Putative beta-barrel assembly-enhancing protease
Aminoacyl-transfer RNA synthetases class-II family profile
Homogentisate 1,2-dioxygenase C-terminal
Homogentisate 1,2-dioxygenase N-terminal
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Carbohydrate-binding domain-containing protein
TonB-dependent receptor-like beta-barrel
Outer membrane protein assembly factor BamA
Iron complex outermembrane recepter protein
Flagellar hook-length control protein-like C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
PhoD-like phosphatase metallophosphatase
Pyrroline-5-carboxylate reductase catalytic N-terminal
Pyrroline-5-carboxylate reductase dimerisation
Peptide methionine sulphoxide reductase MsrA
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Peptidase M1 membrane alanine aminopeptidase
Peptidase M1 membrane alanine aminopeptidase domain-containing protein
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Histidine-specific methyltransferase SAM-dependent
RNA methyltransferase SpoU/TrmH type C-terminal
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
AMP-activated protein kinase glycogen-binding
Solute-binding protein family 3/N-terminal
Cytochrome b561 bacterial/Ni-hydrogenase
NADPH-dependent 7-cyano-7-deazaguanine reductase N-terminal
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Endolytic peptidoglycan transglycosylase RlpA
RlpA-like protein double-psi beta-barrel
Bacterial virulence factor lipase N-terminal
Bacterial virulence factor lipase N-terminal domain-containing protein
Release factor glutamine methyltransferase N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein
Involved in allosteric activation by GTP
Flagellar assembly protein FliH/Type III secretion system HrpE
Could be important to modulate the pK values of the two catalytic cysteine residues
Major facilitator superfamily (MFS) profile
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Tryptophan synthase beta chain-like PALP
Alpha-1,6-glucosidases pullulanase-type C-terminal
Glycoside hydrolase family 13 N-terminal
Pullulanase carbohydrate-binding module 41
TonB-dependent receptor plug domain-containing protein
Translation elongation factor P/YeiP central
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Bacterial type II secretion system protein E
Nitrite/Sulfite reductase ferredoxin-like
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Flagellar Assembly Protein A N-terminal region
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Lysidine-tRNA(Ile) synthetase C-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Alpha-glycerophosphate oxidase C-terminal
Translocation and assembly module subunit TamA
Outer membrane lipoprotein-sorting protein
Metallo-beta-lactamase domain-containing protein
Lipoprotein-attachment site-containing protein
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Outer membrane protein beta-barrel domain-containing protein
Penicillin-binding protein transpeptidase
Glucose-methanol-choline oxidoreductase N-terminal
Putative exodeoxyribonuclease 8 PDDEXK-like
Flagellar basal-body/hook protein C-terminal
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
Chromosomal replication initiator DnaA C-terminal
Soluble ligand binding domain-containing protein
Sugar fermentation stimulation protein C-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Interacts with tRNA; defines subfamily-specific binding signature
RND efflux pump membrane fusion protein barrel-sandwich
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Glycosyltransferase subfamily 4-like N-terminal
Heme-copper oxidase subunit III family profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
Solute-binding protein family 3/N-terminal domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
N6 adenine-specific DNA methyltransferase N-terminal
Polysaccharide chain length determinant N-terminal
Flagellar motor switch protein FliN-like C-terminal
Curli production assembly/transport component CsgG
Outer membrane protein assembly factor BamD
TonB-dependent receptor-like beta-barrel domain-containing protein
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Mandelate racemase/muconate lactonizing enzyme C-terminal
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
DNA polymerase III subunit delta C-terminal
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Serine aminopeptidase S33 domain-containing protein
SMP-30/Gluconolactonase/LRE-like region domain-containing protein
ATP-dependent DNA helicase RecG C-terminal
Acyl-ester intermediate; for transpeptidase activity
Proton donor; for transglycosylase activity
S-adenosylmethionine-dependent methyltransferase
Polysaccharide biosynthesis protein C-terminal
Phosphoethanolamine transferase N-terminal
Plays an important role in discriminating NADH against NADPH
YbaK/aminoacyl-tRNA synthetase-associated
Peptide methionine sulfoxide reductase MsrA
Restriction system protein Mrr-like N-terminal
Glycoside-hydrolase family GH114 TIM-barrel
Glycoside-hydrolase family GH114 TIM-barrel domain-containing protein
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Spore coat protein U domain-containing protein
Important for autoinhibition of adenylyltransferase activity
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Shikimate dehydrogenase substrate binding N-terminal
NIF system FeS cluster assembly NifU N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Cytochrome c-type biogenesis protein CcmF C-terminal
