DNA/pantothenate metabolism flavoprotein C-terminal
Cob(I)alamin adenosyltransferase N-terminal
Probable transposase IS891/IS1136/IS1341
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Organic solvent tolerance-like N-terminal
Ionotropic glutamate receptor C-terminal
Solute-binding protein family 3/N-terminal
Electron transfer via tryptophanyl radical
Peptidase S9 prolyl oligopeptidase catalytic
Peptidase M1 membrane alanine aminopeptidase
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Shikimate dehydrogenase substrate binding N-terminal
Pyridoxamine 5'-phosphate oxidase putative
HicB-like antitoxin of toxin-antitoxin system
Curlin associated repeat-containing protein
Aminoacyl-transfer RNA synthetases class-II family profile
Glycosyltransferase subfamily 4-like N-terminal
Positions MEP for the nucleophilic attack
Anaphase-promoting complex subunit 4-like WD40
Photosystem I reaction center subunit III
Acyl-CoA dehydrogenase/oxidase N-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Type II secretion system protein GspE N-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
Polysaccharide biosynthesis protein C-terminal
Penicillin-binding protein transpeptidase
Schiff-base intermediate with acetaldehyde
TonB-dependent receptor-like beta-barrel
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
RNA 2-O ribose methyltransferase substrate binding
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Homogentisate 1,2-dioxygenase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Resolvase/invertase-type recombinase catalytic
Ribosomal RNA adenine methylase transferase N-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Pseudouridine synthase I TruA alpha/beta
Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
1,4-alpha-glucan branching enzyme C-terminal
Glycoside hydrolase family 57 N-terminal
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Large ribosomal subunit protein uL2 C-terminal
Inosine/uridine-preferring nucleoside hydrolase
CobB/CobQ-like glutamine amidotransferase
Increases nucleophilicity of active site Cys
Pyruvate phosphate dikinase AMP/ATP-binding
S-adenosyl-L-homocysteine hydrolase NAD binding
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Glycine-zipper-containing OmpA-like membrane
Peptide methionine sulphoxide reductase MsrA
Light-independent protochlorophyllide reductase subunit B-like C-terminal
ssDNA thymidine ADP-ribosyltransferase DarT
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Bacterial type II secretion system protein E
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Gamma-glutamylcyclotransferase AIG2-like
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Na+-translocating membrane potential-generating system MpsC
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Histidine-specific methyltransferase SAM-dependent
DNA replication/recombination mediator RecO N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase
Involved in tetramerization or stability of the tetramer
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Magnesium-protoporphyrin IX methyltransferase C-terminal
Styrene monooxygenase StyA putative substrate binding
RNA-binding protein Tab2-like N-terminal
RNA-binding protein Tab2/Atab2 C-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Carboxypeptidase regulatory-like domain-containing protein
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Chromosomal replication initiator DnaA C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding
Ribulose bisphosphate carboxylase large subunit C-terminal
Ribulose bisphosphate carboxylase large subunit ferrodoxin-like N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Methionyl-tRNA synthetase anticodon-binding
EfeO-type cupredoxin-like domain-containing protein
Ribulose bisphosphate carboxylase small subunit
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
TRAP C4-dicarboxylate transport system permease DctM subunit
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Haem-binding uptake Tiki superfamily ChaN
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Cation-transporting P-type ATPase N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Essential for prephenate dehydratase activity
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone/plastoquinone oxidoreductase chloroplast chain 5 C-terminal
May play a role in transmitting local conformational changes
Zn-dependent hydrolase of the beta-lactamase fold-like protein
Membrane insertase YidC/Oxa/ALB C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
Polysaccharide chain length determinant N-terminal
Sugar fermentation stimulation protein C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
Nicotinate phosphoribosyltransferase C-terminal
Nicotinate phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
SUF system FeS cluster assembly SufBD N-terminal
Phosphoribosylformylglycinamidine synthase linker
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Phosphonate ABC transporter, periplasmic phosphonate-binding protein
Arginine decarboxylase C-terminal helical
Release factor glutamine methyltransferase N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Plastid lipid-associated protein/fibrillin conserved
Photosystem II manganese-stabilizing polypeptide
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Tryptophan synthase beta chain-like PALP
Phage terminase large subunit GpA ATPase
Terminase large subunit GpA endonuclease
RNA binding; important for wobble base 34 recognition
