Transcription elongation factor GreA/GreB C-terminal
Transcription elongation factor GreA/GreB N-terminal
Cobalamin-independent methionine synthase MetE C-terminal/archaeal
Cobalamin-independent methionine synthase MetE N-terminal
Pyridine nucleotide-disulphide oxidoreductase dimerisation
ATP-dependent DNA helicase RecG C-terminal
RNA polymerase sigma factor 70 region 4 type 2
Alpha-D-phosphohexomutase alpha/beta/alpha
Extradiol ring-cleavage dioxygenase class III enzyme subunit B
Cell envelope-related transcriptional attenuator
Galactofuranosyltransferase GlfT2 N-terminal
Galactofuranosyltransferase-2 C-terminal
Phosphocysteine intermediate; for EIIB activity
Ribosomal RNA adenine methylase transferase N-terminal
Tryptophan synthase beta chain-like PALP
Release factor glutamine methyltransferase N-terminal
Major facilitator superfamily (MFS) profile
Electron transfer flavoprotein alpha/beta-subunit N-terminal
Tetrapyrrole biosynthesis uroporphyrinogen III synthase
Glycine cleavage T-protein C-terminal barrel
Aminoacyl-transfer RNA synthetases class-II family profile
Ribose-phosphate pyrophosphokinase N-terminal
Phosphotransferase system enzyme I N-terminal
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Peptidase M1 membrane alanine aminopeptidase
Formamidopyrimidine-DNA glycosylase catalytic
Proton donor; for beta-elimination activity
Proton donor; for delta-elimination activity
NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
SUF system FeS cluster assembly SufBD N-terminal
Penicillin-binding protein transpeptidase
Involved in Mg(2+) ion dislocation from EF-Tu
Translation elongation factor EFTs/EF1B dimerisation
Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal
Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding
Large ribosomal subunit protein uL6 alpha-beta
Glycosyltransferase subfamily 4-like N-terminal
tRNA-specific 2-thiouridylase MnmA-like C-terminal
tRNA-specific 2-thiouridylase MnmA-like central
Phosphoribosylformylglycinamidine synthase linker
Nucleophile; for GTP cyclohydrolase activity
Proton acceptor; for GTP cyclohydrolase activity
Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding
RNA 2-O ribose methyltransferase substrate binding
Signal transduction histidine kinase subgroup 3 dimerisation and phosphoacceptor
Glycosyl transferase family 3 N-terminal
tRNA pseudouridine synthase II TruB subfamily 2 C-terminal
tRNA pseudouridylate synthase B C-terminal
Thiamine pyrophosphate enzyme N-terminal TPP-binding
Thiamine pyrophosphate enzyme TPP-binding
Large ribosomal subunit protein uL15/eL18
Dihydrodipicolinate reductase C-terminal
Dihydrodipicolinate reductase N-terminal
NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal
Manganese/iron superoxide dismutase C-terminal
Manganese/iron superoxide dismutase N-terminal
Nucleophile; cysteine thiosulfonate intermediate
Phosphoadenosine phosphosulphate reductase
DNA replication/recombination mediator RecO N-terminal
Glycosyl transferase family 28 C-terminal
Glycosyltransferase family 28 N-terminal
Type I restriction modification DNA specificity
5-glutamyl coenzyme A thioester intermediate
Acetyl-CoA hydrolase/transferase C-terminal
Acetyl-CoA hydrolase/transferase N-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal
Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding
Solute-binding protein family 3/N-terminal
Alanyl-transfer RNA synthetases family profile
O-(5'-phospho-DNA)-tyrosine intermediate
O-(3'-phospho-DNA)-tyrosine intermediate
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase middle
Threonine/serine exporter-like N-terminal
N6 adenine-specific DNA methyltransferase N-terminal
Reversibly protonated during proton transport
Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose
Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT C-terminal
Inosine/uridine-preferring nucleoside hydrolase
Aspartate/ornithine carbamoyltransferase Asp/Orn-binding
Aspartate/ornithine carbamoyltransferase carbamoyl-P binding
Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
YbaK/aminoacyl-tRNA synthetase-associated
Pyruvate dehydrogenase E1 component middle
Large ribosomal subunit protein uL11 C-terminal
Large ribosomal subunit protein uL11 N-terminal
Prokaryotic-type class I peptide chain release factors
Phosphatidic acid phosphatase type 2/haloperoxidase
Cysteine sulfenic acid (-SOH) intermediate
Glucose-6-phosphate dehydrogenase C-terminal
Glucose-6-phosphate dehydrogenase NAD-binding
Mycothiol-dependent maleylpyruvate isomerase metal-binding
Glucose-6-phosphate dehydrogenase assembly protein OpcA C-terminal
Glucose-6-phosphate dehydrogenase assembly protein OpcA N-terminal
