Spore germination GerD central core domain-containing protein
Bacterial transcription activator effector binding
3-hydroxyacyl-CoA dehydrogenase C-terminal
3-hydroxyacyl-CoA dehydrogenase NAD binding
Heat-inducible transcription repressor HrcA C-terminal
Winged helix-turn-helix transcription repressor HrcA DNA-binding
ABC-type glycine betaine transport system substrate-binding
Diacylglycerol glucosyltransferase N-terminal
Glycosyl transferase family 28 C-terminal
ABC transporter substrate-binding protein PnrA-like
Sodium/calcium exchanger membrane region
Major facilitator superfamily (MFS) profile
Anthranilate synthase component I N-terminal
Important for interaction with partner proteins
Important for autoinhibition of adenylyltransferase activity
Meso-diaminopimelate D-dehydrogenase C-terminal
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Copper amine oxidase-like N-terminal domain-containing protein
Gfo/Idh/MocA-like oxidoreductase N-terminal
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
Transposase IS116/IS110/IS902 C-terminal
Heme-copper oxidase subunit III family profile
Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich
Glycosyl hydrolases family 2 sugar binding
Pseudouridine synthase I TruA alpha/beta
Phosphocysteine intermediate; for EIIB activity
SUF system FeS cluster assembly SufBD N-terminal
RNA polymerase sigma factor 70 region 4 type 2
Large ribosomal subunit protein uL6 alpha-beta
Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding
Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Penicillin-binding protein transpeptidase
Pyridine nucleotide-disulphide oxidoreductase dimerisation
Tail specific protease domain-containing protein
Beta-xylosidase C-terminal Concanavalin A-like
Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate
Bacterial type II secretion system protein E
3-beta hydroxysteroid dehydrogenase/isomerase
Essential for prephenate dehydratase activity
Glycoside hydrolase family 42 N-terminal
Prepilin type IV endopeptidase peptidase
Translation initiation factor 3 C-terminal
Translation initiation factor 3 N-terminal
Probable transposase IS891/IS1136/IS1341
Flagellar motor switch protein FliN-like C-terminal
SsuA/THI5-like domain-containing protein
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
Phosphatidylglycerol lysyltransferase C-terminal
Alpha-D-phosphohexomutase alpha/beta/alpha
Cell wall-active antibiotics response LiaF-like C-terminal
Flagellar assembly protein FliH/Type III secretion system HrpE
Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cell envelope-related transcriptional attenuator
Polysaccharide biosynthesis protein C-terminal
Could be important to modulate the pK values of the two catalytic cysteine residues
6-phosphogluconate dehydrogenase C-terminal
Alpha galactosidase C-terminal beta sandwich
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
Microcin J25-processing protein McjB C-terminal
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Solute-binding protein family 3/N-terminal
Inosine/uridine-preferring nucleoside hydrolase
Phosphatidic acid phosphatase type 2/haloperoxidase
Flagellar basal body rod protein N-terminal
Flagellar basal-body/hook protein C-terminal
Aromatic amino acid beta-eliminating lyase/threonine aldolase
Beta-hexosaminidase bacterial type N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Glycosyl hydrolase family 30 beta sandwich
NADH:flavin oxidoreductase/NADH oxidase N-terminal
Pyridoxamine kinase/Phosphomethylpyrimidine kinase
Ferrous iron transport protein B C-terminal
Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups
Gly-cisPro motif, important for rejection of L-amino acids
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
CD-NTase-associated protein 12/Pycsar effector protein TIR
Glycoside hydrolase family 65 C-terminal
Glycoside hydrolase family 65 N-terminal
Glycoside hydrolase family 65 central catalytic
DnaJ homologue subfamily C member 28 conserved
Schiff-base intermediate with D-ribose 5-phosphate
Dinitrogenase iron-molybdenum cofactor biosynthesis
Flagellar hook-associated protein 2 C-terminal
Flagellar hook-associated protein 2 N-terminal
D-glutamate N-acetyltransferase-like C-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Gfo/Idh/MocA-like oxidoreductase C-terminal
Glycosyltransferase subfamily 4-like N-terminal
Sporulation transcription regulator WhiA N-terminal
Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA
Na+-translocating membrane potential-generating system MpsC
