Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Resolvase/invertase-type recombinase catalytic
Membrane insertase YidC/Oxa/ALB C-terminal
Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)
Phosphoadenosine phosphosulphate reductase
Major facilitator superfamily (MFS) profile
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Lipocalin/cytosolic fatty-acid binding domain-containing protein
Helix-hairpin-helix DNA-binding motif class 1
Sporulation transcription regulator WhiA N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Aminoacyl-transfer RNA synthetases class-II family profile
Schiff-base intermediate with substrate; via pyruvic acid
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Ribosomal RNA adenine methylase transferase N-terminal
Plays an important role in substrate specificity
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
Glycosyltransferase subfamily 4-like N-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Type I restriction enzyme R protein N-terminal
Fe/B12 periplasmic-binding domain-containing protein
ABC-type glycine betaine transport system substrate-binding domain-containing protein
Translation elongation factor P/YeiP central
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Schiff-base intermediate with D-ribose 5-phosphate
Could play a key role in the communication between the regulatory and the substrate sites
L,D-transpeptidase catalytic domain-containing protein
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Tryptophan synthase beta chain-like PALP
Periplasmic binding protein domain-containing protein
ABC transporter substrate-binding protein
Cytochrome b/b6 N-terminal region profile
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Phosphatidic acid phosphatase type 2/haloperoxidase
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Putative oxidoreductase/dehydrogenase Rossmann-like
RNA binding; important for wobble base 34 recognition
Large ribosomal subunit protein uL6 alpha-beta
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
NIF system FeS cluster assembly NifU N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Type III restriction enzyme C-terminal endonuclease
Mycothiol-dependent maleylpyruvate isomerase metal-binding
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
S-adenosyl-L-homocysteine hydrolase NAD binding
Peptidase S9 prolyl oligopeptidase catalytic
Bacterial transcription activator effector binding
ABC-type glycine betaine transport system substrate-binding
Prepilin type IV endopeptidase peptidase
Bacterial bifunctional deaminase-reductase C-terminal
Alanyl-transfer RNA synthetases family profile
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Solute-binding protein family 5 domain-containing protein
Anthranilate synthase component I N-terminal
Excalibur calcium-binding domain-containing protein
Penicillin-binding protein transpeptidase
YbaK/aminoacyl-tRNA synthetase-associated
Important for substrate specificity; cannot use PPi as phosphoryl donor
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Prokaryotic-type class I peptide chain release factors
Peptide methionine sulphoxide reductase MsrA
Reversibly protonated during proton transport
Solute-binding protein family 3/N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Mandelate racemase/muconate lactonizing enzyme C-terminal
DNA-directed DNA polymerase family A palm
RNA 2-O ribose methyltransferase substrate binding
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Phosphoribosylformylglycinamidine synthase linker
Glucosamine/galactosamine-6-phosphate isomerase
SUF system FeS cluster assembly SufBD N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Gram-positive cocci surface proteins LPxTG
Arabinofuranosyltransferase AftA C-terminal
Arabinofuranosyltransferase AftA N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Positions MEP for the nucleophilic attack
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Chromosomal replication initiator DnaA C-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
AraC-type arabinose-binding/dimerisation
Phosphomannose isomerase type I catalytic
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Heat-inducible transcription repressor HrcA C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
4'-phosphopantetheinyl transferase N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Cysteine sulfenic acid (-SOH) intermediate
Important for beta-aspartyl-AMP intermediate formation
Cell envelope-related transcriptional attenuator
Nucleophile; cysteine thiosulfonate intermediate
Gly-cisPro motif, important for rejection of L-amino acids
Thymidylate synthase/dCMP hydroxymethylase
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RNA polymerase sigma factor 70 region 4 type 2
Aminoacyl-tRNA synthetase class I anticodon-binding
Inosine/uridine-preferring nucleoside hydrolase
Pyrroline-5-carboxylate reductase dimerisation
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Interaction with polymerase core subunit RpoC
Schiff-base intermediate with acetaldehyde
Phosphocysteine intermediate; for EIIB activity
Large ribosomal subunit protein uL2 C-terminal
Protocatechuate 3,4-dioxygenase beta subunit N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Resuscitation-promoting factor Rpf1 C-terminal
Resuscitation-promoting factor core lysozyme-like
Cytochrome b561 bacterial/Ni-hydrogenase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Cytochrome C biogenesis protein transmembrane
6-phosphogluconate dehydrogenase C-terminal
Polysaccharide biosynthesis protein CapD-like
Glycosyl transferase family 28 C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Essential for prephenate dehydratase activity
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Nitrite/Sulfite reductase ferredoxin-like
Aconitase A/isopropylmalate dehydratase small subunit swivel
Ribose-phosphate pyrophosphokinase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Cobalamin-independent methionine synthase MetE N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Involved in ionization of N3 of dUMP, leading to its activation
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Peptidase M1 membrane alanine aminopeptidase
Glycosyltransferase family 28 N-terminal
Glycosyl transferase family 3 N-terminal
Release factor glutamine methyltransferase N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Polysaccharide chain length determinant N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Polymerase/histidinol phosphatase N-terminal
Bacterial type II secretion system protein E
Myo-inositol-1-phosphate synthase GAPDH-like
Phosphatidate phosphatase APP1 catalytic
Pyruvate dehydrogenase E1 component middle
PhoD-like phosphatase metallophosphatase
Cell wall-active antibiotics response LiaF-like C-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Methylguanine DNA methyltransferase ribonuclease-like
Methionyl-tRNA synthetase anticodon-binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein uL15/eL18
CobB/CobQ-like glutamine amidotransferase
Large ribosomal subunit protein uL30-like ferredoxin-like fold