ATP synthase F1 complex delta/epsilon subunit N-terminal
Cytochrome b/b6 N-terminal region profile
Glucosamine/galactosamine-6-phosphate isomerase
Large ribosomal subunit protein bL25 L25
Large ribosomal subunit protein bL25 beta
Type I restriction enzyme R protein N-terminal
Ribosomal RNA small subunit methyltransferase E PUA-like
Ribosomal RNA small subunit methyltransferase E methyltransferase
Restriction system protein Mrr-like N-terminal
Resuscitation-promoting factor core lysozyme-like
Phosphomannose isomerase type I catalytic
Phosphatidate phosphatase APP1 catalytic
Large ribosomal subunit protein uL5 C-terminal
Large ribosomal subunit protein uL5 N-terminal
Gly-cisPro motif, important for rejection of L-amino acids
Large ribosomal subunit protein bL12 C-terminal
Large ribosomal subunit protein bL12 oligomerization
RNA binding; important for wobble base 34 recognition
Sporulation transcription regulator WhiA N-terminal
DNA helicase Holliday junction RuvA type
Holliday junction DNA helicase RuvA C-terminal
S-adenosylmethionine synthetase C-terminal
S-adenosylmethionine synthetase N-terminal
Polymerase/histidinol phosphatase N-terminal
Chromosomal replication initiator DnaA C-terminal
tRNA(Ile)-lysidine synthase substrate-binding
tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal
TRAP C4-dicarboxylate transport system permease DctM subunit
Molybdopterin cofactor biosynthesis C (MoaC)
Na+/H+ antiporter MnhB subunit-related protein
Bacterial type II secretion system protein E
S-adenosyl-L-homocysteine hydrolase NAD binding
Peptidase S9 prolyl oligopeptidase catalytic
Helix-hairpin-helix DNA-binding motif class 1
Important for beta-aspartyl-AMP intermediate formation
Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding
Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic
NADH-rubredoxin oxidoreductase C-terminal
Nitrite/Sulfite reductase ferredoxin-like
Gfo/Idh/MocA-like oxidoreductase C-terminal
Gfo/Idh/MocA-like oxidoreductase N-terminal
Thymidylate synthase/dCMP hydroxymethylase
Membrane insertase YidC/Oxa/ALB C-terminal
FAD-dependent oxidoreductase 2 FAD binding
Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Schiff-base intermediate with acetaldehyde
N-(5'phosphoribosyl) anthranilate isomerase (PRAI)
Essential for prephenate dehydratase activity
Peptidase S11 D-alanyl-D-alanine carboxypeptidase A N-terminal
Sigma 54 modulation/S30EA ribosomal protein C-terminal
Could play a key role in the communication between the regulatory and the substrate sites
Phosphoenolpyruvate carboxykinase C-terminal P-loop
Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal
Translation elongation factor P/YeiP central
N-sulphoglucosamine sulphohydrolase C-terminal
Ribosome maturation factor RimP N-terminal
Concentrative nucleoside transporter C-terminal
Concentrative nucleoside transporter N-terminal
FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding
NADH:ubiquinone oxidoreductase-like 20kDa subunit
Cytochrome C biogenesis protein transmembrane
DNA polymerase III beta sliding clamp C-terminal
DNA polymerase III beta sliding clamp N-terminal
DNA polymerase III beta sliding clamp central
Large ribosomal subunit protein uL2 C-terminal
Aconitase A/isopropylmalate dehydratase small subunit swivel
DNA/pantothenate metabolism flavoprotein C-terminal
Phosphopantothenoylcysteine decarboxylase
Anthranilate synthase component I N-terminal
Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding
Plays an important role in substrate specificity
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase C-terminal
Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase N-terminal
X-X-X-Leu-X-X-Gly heptad repeat-containing protein
Important for substrate specificity; cannot use PPi as phosphoryl donor
Peptidoglycan recognition protein family
Galactose-1-phosphate uridyl transferase C-terminal
Galactose-1-phosphate uridyl transferase N-terminal
Large ribosomal subunit protein uL30-like ferredoxin-like fold
Involved in ionization of N3 of dUMP, leading to its activation
Arginine biosynthesis bifunctional protein ArgJ alpha chain
Arginine biosynthesis bifunctional protein ArgJ beta chain
Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole
RND efflux pump membrane fusion protein barrel-sandwich
Polysaccharide chain length determinant N-terminal
Pyrimidine nucleoside phosphorylase C-terminal
Endoribonuclease L-PSP/chorismate mutase-like
Positions MEP for the nucleophilic attack
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
DNA-directed RNA polymerase RpoA/D/Rpb3-type
Small ribosomal subunit protein uS4 N-terminal