Beta-lactamase-related domain-containing protein
Nucleoside-specific outer membrane channel protein Tsx
Isocitrate dehydrogenase kinase/phosphatase (AceK) kinase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulatory
Glycoside hydrolase family 42 N-terminal
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
Ribose-phosphate pyrophosphokinase N-terminal
Large ribosomal subunit protein uL6 alpha-beta
Alanyl-transfer RNA synthetases family profile
Peptidase M20 dimerisation domain-containing protein
Chalcone isomerase domain-containing protein
Phosphoribosylformylglycinamidine synthase N-terminal
Phosphoribosylformylglycinamidine synthase linker
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase non-repeat region
Amidohydrolase-related domain-containing protein
5-methyltetrahydrofolate--homocysteine methyltransferase
Urease accessory protein UreH-like transmembrane
Penicillin-binding protein activator LpoB
Prepilin type IV endopeptidase peptidase
Exonuclease VII large subunit C-terminal
Endonuclease/exonuclease/phosphatase domain-containing protein
Phosphate ABC transporter substrate-binding protein
Haemolysin activator HlyB C-terminal domain-containing protein
Major facilitator superfamily (MFS) profile domain-containing protein
Type III secretion system flagellar brake protein YcgR PilZN
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Haem-binding uptake Tiki superfamily ChaN
Haem-binding uptake Tiki superfamily ChaN domain-containing protein
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Alpha-D-phosphohexomutase alpha/beta/alpha
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Reversibly protonated during proton transport
Probable transposase IS891/IS1136/IS1341
TonB system biopolymer transport component
3-deoxy-D-manno-octulosonic-acid transferase N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Anthranilate synthase component I N-terminal
Agarase CBM-like domain-containing protein
THAP4-like heme-binding beta-barrel domain-containing protein
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Calcineurin-like phosphoesterase domain-containing protein
AB hydrolase-1 domain-containing protein
Tetratricopeptide repeat-like domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Arginine decarboxylase C-terminal helical
UDP N-acetylglucosamine O-acyltransferase C-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Non-canonical purine NTP phosphatase/PRRC1
Chitin-binding type-3 domain-containing protein
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
GlyGly-CTERM sorting domain-containing protein
Subtilisin-like protease fibronectin type-III
Glucosamine/galactosamine-6-phosphate isomerase
Disulphide bond isomerase DsbC/G N-terminal
Transcription elongation factor GreA/GreB C-terminal
Antitoxin Xre/MbcA/ParS-like toxin-binding
Peptidase M12B domain-containing protein
O-(3'-phospho-DNA)-tyrosine intermediate
Resolvase/invertase-type recombinase catalytic
Glycosyl transferase family 3 N-terminal
Interaction with polymerase core subunit RpoC
Thiol:disulfide interchange protein DsbD
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Pyruvate phosphate dikinase AMP/ATP-binding
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
CD-NTase-associated protein 12/Pycsar effector protein TIR
Transposase IS116/IS110/IS902 C-terminal
Butirosin biosynthesis protein H N-terminal
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
RNA binding; important for wobble base 34 recognition
S-adenosyl-L-homocysteine hydrolase NAD binding
Lysozyme inhibitor LprI N-terminal domain-containing protein
Tetrahydrodipicolinate-N-succinyltransferase chain A
Plays an important role in substrate specificity
Superoxide dismutase copper/zinc binding
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Terminase large subunit gp17-like C-terminal
Cysteine sulfenic acid (-SOH) intermediate
Membrane fusion protein biotin-lipoyl like
Large ribosomal subunit protein uL2 C-terminal
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Prokaryotic-type class I peptide chain release factors
NADH:ubiquinone oxidoreductase intermediate-associated protein 30
NADH:ubiquinone oxidoreductase intermediate-associated protein 30 domain-containing protein
Alginate lyase domain-containing protein
Important for beta-aspartyl-AMP intermediate formation
Flagellar basal body rod protein N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Helix-hairpin-helix DNA-binding motif class 1
Glycine cleavage T-protein C-terminal barrel
Photosynthesis system II assembly factor Ycf48/Hcf136-like
Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein
Regulator of nucleoside diphosphate kinase N-terminal
DNA-directed DNA polymerase family B exonuclease
DNA-directed DNA polymerase family B multifunctional
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Polysaccharide biosynthesis protein CapD-like
Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)
PhoD-like phosphatase metallophosphatase domain-containing protein
Membrane fusion protein biotin-lipoyl like domain-containing protein
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Heat-inducible transcription repressor HrcA C-terminal
DNA-directed DNA polymerase family A palm
Small ribosomal subunit protein uS4 N-terminal
Negative modulator of initiation of replication SeqA N-terminal
Replication modulator SeqA C-terminal DNA-binding
Glucose/Sorbosone dehydrogenase domain-containing protein
Outer-membrane lipoprotein carrier protein
