Acyl-CoA dehydrogenase/oxidase N-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Ribonucleotide reductase large subunit C-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Carbamoyl-phosphate synthase small subunit N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Resolvase/invertase-type recombinase catalytic
Cytochrome b/b6 N-terminal region profile
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Could play a key role in the communication between the regulatory and the substrate sites
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Cysteine sulfenic acid (-SOH) intermediate
O-(5'-phospho-DNA)-tyrosine intermediate
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Prepilin type IV endopeptidase peptidase
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Aminoacyl-transfer RNA synthetases class-II family profile
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Prokaryotic-type class I peptide chain release factors
Major facilitator superfamily (MFS) profile
Tryptophan synthase beta chain-like PALP
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
Menaquinone biosynthesis protein MenD middle
O-(3'-phospho-DNA)-tyrosine intermediate
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Phage terminase large subunit C-terminal
Phage terminase large subunit N-terminal
Flagellar motor switch protein FliN-like C-terminal
Aspartate/homoserine dehydrogenase NAD-binding
RND efflux pump membrane fusion protein barrel-sandwich
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Single-stranded-DNA-specific exonuclease RecJ C-terminal
Penicillin-binding protein transpeptidase
Phosphatidic acid phosphatase type 2/haloperoxidase
Glycine cleavage T-protein C-terminal barrel
Urease accessory protein UreH-like transmembrane
Alpha-D-phosphohexomutase alpha/beta/alpha
Phosphocysteine intermediate; for EIIB activity
Peptidase S9 prolyl oligopeptidase catalytic
Flagellar assembly protein FliH/Type III secretion system HrpE
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Sodium/calcium exchanger membrane region
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Important for beta-aspartyl-AMP intermediate formation
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Cytochrome C biogenesis protein transmembrane
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Moves into active site upon enzyme activation, plays a role in electron transfer
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Peptide methionine sulphoxide reductase MsrA
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Polysaccharide biosynthesis protein C-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Large ribosomal subunit protein uL6 alpha-beta
Cell envelope-related transcriptional attenuator
Polymerase/histidinol phosphatase N-terminal
Solute-binding protein family 3/N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
ABC transporter substrate-binding protein PnrA-like
Large ribosomal subunit protein uL2 C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
RNA binding; important for wobble base 34 recognition
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Cytochrome b/b6 C-terminal region profile
Bacterial type II secretion system protein E
CRISPR-associated protein Cas6 C-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Phosphoribosylformylglycinamidine synthase linker
Flagellar hook-length control protein-like C-terminal
Global transcriptional regulator CodY C-terminal
Global transcriptional regulator CodY N-terminal
Cation-transporting P-type ATPase N-terminal
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Chromosomal replication initiator DnaA C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Translation elongation factor P/YeiP central
Alanyl-transfer RNA synthetases family profile
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Plays an important role in substrate specificity
Phosphotransferase system enzyme I N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
6-phosphogluconate dehydrogenase C-terminal
Gly-cisPro motif, important for rejection of L-amino acids
SUF system FeS cluster assembly SufBD N-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Pseudouridine synthase I TruA alpha/beta
Phosphomannose isomerase type I catalytic
Peptidase M17 leucyl aminopeptidase N-terminal
RNA 2-O ribose methyltransferase substrate binding
Schiff-base intermediate with acetaldehyde
Restriction system protein Mrr-like N-terminal
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Heat-inducible transcription repressor HrcA C-terminal
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Polysaccharide chain length determinant N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Exonuclease VII large subunit C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Type I restriction modification DNA specificity
Inner membrane protein YgaP-like transmembrane
ATP synthase F1 complex delta/epsilon subunit N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Important for interaction with partner proteins
Involved in allosteric activation by GTP
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Glycosyltransferase subfamily 4-like N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Release factor glutamine methyltransferase N-terminal
Heme-copper oxidase subunit III family profile
Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Large ribosomal subunit protein uL15/eL18
Nitrite/Sulfite reductase ferredoxin-like
Shikimate dehydrogenase substrate binding N-terminal
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Ionotropic glutamate receptor C-terminal
Essential for prephenate dehydratase activity
Sporulation stage IV protein A C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
ABC-type glycine betaine transport system substrate-binding
tRNA pseudouridylate synthase B C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Interaction with polymerase core subunit RpoC
Pyruvate phosphate dikinase AMP/ATP-binding
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Could be important to modulate the pK values of the two catalytic cysteine residues
Type III secretion system flagellar brake protein YcgR PilZN
Thiamin pyrophosphokinase thiamin-binding
NIF system FeS cluster assembly NifU C-terminal
Saccharopine dehydrogenase-like C-terminal
DNA mismatch repair proteins mutS family
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Tryptophan RNA-binding attenuator protein
Type III restriction enzyme C-terminal endonuclease
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase N-terminal
Conserved hypothetical protein CHP02679 N terminus
Glycoside hydrolase family 42 N-terminal
Schiff-base intermediate with D-ribose 5-phosphate
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Hydroxymethylglutaryl-coenzyme A synthase C-terminal
Hydroxymethylglutaryl-coenzyme A synthase N-terminal
Anthranilate synthase component I N-terminal
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA replication/recombination mediator RecO N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Diacylglycerol glucosyltransferase N-terminal
Alpha-glycerophosphate oxidase C-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Positions MEP for the nucleophilic attack
Lysidine-tRNA(Ile) synthetase C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NIF system FeS cluster assembly NifU N-terminal
Magnesium transporter MgtE intracellular
Schiff-base intermediate with substrate; via pyruvic acid
Small ribosomal subunit protein uS4 N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Sporulation transcription regulator WhiA N-terminal
Glycosyl transferase family 3 N-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Lactate utilization protein B C-terminal