Major facilitator superfamily (MFS) profile
Right handed beta helix domain-containing protein
S-adenosyl-l-methionine hydroxide adenosyltransferase C-terminal
S-adenosyl-l-methionine hydroxide adenosyltransferase N-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Glycine cleavage T-protein C-terminal barrel
Na+/H+ antiporter MnhB subunit-related protein
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Heme-copper oxidase subunit III family profile
ATP synthase F1 complex delta/epsilon subunit N-terminal
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Ferredoxin thioredoxin reductase alpha chain
Cytochrome b/b6 N-terminal region profile
Glycoside hydrolase family 5 domain-containing protein
Could play a key role in the communication between the regulatory and the substrate sites
Increases the nucleophilicity of the active site Cys
Putative glycogen debranching enzyme N-terminal
Membrane fusion protein biotin-lipoyl like
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Replication initiation protein-like C-terminal
Involved in allosteric activation by GTP
NIF system FeS cluster assembly NifU C-terminal
Photosystem II cytochrome b559 N-terminal
Photosystem II cytochrome b559 alpha subunit lumenal region
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Nucleic acid binding OB-fold tRNA/helicase-type
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Dinitrogenase iron-molybdenum cofactor biosynthesis
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Sporulation stage II protein D amidase enhancer LytB N-terminal
Filamentous hemagglutinin outer membrane protein
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycosyl transferase family 3 N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Phosphatidic acid phosphatase type 2/haloperoxidase
Mannose-6-phosphate isomerase type II C-terminal
Helix-hairpin-helix DNA-binding motif class 1
Alanyl-transfer RNA synthetases family profile
Homocysteine biosynthesis enzyme sulfur-incorporation
Protein-arginine deiminase (PAD) central
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Sodium/calcium exchanger membrane region
RNA polymerase sigma factor 70 region 4 type 2
Magnesium chelatase subunit H N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Schiff-base intermediate with substrate; via pyruvic acid
Nitrite/Sulfite reductase ferredoxin-like
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Important for substrate specificity; cannot use PPi as phosphoryl donor
O-(5'-phospho-DNA)-tyrosine intermediate
Prepilin type IV endopeptidase peptidase
2-oxoacid dehydrogenase acyltransferase catalytic
Survival protein SurE-like phosphatase/nucleotidase
RNA methyltransferase SpoU/TrmH type C-terminal
Signal transduction histidine kinase osmosensitive K+ channel sensor N-terminal
Alpha-glycerophosphate oxidase C-terminal
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Cytochrome C biogenesis protein transmembrane
Reversibly protonated during proton transport
Cyanobacterial aminoacyl-tRNA synthetase CAAD
Inward rectifier potassium channel C-terminal
Glycogen debranching enzyme bacterial and archaeal type N-terminal
Cytochrome b/b6 C-terminal region profile
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Type IV secretion system coupling protein TraD DNA-binding
Molybdopterin cofactor biosynthesis C (MoaC)
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Bacterial Glycosyl hydrolase family 3 C-terminal
Menaquinone biosynthesis protein MenD middle
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Cysteine sulfenic acid (-SOH) intermediate
Large ribosomal subunit protein uL15/eL18
Cell envelope-related transcriptional attenuator
NAD(P)H-quinone oxidoreductase subunit 2 N-terminal
Interaction with polymerase core subunit RpoC
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Small ribosomal subunit protein uS4 N-terminal
ABC-type uncharacterised transport system
DNA mismatch repair proteins mutS family
Outer membrane protein beta-barrel domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
DNA-directed DNA polymerase family A palm
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Lantibiotic biosynthesis protein dehydration
Plays an important role in substrate specificity
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Heat-inducible transcription repressor HrcA C-terminal
Glycosyl-hydrolase family 116 N-terminal
Glycosyl-hydrolase family 116 catalytic region
Urease accessory protein UreH-like transmembrane
Anthranilate synthase component I N-terminal
Phosphoadenosine phosphosulphate reductase
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Translation elongation factor P/YeiP central
Photosystem I PsaL reaction centre subunit XI
Rubisco accumulation factor 1 C-terminal
Rubisco accumulation factor 1 alpha helical
Rubisco accumulation factor 1 helix turn helix
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Polymerase/histidinol phosphatase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Proton acceptor; for glutaminase activity
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Polypeptide-transport-associated ShlB-type
6-phosphogluconate dehydrogenase C-terminal
Prokaryotic-type class I peptide chain release factors
Glucose-methanol-choline oxidoreductase C-terminal
Glucose-methanol-choline oxidoreductase N-terminal
CRISPR-associated protein Cas6 C-terminal
Quercetin 2,3-dioxygenase C-terminal cupin
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Glucosamine/galactosamine-6-phosphate isomerase