Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Reversibly protonated during proton transport
Cytochrome b561 bacterial/Ni-hydrogenase
Signal transduction histidine kinase HWE region
Glucose-methanol-choline oxidoreductase N-terminal
S-adenosylmethionine-dependent methyltransferase
TonB-dependent receptor-like beta-barrel
tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Major facilitator superfamily (MFS) profile
Aminoacyl-transfer RNA synthetases class-II family profile
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Acyl-CoA dehydrogenase/oxidase C-terminal
Acyl-CoA dehydrogenase/oxidase N-terminal
Glycoside hydrolase family 42 N-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Poly-beta-hydroxybutyrate polymerase N-terminal
Prokaryotic-type class I peptide chain release factors
Polysaccharide chain length determinant N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Shikimate dehydrogenase substrate binding N-terminal
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
Lysozyme inhibitor LprI N-terminal domain-containing protein
Alpha-D-phosphohexomutase alpha/beta/alpha
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycosyltransferase subfamily 4-like N-terminal
Resolvase/invertase-type recombinase catalytic
Peptidase M1 membrane alanine aminopeptidase
Signal transduction histidine kinase dimerisation/phosphoacceptor
PhoD-like phosphatase metallophosphatase
Glucosamine/galactosamine-6-phosphate isomerase
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Helix-hairpin-helix DNA-binding motif class 1
Autotransporter domain-containing protein
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
NAD(P) transhydrogenase alpha subunit C-terminal
Light-independent protochlorophyllide reductase subunit B-like C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
DNA-directed RNA polymerase beta subunit external 1
DNA-directed RNA polymerase subunit 2 hybrid-binding
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Sodium/calcium exchanger membrane region
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
NADH:ubiquinone oxidoreductase chain 4 N-terminal
Membrane insertase YidC/Oxa/ALB C-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Pyridoxamine 5'-phosphate oxidase putative
Pyridoxine 5'-phosphate oxidase dimerisation C-terminal
Right handed beta helix domain-containing protein
Prepilin type IV endopeptidase peptidase
Heme-copper oxidase subunit III family profile
Beta-lactamase hydrolase-like protein phosphatase-like
Magnesium chelatase subunit H N-terminal
Outer membrane protein beta-barrel domain-containing protein
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Positions MEP for the nucleophilic attack
Carbamoyl-phosphate synthase small subunit N-terminal
Penicillin-binding protein transpeptidase
Glutamate-ammonia ligase adenylyltransferase repeated
PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase
Organic solvent tolerance-like N-terminal
Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core
RND efflux pump membrane fusion protein barrel-sandwich
Ribosomal RNA adenine methylase transferase N-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Biopterin-dependent aromatic amino acid hydroxylase family profile
Nitrite/Sulfite reductase ferredoxin-like
Cobaltochelatase subunit CobS N-terminal
Histidine-specific methyltransferase SAM-dependent
Alanyl-transfer RNA synthetases family profile
Large ribosomal subunit protein uL15/eL18
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Molybdopterin cofactor biosynthesis C (MoaC)
O-(3'-phospho-DNA)-tyrosine intermediate
Essential for prephenate dehydratase activity
Photosynthetic reaction centre H subunit N-terminal
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
Metallo-beta-lactamase domain-containing protein
Polymerase/histidinol phosphatase N-terminal
Tryptophan synthase beta chain-like PALP
Interaction with polymerase core subunit RpoC
Tetrahydrodipicolinate-N-succinyltransferase chain A
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Thiolase-like protein type 1 additional C-terminal
DNA-directed DNA polymerase family A palm
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Flagellar assembly protein FliH/Type III secretion system HrpE
Polysaccharide biosynthesis protein C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Fungal lipase-like domain-containing protein
Peptide methionine sulfoxide reductase MsrA
Peptide methionine sulphoxide reductase MsrA
Membrane fusion protein biotin-lipoyl like
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Glycerophosphoryl diester phosphodiesterase membrane
Polypeptide-transport-associated ShlB-type
Methionyl-tRNA synthetase anticodon-binding
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
Exonuclease VII large subunit C-terminal
DNA topoisomerase I catalytic core eukaryotic-type
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Sulfite:cytochrome C oxidoreductase subunit b
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Important for beta-aspartyl-AMP intermediate formation
ABC-type transport auxiliary lipoprotein component
Aconitase A/isopropylmalate dehydratase small subunit swivel
Small ribosomal subunit protein uS4 N-terminal
Type IV methyl-directed restriction enzyme EcoKMcrB subunit DNA-binding
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Lipid/polyisoprenoid-binding YceI-like domain-containing protein