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Glucan biosynthesis periplasmic MdoG C-terminal
TonB C-terminal domain-containing protein
RNA polymerase sigma factor 70 region 4 type 2
Mannose-6-phosphate isomerase type II C-terminal
Proline utilization A proline dehydrogenase N-terminal
Ysc84 actin-binding domain-containing protein
NADH-rubredoxin oxidoreductase C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Cob(I)alamin adenosyltransferase N-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Alginate lyase 2 domain-containing protein
DNA topoisomerase I catalytic core eukaryotic-type
Important for interaction with partner proteins
Cell wall-active antibiotics response LiaF-like C-terminal
Gamma-butyrobetaine hydroxylase-like N-terminal
Transcription elongation factor GreA/GreB N-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Electron transfer via tryptophanyl radical
Fructose-1-6-bisphosphatase class 1 C-terminal
Fructose-1-6-bisphosphatase class I N-terminal
Organic solvent tolerance-like N-terminal
C-type lysozyme inhibitor domain-containing protein
DNA-binding and helicase activity, interacts with RecC
Nuclease activity, interacts with RecD and RecA
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase C-terminal
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase N-terminal
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Dipeptidyl aminopeptidase/acylaminoacyl peptidase
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Required for zinc-mediated homotetramerization and catalytic activity
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
EfeO-type cupredoxin-like domain-containing protein
Signal transduction histidine kinase internal region
Cation-transporting P-type ATPase N-terminal
Glycosyl-hydrolase 97 C-terminal oligomerisation
Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
Carbamoyl-phosphate synthase small subunit N-terminal
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Ion-translocating oxidoreductase complex subunit G
Outer membrane receptor proteins, mostly Fe transport
Gly-cisPro motif, important for rejection of L-amino acids
Aspartate/homoserine dehydrogenase NAD-binding
Aminoacyl-tRNA synthetase class I anticodon-binding
Cellulose synthase operon C C-terminal domain-containing protein
DNA mismatch repair MutH/Type II restriction enzyme Sau3AI
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
RNA 2-O ribose methyltransferase substrate binding
Flagellar assembly protein T N-terminal domain-containing protein
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Protein containing tetratricopeptide repeat
Lytic transglycosylase superhelical linker
Outer-membrane lipoprotein Wza C-terminal
Type II secretion system protein GspI C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Acyl-CoA dehydrogenase C-terminal bacterial-type
Starch-binding associating with outer membrane
Molybdopterin cofactor biosynthesis C (MoaC)
Type II secretion system protein GspC N-terminal
Survival protein SurE-like phosphatase/nucleotidase
Biopterin-dependent aromatic amino acid hydroxylase family profile
Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom
Conserved virulence factor B-like winged helix
Outer membrane protein assembly factor BamB
Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-95)
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase
Uroporphyrinogen-III C-methyltransferase
Pyruvate dehydrogenase E1 component middle
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Peptidase M61 catalytic domain-containing protein
Moves into active site upon enzyme activation, plays a role in electron transfer
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Pili assembly chaperone N-terminal domain-containing protein
Sodium-type polar flagellar protein MotX
ABC-type transport auxiliary lipoprotein component
ABC-type transport auxiliary lipoprotein component domain-containing protein
Positions MEP for the nucleophilic attack
DNA mismatch repair proteins mutS family
Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM
Pseudouridine synthase I TruA alpha/beta
Could play a key role in the communication between the regulatory and the substrate sites
25S rRNA (uridine-N(3))-methyltransferase BMT5-like
Type I restriction modification DNA specificity
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Peptidase S11 D-Ala-D-Ala carboxypeptidase A C-terminal
serine-type D-Ala-D-Ala carboxypeptidase
Large ribosomal subunit protein uL15/eL18
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Toxin co-regulated pilus biosynthesis protein Q C-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
Protein prenylyltransferase domain-containing protein
Type II secretion system protein GspG C-terminal
Pilus formation protein N-terminal domain-containing protein
6-phosphogluconate dehydrogenase C-terminal
Important for substrate binding and specificity
Amidohydrolase 3 domain-containing protein
Transglycosylase SLT domain-containing protein
Phosphatidic acid phosphatase type 2/haloperoxidase
May play a role in metal incorporation in vivo
May play a role in transmitting local conformational changes
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
CobB/CobQ-like glutamine amidotransferase
NIF system FeS cluster assembly NifU C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Pectate lyase superfamily protein domain-containing protein
Thymidylate synthase/dCMP hydroxymethylase