein C-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Methylguanine DNA methyltransferase ribonuclease-like
ABC transporter substrate-binding protein PnrA-like
Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP
Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi
Tat pathway signal sequence domain protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Nitrite/Sulfite reductase ferredoxin-like
Exonuclease VII large subunit C-terminal
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Tip attachment protein J domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Mannose-6-phosphate isomerase type II C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Superoxide dismutase copper/zinc binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
DNA replication/recombination mediator RecO N-terminal
Bacterial type II secretion system protein E
RNA binding; important for wobble base 34 recognition
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Gamma-butyrobetaine hydroxylase-like N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Pseudouridine synthase I TruA alpha/beta
Bacteriophage N4 adsorption protein A C-terminal
DNA mismatch repair proteins mutS family
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
Cytochrome c oxidase subunit IV bacterial aa3 type
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Phosphogluconate dehydrogenase (decarboxylating) C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Proline utilization A proline dehydrogenase N-terminal
Electron transfer via tryptophanyl radical
Helix-hairpin-helix DNA-binding motif class 1
Tetrahydrodipicolinate-N-succinyltransferase chain A
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Phosphoribosylformylglycinamidine synthase linker
YbaK/aminoacyl-tRNA synthetase-associated
Thymidylate synthase/dCMP hydroxymethylase
Large ribosomal subunit protein uL2 C-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Prokaryotic-type class I peptide chain release factors
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
PHA accumulation regulator DNA-binding N-terminal
NIF system FeS cluster assembly NifU N-terminal
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Type IV secretion system coupling protein TraD DNA-binding
Polymerase/histidinol phosphatase N-terminal
Cation-transporting P-type ATPase N-terminal
Cobaltochelatase subunit CobS N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Signal transduction histidine kinase internal region
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Mandelate racemase/muconate lactonizing enzyme N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Ribosomal RNA adenine methylase transferase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Glycosyltransferase subfamily 4-like N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Thiamin pyrophosphokinase thiamin-binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Cysteine sulfenic acid (-SOH) intermediate
6-phosphogluconate dehydrogenase C-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Beta-lactamase hydrolase-like protein phosphatase-like
Probable periplasmic serine endoprotease DegP-like
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Aconitase A/isopropylmalate dehydratase small subunit swivel
Important for interaction with partner proteins
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Large ribosomal subunit protein uL6 alpha-beta
Transcriptional regulator AbiEi antitoxin N-terminal
TonB-dependent receptor-like beta-barrel
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Resolvase/invertase-type recombinase catalytic
Alpha-glycerophosphate oxidase C-terminal
Inner membrane protein YgaP-like transmembrane
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Cytochrome C biogenesis protein transmembrane
UDP-glucose/GDP-mannose dehydrogenase C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
Quercetin 2,3-dioxygenase C-terminal cupin
Phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease 2
von Hippel-Lindau disease tumour suppressor beta
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Lysozyme inhibitor LprI N-terminal domain-containing protein
Transglycosylase SLT domain-containing protein
Vanillate O-demethylase oxygenase-like C-terminal catalytic
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Na+/H+ antiporter MnhB subunit-related protein
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Anaphase-promoting complex subunit 4-like WD40
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Molybdopterin cofactor biosynthesis C (MoaC)
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Glycoside hydrolase family 42 N-terminal
RNA 2-O ribose methyltransferase substrate binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Bacteriophage tail tape measure N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
D-galactarate/Altronate dehydratase C-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
CDP-alcohol phosphatidyltransferase C-terminal
Proton acceptor; for glutaminase activity
Membrane insertase YidC/Oxa/ALB C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
General stress protein FMN-binding split barrel
Choloylglycine hydrolase/NAAA C-terminal
Glycosyl transferase family 3 N-terminal
Outer membrane protein beta-barrel domain-containing protein
Required for zinc-mediated homotetramerization and catalytic activity
Ribose-phosphate pyrophosphokinase N-terminal
NADH-rubredoxin oxidoreductase C-terminal
Penicillin-binding protein transpeptidase
Plays an important role in substrate specificity
Transcription factor NikR nickel binding C-terminal
Outer membrane protein assembly factor BamA
N-end rule aminoacyl transferase C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Could play a key role in the communication between the regulatory and the substrate sites
Pyrroline-5-carboxylate reductase dimerisation
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Terminase large subunit-like endonuclease
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
O-(3'-phospho-DNA)-tyrosine intermediate
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Guanylate kinase/L-type calcium channel beta subunit
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Inosine/uridine-preferring nucleoside hydrolase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Shikimate dehydrogenase substrate binding N-terminal
Essential for prephenate dehydratase activity
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
SUF system FeS cluster assembly SufBD N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
5-glutamyl coenzyme A thioester intermediate
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Transferrin-binding protein B C-lobe/N-lobe beta barrel domain-containing protein
Glucan biosynthesis periplasmic MdoG C-terminal
Protein-methionine-sulfoxide reductase catalytic subunit MsrP
Heparan-alpha-glucosaminide N-acetyltransferase catalytic
N6 adenine-specific DNA methyltransferase N-terminal
Large ribosomal subunit protein uL15/eL18
Transferrin-binding protein B C-lobe/N-lobe beta barrel
UDP N-acetylglucosamine O-acyltransferase C-terminal
Protein involved in meta-pathway of phenol degradation
Histidine phosphotransferase ChpT C-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal