FAD-dependent cmnm(5)s(2)U34 oxidoreductase
NIF system FeS cluster assembly NifU N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
Arginine decarboxylase C-terminal helical
Involved in allosteric activation by GTP
Butirosin biosynthesis protein H N-terminal
Glycosyltransferase subfamily 4-like N-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Solute-binding protein family 3/N-terminal
Solute-binding protein family 3/N-terminal domain-containing protein
DNA mismatch repair proteins mutS family
Type II secretion system protein GspG C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Major facilitator superfamily (MFS) profile
Reversibly protonated during proton transport
Release factor glutamine methyltransferase N-terminal
Heme-copper oxidase subunit III family profile
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Membrane fusion protein biotin-lipoyl like
Peptidase S9 prolyl oligopeptidase catalytic
Aconitase A/isopropylmalate dehydratase small subunit swivel
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Inner membrane protein YgaP-like transmembrane
Flagellar assembly protein FliH/Type III secretion system HrpE
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Flagellar Assembly Protein A N-terminal region
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Phosphoadenosine phosphosulphate reductase
Gfo/Idh/MocA-like oxidoreductase N-terminal
Curlin associated repeat-containing protein
TonB-dependent receptor-like beta-barrel
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Cysteine sulfenic acid (-SOH) intermediate
ASP external chaperone domain-containing protein
DNA-directed DNA polymerase family A palm
Type II secretion system protein GspI C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Delta-60 repeat domain-containing protein
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
RNA polymerase sigma factor 70 region 4 type 2
Cytochrome C biogenesis protein transmembrane
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Outer membrane protein beta-barrel domain-containing protein
Iron complex outermembrane recepter protein
Type VI secretion system IcmF C-terminal
MalT-like TPR region domain-containing protein
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Aminoacyl-transfer RNA synthetases class-II family profile
Toxin co-regulated pilus biosynthesis protein Q C-terminal
Large ribosomal subunit protein uL6 alpha-beta
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Chitin-binding type-3 domain-containing protein
Signal transduction histidine kinase internal region
Bacterial type II secretion system protein E
Alpha-D-phosphohexomutase alpha/beta/alpha
Sodium-type polar flagellar protein MotX
Cupin 2 conserved barrel domain-containing protein
Amidohydrolase-related domain-containing protein
Membrane insertase YidC/Oxa/ALB C-terminal
Interacts with tRNA; defines subfamily-specific binding signature
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Helix-hairpin-helix DNA-binding motif class 1
Antitoxin Xre/MbcA/ParS-like toxin-binding
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Survival protein SurE-like phosphatase/nucleotidase
Pili assembly chaperone N-terminal domain-containing protein
RNA 2-O ribose methyltransferase substrate binding
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Proline utilization A proline dehydrogenase N-terminal
Protein prenylyltransferase domain-containing protein
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Sodium/calcium exchanger membrane region
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Outer membrane protein assembly factor BamB
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
ABC-type uncharacterised transport system
5-methyltetrahydrofolate--homocysteine methyltransferase
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Important for beta-aspartyl-AMP intermediate formation
Influences the redox potential of the prosthetic heme and FAD groups
Involved in heme-bound ligand stabilization and O-O bond activation
Outer membrane lipoprotein carrier protein LolA
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Interaction with polymerase core subunit RpoC
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Beta-lactamase-related domain-containing protein
C-type lysozyme inhibitor domain-containing protein
Lysidine-tRNA(Ile) synthetase C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Large ribosomal subunit protein uL15/eL18
Nucleoside-specific outer membrane channel protein Tsx
Flagellar motor switch protein FliN-like C-terminal
D-glutamate N-acetyltransferase-like C-terminal
D-glutamate N-acetyltransferase-like N-terminal
Mandelate racemase/muconate lactonizing enzyme C-terminal
Acyl-ester intermediate; for transpeptidase activity
Penicillin-binding protein transpeptidase
Proton donor; for transglycosylase activity
Amidohydrolase 3 domain-containing protein
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Lytic transglycosylase superhelical linker
Urease accessory protein UreH-like transmembrane
Cytochrome b561 bacterial/Ni-hydrogenase
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Phosphatidic acid phosphatase type 2/haloperoxidase
Outer-membrane lipoprotein carrier protein
Soluble ligand binding domain-containing protein
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Disulphide bond isomerase DsbC/G N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Peptide methionine sulphoxide reductase MsrA
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Translation elongation factor P/YeiP central
Tail specific protease domain-containing protein
Outer membrane lipoprotein-sorting protein
Nitrite/Sulfite reductase ferredoxin-like
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Tetratricopeptide repeat-like domain-containing protein
AMP-activated protein kinase glycogen-binding
Pyruvate dehydrogenase E1 component middle
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Glucose-methanol-choline oxidoreductase N-terminal
Anthranilate synthase component I N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
TonB-dependent receptor plug domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Sodium symporter small subunit predicted
Carbamoyl-phosphate synthase small subunit N-terminal
Prokaryotic-type class I peptide chain release factors
Serine aminopeptidase S33 domain-containing protein
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
PhoD-like phosphatase metallophosphatase
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
TonB C-terminal domain-containing protein
Exonuclease VII large subunit C-terminal
DNA replication/recombination mediator RecO N-terminal
O-(3'-phospho-DNA)-tyrosine intermediate
Peptidase S8/S53 domain-containing protein
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Bacterial transcription activator effector binding
S-adenosylmethionine-dependent methyltransferase
Pseudouridine synthase I TruA alpha/beta