Aminoacyl-transfer RNA synthetases class-II family profile
Putative amidase domain-containing protein
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Activator of Hsp90 ATPase homologue 1-like C-terminal
Peptide methionine sulphoxide reductase MsrA
Glycosyl transferase family 3 N-terminal
Extracellular endo-alpha-(1->5)-L-arabinanase C-terminal
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Transcriptional regulator SgrR N-terminal HTH
Septum formation inhibitor MinC C-terminal
Septum formation inhibitor MinC N-terminal
Reversibly protonated during proton transport
Beta-lactamase-related domain-containing protein
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
FAD-dependent oxidoreductase 2 FAD binding
Four-carbon acid sugar kinase N-terminal
Four-carbon acid sugar kinase nucleotide binding
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Pyruvate phosphate dikinase AMP/ATP-binding
2-(S-cysteinyl)pyruvic acid O-phosphothioketal
S-adenosylmethionine-dependent methyltransferase
Major facilitator superfamily associated
Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC
Carbamoyl-phosphate synthetase large subunit-like ATP-binding
Carbamoyl-phosphate synthetase large subunit-like ATP-binding domain-containing protein
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Phosphotransferase system enzyme I N-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal
Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal
Quinolinate phosphoribosyl transferase C-terminal
Quinolinate phosphoribosyl transferase N-terminal
DNA replication/recombination mediator RecO N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Pyrroline-5-carboxylate reductase catalytic N-terminal
UDP-glucose/GDP-mannose dehydrogenase C-terminal
Chromosomal replication initiator DnaA C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
DNA mismatch repair proteins mutS family
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
BAAT/Acyl-CoA thioester hydrolase C-terminal
Transcriptional regulator LacI/GalR-like sensor
Polysaccharide biosynthesis protein CapD-like
Peptidase M1 membrane alanine aminopeptidase
Aconitase A/isopropylmalate dehydratase small subunit swivel
Translation elongation factor P/YeiP central
Thiamin pyrophosphokinase thiamin-binding
DNA-directed DNA polymerase family A palm
Interaction with polymerase core subunit RpoC
O-(5'-phospho-DNA)-tyrosine intermediate
Molybdopterin cofactor biosynthesis C (MoaC)
Schiff-base intermediate with acetaldehyde
Positions MEP for the nucleophilic attack
Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site
Involved in allosteric activation by GTP
Flagellar Assembly Protein A N-terminal region
Tryptophan synthase beta chain-like PALP
Single-stranded-DNA-specific exonuclease RecJ C-terminal
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Ribose-phosphate pyrophosphokinase N-terminal
Glycoside hydrolase family 31 N-terminal
Schiff-base intermediate with substrate; via pyruvic acid
Mannose-6-phosphate isomerase type II C-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Acyl-CoA dehydrogenase/oxidase N-terminal
Schiff-base intermediate with dihydroxyacetone-P
Gram-positive cocci surface proteins LPxTG
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
General stress protein FMN-binding split barrel
Polysaccharide chain length determinant N-terminal
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Phosphomannose isomerase type I catalytic
NIF system FeS cluster assembly NifU N-terminal
Helix-hairpin-helix DNA-binding motif class 1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Ribosome maturation factor RimP C-terminal
Ribosome maturation factor RimP N-terminal
Glycerophosphoryl diester phosphodiesterase
Nitrogenase molybdenum-iron protein beta chain N-terminal
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Glucosamine/galactosamine-6-phosphate isomerase
RNA binding; important for wobble base 34 recognition
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Pyrroline-5-carboxylate reductase dimerisation
HPr(Ser) kinase/phosphorylase N-terminal
Important for the catalytic mechanism of both phosphorylation and dephosphorylation
Important for the catalytic mechanism of dephosphorylation
Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity
Acetylserotonin O-methyltransferase dimerisation
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Carbamoyl-phosphate synthase small subunit N-terminal
Peptidase S9 prolyl oligopeptidase catalytic
Saccharopine dehydrogenase-like C-terminal