Moybdenum cofactor oxidoreductase dimerisation
PQQ-dependent catabolism-associated beta-propeller protein
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Pseudouridine synthase I TruA alpha/beta
Electron transfer via tryptophanyl radical
RNA 2-O ribose methyltransferase substrate binding
Protein O-mannosyl-transferase C-terminal four TM
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Spore coat protein U domain-containing protein
Chromosomal replication initiator DnaA C-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
RNA 3'-terminal phosphate cyclase insert
Important for interaction with partner proteins
Could be important to modulate the pK values of the two catalytic cysteine residues
Aldehyde oxidase/xanthine dehydrogenase a/b hammerhead
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Required for zinc-mediated homotetramerization and catalytic activity
Quercetin 2,3-dioxygenase C-terminal cupin
Plays an important role in substrate specificity
Acetyl-CoA dehydrogenase-like C-terminal
Bacterial type II secretion system protein E
L,D-transpeptidase catalytic domain-containing protein
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
Survival protein SurE-like phosphatase/nucleotidase
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Acetylserotonin O-methyltransferase dimerisation
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
Type I restriction modification DNA specificity
peptide-methionine (R)-S-oxide reductase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Saccharopine dehydrogenase-like C-terminal
Alpha-L-glutamate ligase-related protein ATP-grasp
Pyruvate phosphate dikinase AMP/ATP-binding
Heat-inducible transcription repressor HrcA C-terminal
PHA accumulation regulator DNA-binding N-terminal
Phosphoribosylformylglycinamidine synthase linker
PEP-CTERM protein-sorting domain-containing protein
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal domain-containing protein
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Histidine phosphotransferase ChpT C-terminal
Cytochrome c-type biogenesis protein CcmF C-terminal
O-(5'-phospho-DNA)-tyrosine intermediate
Large ribosomal subunit protein uL2 C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
7 transmembrane helices usually fused to an inactive transglutaminase
DNA mismatch repair proteins mutS family
Peptidase S9 prolyl oligopeptidase catalytic
Peptidase M1 alanyl aminopeptidase C-terminal
Peptidase M1 alanyl aminopeptidase Ig-like fold
Cleavage (non-hydrolytic); by autocatalysis
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal
Coenzyme F420 hydrogenase/dehydrogenase beta subunit N-terminal
tRNA pseudouridylate synthase B C-terminal
Charge relay system; for autoendoproteolytic cleavage activity
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
General stress protein FMN-binding split barrel
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
SUF system FeS cluster assembly SufBD N-terminal
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
Beta-lactamase-related domain-containing protein
Acyl-CoA dehydrogenase N-terminal bacteria
ATP synthase F1 complex delta/epsilon subunit N-terminal
Polysaccharide biosynthesis protein GumN
Signal recognition particle SRP54 helical bundle
Putative auto-transporter adhesin head GIN
Putative auto-transporter adhesin head GIN domain-containing protein
Glycosyl transferase family 3 N-terminal
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Solute-binding protein family 3/N-terminal
Could play a key role in the communication between the regulatory and the substrate sites
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Cytochrome b/b6 C-terminal region profile
Cytochrome b/b6 N-terminal region profile
NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine
Nucleophile; methyl group acceptor from methylphosphotriester
Putative Flp pilus-assembly TadG-like N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
N-end rule aminoacyl transferase C-terminal
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Ribose-phosphate pyrophosphokinase N-terminal
Outer membrane protein assembly factor BamD
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Alpha-glycerophosphate oxidase C-terminal
RNA binding; important for wobble base 34 recognition
Translation elongation factor P/YeiP central
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
NADH:ubiquinone oxidoreductase 30kDa subunit
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Cysteine sulfenic acid (-SOH) intermediate
CagE TrbE VirB component of type IV transporter system central
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Ribonucleotide reductase large subunit C-terminal
Ribonucleotide reductase large subunit N-terminal
Flagellar motor switch protein FliN-like C-terminal
ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic
Nicotinamide phosphoribosyltransferase N-terminal
Nicotinate/nicotinamide phosphoribosyltransferase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
Large ribosomal subunit protein uL6 alpha-beta
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Pili assembly chaperone N-terminal domain-containing protein
Release factor glutamine methyltransferase N-terminal
Amidohydrolase-related domain-containing protein
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Magnesium-protoporphyrin IX methyltransferase C-terminal