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Chitobiase/beta-hexosaminidases N-terminal
Flagellar hook-length control protein-like C-terminal
Type I phosphodiesterase / nucleotide pyrophosphatase
Polysaccharide biosynthesis protein C-terminal
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Polymerase/histidinol phosphatase N-terminal
Calcineurin-like phosphoesterase domain-containing protein
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
Tryptophan synthase beta chain-like PALP
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Periplasmic binding protein domain-containing protein
Ribose-phosphate pyrophosphokinase N-terminal
Erythronate-4-phosphate dehydrogenase dimerisation
Peptidase MA-like domain-containing protein
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Non-canonical purine NTP phosphatase/PRRC1
Prepilin type IV endopeptidase peptidase
Methyltransferase type 11 domain-containing protein
Bacterial surface antigen (D15) domain-containing protein
PsbP C-terminal domain-containing protein
Flagellar assembly protein T N-terminal domain-containing protein
Phospholipid-binding protein, PBP family
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Bacterial bifunctional deaminase-reductase C-terminal
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
Electron transfer via tryptophanyl radical
Putative Flp pilus-assembly TadG-like N-terminal
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
RNA methyltransferase SpoU/TrmH type C-terminal
Important for interaction with partner proteins
Hypersensitivity response secretion-like HrpJ
Type III secretion system effector delivery regulator TyeA
Glycosyl-hydrolase 97 C-terminal oligomerisation
Glucosamine/galactosamine-6-phosphate isomerase
TRAP-type C4-dicarboxylate transport system, substrate-binding protein
Acyl-CoA dehydrogenase C-terminal bacterial-type
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Carboxypeptidase regulatory-like domain-containing protein
Gly-cisPro motif, important for rejection of L-amino acids
Ysc84 actin-binding domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
TonB-dependent receptor-like beta-barrel domain-containing protein
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Na+/H+ antiporter MnhB subunit-related protein
Nucleophile; cysteine thiosulfonate intermediate
Membrane-bound lytic murein transglycosylase F
Haem-binding uptake Tiki superfamily ChaN
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Thiol:disulfide interchange protein DsbD
Peptidase M14 carboxypeptidase A domain-containing protein
Heat-inducible transcription repressor HrcA C-terminal
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
25S rRNA (uridine-N(3))-methyltransferase BMT5-like
Aspartate/homoserine dehydrogenase NAD-binding
Quercetin 2,3-dioxygenase C-terminal cupin
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Plays an important role in discriminating NADH against NADPH
UDP N-acetylglucosamine O-acyltransferase C-terminal
CobB/CobQ-like glutamine amidotransferase
Metallo-beta-lactamase domain-containing protein
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant domain-containing protein
6-phosphogluconate dehydrogenase C-terminal
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Proton acceptor; specific for (R)-substrate epimerization
Proton acceptor; specific for (S)-substrate epimerization
Tetrahydrodipicolinate-N-succinyltransferase chain A
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Peptidase M1 membrane alanine aminopeptidase
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Glutathionylspermidine synthase pre-ATP-grasp-like
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Glycosyl transferase family 3 N-terminal
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Curli production assembly/transport component CsgE
Aminoacyl-tRNA synthetase class I anticodon-binding
Biopterin-dependent aromatic amino acid hydroxylase family profile
Putative beta-barrel assembly-enhancing protease
Charge relay system; for autoendoproteolytic cleavage activity
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Cellulose synthase operon C C-terminal domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Lysozyme inhibitor LprI N-terminal domain-containing protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Ribosomal RNA adenine methylase transferase N-terminal
tRNA(Met) cytidine acetyltransferase TmcA N-terminal
Peptidase M12B domain-containing protein
Large ribosomal subunit protein uL2 C-terminal
Gamma-glutamylcyclotransferase AIG2-like
Hemoglobin/transferrin/lactoferrin receptor protein
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Important for substrate binding and specificity
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Gp5/Type VI secretion system Vgr protein OB-fold
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
NADH:ubiquinone oxidoreductase intermediate-associated protein 30 domain-containing protein
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Cytochrome c-552/4 domain-containing protein
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Chalcone isomerase domain-containing protein
Yop protein translocation protein D periplasmic
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Required for zinc-mediated homotetramerization and catalytic activity
Transglutaminase-like domain-containing protein
Type II secretion system protein GspC N-terminal
Glycine cleavage T-protein C-terminal barrel
RNA binding; important for wobble base 34 recognition
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Surface lipoprotein of Spirochaetales order
Surface lipoprotein of Spirochaetales order domain-containing protein
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-92)
Endolytic peptidoglycan transglycosylase RlpA
Small ribosomal subunit protein uS4 N-terminal
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Cytochrome c, diheme subunit of cytochrome bc complex peta
Resolvase/invertase-type recombinase catalytic
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Peptide methionine sulfoxide reductase MsrA
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Outer membrane protein assembly factor BamD
Gamma-butyrobetaine hydroxylase-like N-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Putative adhesin domain-containing protein
Chromosomal replication initiator DnaA C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Bacterial virulence factor lipase N-terminal
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
NIF system FeS cluster assembly NifU C-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Polysaccharide biosynthesis protein CapD-like
Sugar fermentation stimulation protein C-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Plays an important role in substrate specificity
Could be important to modulate the pK values of the two catalytic cysteine residues
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
N-end rule aminoacyl transferase C-terminal