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Pyridoxamine 5'-phosphate oxidase putative
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
Tetrapyrrole biosynthesis glutamyl-tRNA reductase dimerisation
N6 adenine-specific DNA methyltransferase N-terminal
Type I restriction modification DNA specificity
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
Glycosyl hydrolase family 98 putative carbohydrate-binding module
Copper amine oxidase domain-containing protein
S-adenosyl-L-homocysteine hydrolase NAD binding
Elongation factor G-binding protein C-terminal treble-clef zinc-finger
Elongation factor G-binding protein N-terminal
Cytochrome C biogenesis protein transmembrane
Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic
Fe-S hydro-lyase tartrate dehydratase beta-type catalytic
Membrane insertase YidC/Oxa/ALB C-terminal
Solute-binding protein family 5 domain-containing protein
3-hydroxyisobutyrate dehydrogenase-like NAD-binding
6-phosphogluconate dehydrogenase NADP-binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Glycosyltransferase family 28 N-terminal
Transcriptional regulator TetR C-terminal Firmicutes type
RDXXRA motif of the pArg binding pocket involved in allosteric regulation
Large ribosomal subunit protein uL2 C-terminal
Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding
Gp5/Type VI secretion system Vgr protein OB-fold
Cation-transporting P-type ATPase N-terminal
Bacterial bifunctional deaminase-reductase C-terminal
Threonine/serine exporter-like N-terminal
Important for beta-aspartyl-AMP intermediate formation
Dipicolinate synthase subunit A N-terminal
Aminoacyl-tRNA synthetase class I anticodon-binding
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Could play a key role in the communication between the regulatory and the substrate sites
tRNA pseudouridine synthase II TruB subfamily 1 C-terminal
tRNA pseudouridylate synthase B C-terminal
Alanyl-transfer RNA synthetases family profile
Pyrimidine nucleoside phosphorylase C-terminal
Exonuclease VII large subunit C-terminal
Family 1 extracellular solute-binding protein
Proton acceptor; for glutaminase activity
Polymerase/histidinol phosphatase N-terminal
YbaK/aminoacyl-tRNA synthetase-associated
Quercetin 2,3-dioxygenase C-terminal cupin
Small ribosomal subunit protein uS4 N-terminal
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Flagellar motor switch protein FliG C-terminal
Flagellar motor switch protein FliG N-terminal
Flagellar motor switch protein FliG middle
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
RNA 2-O ribose methyltransferase substrate binding
Fibronectin type-III domain-containing protein
Cysteine sulfenic acid (-SOH) intermediate
Glycine cleavage T-protein C-terminal barrel
Sporulation stage II protein D amidase enhancer LytB N-terminal
Putative aromatic acid exporter C-terminal
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
Phosphoribosylformylglycinamidine synthase linker
Mandelate racemase/muconate lactonizing enzyme C-terminal
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Signal transduction histidine kinase internal region
Butirosin biosynthesis protein H N-terminal
NIF system FeS cluster assembly NifU C-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
O-(3'-phospho-DNA)-tyrosine intermediate
Ribonucleotide reductase large subunit C-terminal
CobB/CobQ-like glutamine amidotransferase
Cytochrome b/b6 N-terminal region profile
Cytochrome oxidase subunit II copper A binding
Cytochrome oxidase subunit II transmembrane region profile
Methionine ABC transporter substrate-binding protein
ATPase F1/V1/A1 complex alpha/beta subunit N-terminal
ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding
RNA polymerase sigma factor 54 DNA-binding
RNA polymerase sigma factor 54 core-binding
Lysidine-tRNA(Ile) synthetase C-terminal
Tryptophan RNA-binding attenuator protein
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Polynucleotide kinase-phosphatase C-terminal
Polynucleotide kinase-phosphatase ligase
Glutathionylspermidine synthase pre-ATP-grasp-like
DNA-3-methyladenine glycosylase AlkA N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
RND efflux pump membrane fusion protein barrel-sandwich
Signal recognition particle SRP54 helical bundle
Flagellar hook-length control protein-like C-terminal
Sporulation stage IV protein A C-terminal
Ribosomal RNA adenine methylase transferase N-terminal
Transcription regulator AsnC/Lrp ligand binding
Large ribosomal subunit protein bL9 C-terminal
Large ribosomal subunit protein uL15/eL18